RetrogeneDB ID: retro_lcha_6

Retrocopy location

• Organism: Coelacanth (Latimeria chalumnae)
• Coordinates: JH126905.1:1102571..1102862(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSLACG00000014792
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: rpl37 (2 of 2)
• Ensembl ID: ENSLACG00000002787
• Aliases: None
• Description: ribosomal protein L37 [Source:ZFIN;Acc:ZDB-GENE-040625-39]

Sequence

>retro_lcha_6
ATGACAAAGGGAACATCATCATTTGGTAAACATCATACTAAGGCACACATTCTTTGCCAGCATTATGGATCTAAGGTATA
CCATCTCCAGAAAGCCACTTGTGGCAAAGGTGGTTACCCTACCAAGCATAAGAGAAAGTACAACTGGAGCGCTAAGGCCA
AGAGACGTAACACCACTGCAACTGGCCATATGAGACACTTGAAAGTTGTACGTCACAGATTTAGGAATGGATTCTGTGAG
GGAACAACACCTAAGCCCAAAAGAGCTGCAGTTGCAGCTTCCAGTTCTTAA

Alignment

ORF - retro_lcha_6 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.29 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKATCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKVV
          MTKGTSSFGK...K.H.LC...GSK.YHLQKATCGK.GYP.K.KRKYNWSAKAKRRNTT.TG.MRHLKVV
Retrocopy MTKGTSSFGKHHTKAHILCQHYGSKVYHLQKATCGKGGYPTKHKRKYNWSAKAKRRNTTATGHMRHLKVV

Parental  YRRFRNGFREGTTPKPKRAAVAASSS
          ..RFRNGF.EGTTPKPKRAAVAASSS
Retrocopy RHRFRNGFCEGTTPKPKRAAVAASSS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
DRP000627_gill	0.00 RPM	296.70 RPM
DRP000627_kidney	0.01 RPM	260.56 RPM
DRP000627_pectoral_fin	0.00 RPM	477.70 RPM
DRP000627_pelvic_fin	0.00 RPM	565.12 RPM
DRP000627_pharynx	0.00 RPM	167.51 RPM
DRP000627_tail_muscle	0.04 RPM	112.01 RPM

ChIP-Seq

Latimeria chalumnae was not studied using ChIP-Seq data.

EST

Latimeria chalumnae was not studied using EST data.

TSS

Latimeria chalumnae was not studied using FANTOM5 data.

Lab

retro_lcha_6 was not experimentally validated.

Homology

Retrocopy orthology:

Latimeria chalumnae does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 26 parental genes, and 286 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000015424	14 retrocopies	retro_amel_1101, retro_amel_1370, retro_amel_1461, retro_amel_1603, retro_amel_167, retro_amel_181, retro_amel_1824, retro_amel_207, retro_amel_237, retro_amel_277, retro_amel_701, retro_amel_888, retro_amel_910, retro_amel_916,
Bos taurus	ENSBTAG00000005142	6 retrocopies	retro_btau_1430, retro_btau_1502, retro_btau_1575, retro_btau_1670, retro_btau_181, retro_btau_243,
Callithrix jacchus	ENSCJAG00000007388	10 retrocopies	retro_cjac_107, retro_cjac_1443, retro_cjac_169, retro_cjac_2091, retro_cjac_2443, retro_cjac_247, retro_cjac_2495, retro_cjac_2654, retro_cjac_2956, retro_cjac_332,
Equus caballus	ENSECAG00000026905	5 retrocopies	retro_ecab_323, retro_ecab_354, retro_ecab_411, retro_ecab_420, retro_ecab_896,
Echinops telfairi	ENSETEG00000003463	23 retrocopies	retro_etel_1003, retro_etel_1030, retro_etel_118, retro_etel_1195, retro_etel_1317, retro_etel_132, retro_etel_1414, retro_etel_1506, retro_etel_1664, retro_etel_1717, retro_etel_1832, retro_etel_1920, retro_etel_201, retro_etel_300, retro_etel_311, retro_etel_360, retro_etel_484, retro_etel_501, retro_etel_572, retro_etel_66, retro_etel_727, retro_etel_732, retro_etel_763,
Homo sapiens	ENSG00000145592	21 retrocopies	retro_hsap_1277, retro_hsap_1424, retro_hsap_156, retro_hsap_1747, retro_hsap_1763, retro_hsap_2009, retro_hsap_2120, retro_hsap_2239, retro_hsap_2265, retro_hsap_2499, retro_hsap_2515, retro_hsap_2923, retro_hsap_343, retro_hsap_3610, retro_hsap_3901, retro_hsap_3958, retro_hsap_4685, retro_hsap_537, retro_hsap_795, retro_hsap_887, retro_hsap_953,
Gorilla gorilla	ENSGGOG00000003241	19 retrocopies	retro_ggor_1002, retro_ggor_1100, retro_ggor_1452, retro_ggor_1488, retro_ggor_1558, retro_ggor_1643, retro_ggor_1670, retro_ggor_2025, retro_ggor_2169, retro_ggor_2246, retro_ggor_2256, retro_ggor_2436, retro_ggor_2629, retro_ggor_2660, retro_ggor_2909, retro_ggor_362, retro_ggor_490, retro_ggor_718, retro_ggor_769,
Latimeria chalumnae	ENSLACG00000002787	1 retrocopy	retro_lcha_6 ,
Loxodonta africana	ENSLAFG00000030052	13 retrocopies	retro_lafr_1101, retro_lafr_1123, retro_lafr_1125, retro_lafr_1136, retro_lafr_215, retro_lafr_374, retro_lafr_448, retro_lafr_507, retro_lafr_532, retro_lafr_619, retro_lafr_775, retro_lafr_985, retro_lafr_986,
Macropus eugenii	ENSMEUG00000011938	3 retrocopies	retro_meug_1060, retro_meug_1633, retro_meug_255,
Myotis lucifugus	ENSMLUG00000001565	10 retrocopies	retro_mluc_1037, retro_mluc_1334, retro_mluc_1441, retro_mluc_1651, retro_mluc_1897, retro_mluc_1917, retro_mluc_2006, retro_mluc_454, retro_mluc_738, retro_mluc_959,
Macaca mulatta	ENSMMUG00000023807	6 retrocopies	retro_mmul_1602, retro_mmul_1672, retro_mmul_206, retro_mmul_329, retro_mmul_976, retro_mmul_997,
Monodelphis domestica	ENSMODG00000020301	3 retrocopies	retro_mdom_130, retro_mdom_1843, retro_mdom_942,
Mus musculus	ENSMUSG00000041841	28 retrocopies	retro_mmus_1333, retro_mmus_1360, retro_mmus_1425, retro_mmus_1560, retro_mmus_1717, retro_mmus_1732, retro_mmus_1804, retro_mmus_1813, retro_mmus_2067, retro_mmus_2379, retro_mmus_2385, retro_mmus_2513, retro_mmus_2559, retro_mmus_2575, retro_mmus_2691, retro_mmus_2811, retro_mmus_2838, retro_mmus_3090, retro_mmus_3222, retro_mmus_3343, retro_mmus_3345, retro_mmus_3364, retro_mmus_3455, retro_mmus_3493, retro_mmus_3503, retro_mmus_3504, retro_mmus_3674, retro_mmus_438,
Nomascus leucogenys	ENSNLEG00000016508	4 retrocopies	retro_nleu_1841, retro_nleu_2065, retro_nleu_2407, retro_nleu_77,
Oryctolagus cuniculus	ENSOCUG00000029674	11 retrocopies	retro_ocun_1063, retro_ocun_1269, retro_ocun_1476, retro_ocun_1491, retro_ocun_1514, retro_ocun_1870, retro_ocun_295, retro_ocun_683, retro_ocun_771, retro_ocun_879, retro_ocun_956,
Otolemur garnettii	ENSOGAG00000034300	7 retrocopies	retro_ogar_127, retro_ogar_1308, retro_ogar_1662, retro_ogar_1667, retro_ogar_2670, retro_ogar_662, retro_ogar_76,
Procavia capensis	ENSPCAG00000007672	5 retrocopies	retro_pcap_252, retro_pcap_270, retro_pcap_349, retro_pcap_436, retro_pcap_53,
Pongo abelii	ENSPPYG00000015422	26 retrocopies	retro_pabe_1058, retro_pabe_1180, retro_pabe_1443, retro_pabe_1532, retro_pabe_1643, retro_pabe_1705, retro_pabe_1756, retro_pabe_1840, retro_pabe_1851, retro_pabe_1865, retro_pabe_1951, retro_pabe_1967, retro_pabe_1985, retro_pabe_212, retro_pabe_2403, retro_pabe_2432, retro_pabe_2962, retro_pabe_3180, retro_pabe_3260, retro_pabe_353, retro_pabe_3549, retro_pabe_3638, retro_pabe_466, retro_pabe_634, retro_pabe_707, retro_pabe_813,
Pan troglodytes	ENSPTRG00000016822	20 retrocopies	retro_ptro_1208, retro_ptro_1219, retro_ptro_1338, retro_ptro_1451, retro_ptro_1460, retro_ptro_152, retro_ptro_1552, retro_ptro_1584, retro_ptro_1605, retro_ptro_1978, retro_ptro_2440, retro_ptro_2654, retro_ptro_2687, retro_ptro_273, retro_ptro_403, retro_ptro_553, retro_ptro_613, retro_ptro_660, retro_ptro_873, retro_ptro_974,
Pteropus vampyrus	ENSPVAG00000000921	8 retrocopies	retro_pvam_1048, retro_pvam_1070, retro_pvam_1478, retro_pvam_315, retro_pvam_49, retro_pvam_738, retro_pvam_803, retro_pvam_844,
Rattus norvegicus	ENSRNOG00000012538	6 retrocopies	retro_rnor_171, retro_rnor_181, retro_rnor_220, retro_rnor_246, retro_rnor_321, retro_rnor_325,
Sarcophilus harrisii	ENSSHAG00000013969	4 retrocopies	retro_shar_295, retro_shar_350, retro_shar_395, retro_shar_715,
Sus scrofa	ENSSSCG00000025883	5 retrocopies	retro_sscr_1004, retro_sscr_1220, retro_sscr_1221, retro_sscr_767, retro_sscr_872,
Tarsius syrichta	ENSTSYG00000006208	21 retrocopies	retro_tsyr_1113, retro_tsyr_1206, retro_tsyr_144, retro_tsyr_1722, retro_tsyr_1893, retro_tsyr_1969, retro_tsyr_201, retro_tsyr_216, retro_tsyr_296, retro_tsyr_307, retro_tsyr_324, retro_tsyr_356, retro_tsyr_426, retro_tsyr_53, retro_tsyr_572, retro_tsyr_682, retro_tsyr_744, retro_tsyr_783, retro_tsyr_829, retro_tsyr_86, retro_tsyr_914,
Tursiops truncatus	ENSTTRG00000010926	7 retrocopies	retro_ttru_1712, retro_ttru_1905, retro_ttru_191, retro_ttru_242, retro_ttru_425, retro_ttru_828, retro_ttru_970,