RetrogeneDB ID: retro_mmus_3222

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 8:79772880..79773171(-)
• Located in intron of: ENSMUSG00000036977

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Rpl37
• Ensembl ID: ENSMUSG00000041841
• Aliases: Rpl37, 3110005M08Rik
• Description: ribosomal protein L37 [Source:MGI Symbol;Acc:MGI:1914531]

Sequence

>retro_mmus_3222
ATGATGAAAGGAAAGGCAGCCTTTGGAAAGCGTCGAAATAGGATGCACATGCCATGCTGCTGCTGTGGCTCTAAGGCCTA
CCACCTTCAGAAGTGAGCCCGCCACAAATGTGGCTACTCTGTCAAATGCAAGACAAATTATAACTGAAGTGCCAACACTA
AGAGATGAAACACTATGGGGACTGGGCAGATGAGGCTCCTAAAAATTGTCTATCACAGATTTAGACATGGATTCCAAGAA
GGAACAACACCTAAACCCAAGAGGGCAGCTGTTGCAGCATCTAGTTCATCT

Alignment

ORF - retro_mmus_3222 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.13 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIV
          M.KG...FGKRRN..H..C..CGSKAYHLQK....KCGY..K.K..YN.SA..KR.NT.GTG.MR.LKIV
Retrocopy MMKGKAAFGKRRNRMHMPCCCCGSKAYHLQK*ARHKCGYSVKCKTNYN*SANTKR*NTMGTGQMRLLKIV

Parental  YRRFRHGFREGTTPKPKRAAVAASSSS
          Y.RFRHGF.EGTTPKPKRAAVAASSSS
Retrocopy YHRFRHGFQEGTTPKPKRAAVAASSSS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.09 RPM	65.70 RPM
SRP007412_cerebellum	0.09 RPM	37.21 RPM
SRP007412_heart	0.00 RPM	58.93 RPM
SRP007412_kidney	0.04 RPM	45.29 RPM
SRP007412_liver	0.00 RPM	67.59 RPM
SRP007412_testis	0.37 RPM	51.18 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_3222 was not detected

EST

No EST(s) were mapped for retro_mmus_3222 retrocopy.

TSS

No TSS is located nearby retro_mmus_3222 retrocopy 5' end.

Lab

retro_mmus_3222 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_3222 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 96 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005142	6 retrocopies	retro_btau_1430, retro_btau_1502, retro_btau_1575, retro_btau_1670, retro_btau_181, retro_btau_243,
Callithrix jacchus	ENSCJAG00000007388	10 retrocopies	retro_cjac_107, retro_cjac_1443, retro_cjac_169, retro_cjac_2091, retro_cjac_2443, retro_cjac_247, retro_cjac_2495, retro_cjac_2654, retro_cjac_2956, retro_cjac_332,
Latimeria chalumnae	ENSLACG00000002787	1 retrocopy	retro_lcha_6,
Loxodonta africana	ENSLAFG00000030052	13 retrocopies	retro_lafr_1101, retro_lafr_1123, retro_lafr_1125, retro_lafr_1136, retro_lafr_215, retro_lafr_374, retro_lafr_448, retro_lafr_507, retro_lafr_532, retro_lafr_619, retro_lafr_775, retro_lafr_985, retro_lafr_986,
Macaca mulatta	ENSMMUG00000023807	6 retrocopies	retro_mmul_1602, retro_mmul_1672, retro_mmul_206, retro_mmul_329, retro_mmul_976, retro_mmul_997,
Monodelphis domestica	ENSMODG00000020301	3 retrocopies	retro_mdom_130, retro_mdom_1843, retro_mdom_942,
Mus musculus	ENSMUSG00000041841	28 retrocopies	retro_mmus_1333, retro_mmus_1360, retro_mmus_1425, retro_mmus_1560, retro_mmus_1717, retro_mmus_1732, retro_mmus_1804, retro_mmus_1813, retro_mmus_2067, retro_mmus_2379, retro_mmus_2385, retro_mmus_2513, retro_mmus_2559, retro_mmus_2575, retro_mmus_2691, retro_mmus_2811, retro_mmus_2838, retro_mmus_3090, retro_mmus_3222 , retro_mmus_3343, retro_mmus_3345, retro_mmus_3364, retro_mmus_3455, retro_mmus_3493, retro_mmus_3503, retro_mmus_3504, retro_mmus_3674, retro_mmus_438,
Oryctolagus cuniculus	ENSOCUG00000029674	11 retrocopies	retro_ocun_1063, retro_ocun_1269, retro_ocun_1476, retro_ocun_1491, retro_ocun_1514, retro_ocun_1870, retro_ocun_295, retro_ocun_683, retro_ocun_771, retro_ocun_879, retro_ocun_956,
Otolemur garnettii	ENSOGAG00000034300	7 retrocopies	retro_ogar_127, retro_ogar_1308, retro_ogar_1662, retro_ogar_1667, retro_ogar_2670, retro_ogar_662, retro_ogar_76,
Rattus norvegicus	ENSRNOG00000012538	6 retrocopies	retro_rnor_171, retro_rnor_181, retro_rnor_220, retro_rnor_246, retro_rnor_321, retro_rnor_325,
Sus scrofa	ENSSSCG00000025883	5 retrocopies	retro_sscr_1004, retro_sscr_1220, retro_sscr_1221, retro_sscr_767, retro_sscr_872,