RetrogeneDB ID: retro_ggor_385

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:46668631..46669079(-)
• Located in intron of: ENSGGOG00000001535

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: OSTC
• Ensembl ID: ENSGGOG00000026873
• Aliases: None
• Description: None

Sequence

>retro_ggor_385
ATGGAGACTTTGTACCGTGTCCCATTCTTTGTGCTCGAATGTCCTAACCTGAAGCTGAAGAAGCCACCCTGGCTGCCCAT
GCCGTTGGCCATGACTGTGTATGCTCTGGTGGTGGCGTCTTACTTCCTCATCACCAGAGGAATAATTTATGATGTTATTG
TTGAACCTCCAAGTGTTGGTTCTATGACTGATGAACATGGGCATCAGAGGCCAGTAGCTTTCTTGGCCTACAGTAAATGG
ACAGTATGTTATGGAAGGACTTGCATCCAGCTTCCTGTTTACAGTGGGAGGTTTAGGTTTCATAATCCTGGACTGATTGA
ATGCACCAAATATCCCAAAACTCAGTAGATTTCTTCTTCTATTCATTGGATTCGTGTGTGTCTTACTGAGGTTTTTCATG
GCTACTCAAGTATTCATGAGAATGAAACTGCCAGGCTATCTGATGGGT

Alignment

ORF - retro_ggor_385 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.16 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQR
          METLYRVPF.VLECPNLKLKKPPWL.MP.AMTVYALVV.SYFLIT.GIIYDVIVEPPSVGSMTDEHGHQR
Retrocopy METLYRVPFFVLECPNLKLKKPPWLPMPLAMTVYALVVASYFLITRGIIYDVIVEPPSVGSMTDEHGHQR

Parental  PVA-FLAYR-VNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMA-RV
          PVA.FL....VNGQY.MEGLASSFLFT.GGLGFIILD..NAPNIPKL.RFLLLFIGFVCVLL.FFMA..V
Retrocopy PVA<FLGLQ<VNGQYVMEGLASSFLFTVGGLGFIILD*LNAPNIPKLSRFLLLFIGFVCVLLRFFMATQV

Parental  FMRMKLPGYLMG
          FMRMKLPGYLMG
Retrocopy FMRMKLPGYLMG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	4.22 RPM
SRP007412_cerebellum	0.08 RPM	5.99 RPM
SRP007412_heart	0.00 RPM	2.47 RPM
SRP007412_kidney	0.00 RPM	18.36 RPM
SRP007412_liver	0.00 RPM	38.38 RPM
SRP007412_testis	0.00 RPM	14.81 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_385 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_385 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_376

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 77 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001753	2 retrocopies	retro_amel_1110, retro_amel_165,
Bos taurus	ENSBTAG00000011611	1 retrocopy	retro_btau_753,
Canis familiaris	ENSCAFG00000011286	12 retrocopies	retro_cfam_1129, retro_cfam_1206, retro_cfam_1459, retro_cfam_1462, retro_cfam_1575, retro_cfam_1851, retro_cfam_1910, retro_cfam_1948, retro_cfam_2003, retro_cfam_263, retro_cfam_296, retro_cfam_814,
Callithrix jacchus	ENSCJAG00000016002	3 retrocopies	retro_cjac_121, retro_cjac_2981, retro_cjac_324,
Cavia porcellus	ENSCPOG00000024467	1 retrocopy	retro_cpor_659,
Dasypus novemcinctus	ENSDNOG00000011172	2 retrocopies	retro_dnov_12, retro_dnov_1973,
Echinops telfairi	ENSETEG00000003717	4 retrocopies	retro_etel_1564, retro_etel_492, retro_etel_878, retro_etel_970,
Homo sapiens	ENSG00000198856	7 retrocopies	retro_hsap_1746, retro_hsap_2013, retro_hsap_2972, retro_hsap_3598, retro_hsap_3686, retro_hsap_376, retro_hsap_4246,
Gorilla gorilla	ENSGGOG00000026873	6 retrocopies	retro_ggor_1457, retro_ggor_2060, retro_ggor_215, retro_ggor_2427, retro_ggor_370, retro_ggor_385 ,
Loxodonta africana	ENSLAFG00000026381	7 retrocopies	retro_lafr_1046, retro_lafr_17, retro_lafr_222, retro_lafr_231, retro_lafr_444, retro_lafr_549, retro_lafr_618,
Myotis lucifugus	ENSMLUG00000000478	2 retrocopies	retro_mluc_1366, retro_mluc_1511,
Monodelphis domestica	ENSMODG00000020599	1 retrocopy	retro_mdom_428,
Mustela putorius furo	ENSMPUG00000008869	1 retrocopy	retro_mputfur_1451,
Mus musculus	ENSMUSG00000041084	1 retrocopy	retro_mmus_648,
Nomascus leucogenys	ENSNLEG00000012929	11 retrocopies	retro_nleu_1372, retro_nleu_1436, retro_nleu_2026, retro_nleu_2265, retro_nleu_2274, retro_nleu_2665, retro_nleu_2796, retro_nleu_2826, retro_nleu_297, retro_nleu_474, retro_nleu_923,
Oryctolagus cuniculus	ENSOCUG00000011056	2 retrocopies	retro_ocun_1318, retro_ocun_7,
Otolemur garnettii	ENSOGAG00000033684	1 retrocopy	retro_ogar_578,
Pan troglodytes	ENSPTRG00000024222	1 retrocopy	retro_ptro_34,
Pteropus vampyrus	ENSPVAG00000005915	1 retrocopy	retro_pvam_924,
Rattus norvegicus	ENSRNOG00000023322	1 retrocopy	retro_rnor_2297,
Sus scrofa	ENSSSCG00000009145	1 retrocopy	retro_sscr_503,
Ictidomys tridecemlineatus	ENSSTOG00000021644	6 retrocopies	retro_itri_1211, retro_itri_1386, retro_itri_15, retro_itri_1571, retro_itri_789, retro_itri_863,
Tarsius syrichta	ENSTSYG00000000724	2 retrocopies	retro_tsyr_1193, retro_tsyr_921,
Tursiops truncatus	ENSTTRG00000003446	1 retrocopy	retro_ttru_582,