RetrogeneDB ID: retro_ggor_1852

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:60003966..60004332(+)
• Located in intron of: ENSGGOG00000015441

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENSG00000131469
• Ensembl ID: ENSGGOG00000026039
• Aliases: None
• Description: 60S ribosomal protein L27 [Source:UniProtKB/TrEMBL;Acc:G3S8W1]

Sequence

>retro_ggor_1852
ATGGGCAAGTTCATGAAAAAGTGGGAAAGTGGTGCTGGTCCTGGCTGGATGCTACTCTGGACGCAAAGCCATTATCATGA
AGGACATTGATGATGGCACCTCAGTCCATTCTTACAGTCATGCTTTGGTAGCTGGAATTGACTGCTATCCTCACAAAGTG
ACAGCTGCCATAGGCAAGAAGATCTCCAAGAGGTCAAGGATCAAGTCTTTTGCAAAAGCTTATAACTACAATCACCTCAT
GCCCACAAGGTACTCTGTGGATAGCCTCTTGGACAAACTGTCATCAACAAGGATCTCCTCAAAGACCTTGCTCTTAAACA
CAAAGCGTGATGGGAGGCCAAGATCAAGTTCAAAGAAAGGTACAAG

Alignment

ORF - retro_ggor_1852 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.0 %
• Parental protein coverage: 90.44 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MGKFMKP-GKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIK
          MGKFMK..GKVVLVLAG.YSGRKA.I.K.IDDGTS...YSHALVAGID.YP.KVTAA.G.KKI.KRS.IK
Retrocopy MGKFMKK>GKVVLVLAGCYSGRKAIIMKDIDDGTSVHSYSHALVAGIDCYPHKVTAAIG-KKISKRSRIK

Parental  SFVKVYNYNHLMPTRYSVDIPLDK-TVVNKDVFRDPALKRKARREAKVKFEERYK
          SF.K.YNYNHLMPTRYSVD..LDK.TV.NKD...D.ALK.KA..EAK.KF.ERYK
Retrocopy SFAKAYNYNHLMPTRYSVDSLLDK<TVINKDLLKDLALKHKA*WEAKIKFKERYK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	138.16 RPM
SRP007412_cerebellum	0.04 RPM	131.47 RPM
SRP007412_heart	0.00 RPM	125.77 RPM
SRP007412_kidney	0.29 RPM	178.23 RPM
SRP007412_liver	0.32 RPM	209.68 RPM
SRP007412_testis	0.00 RPM	146.90 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1852 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1852 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 32 parental genes, and 183 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000000200	3 retrocopies	retro_amel_122, retro_amel_37, retro_amel_674,
Bos taurus	ENSBTAG00000017441	6 retrocopies	retro_btau_1113, retro_btau_129, retro_btau_1565, retro_btau_1855, retro_btau_338, retro_btau_394,
Canis familiaris	ENSCAFG00000014630	6 retrocopies	retro_cfam_1193, retro_cfam_2109, retro_cfam_339, retro_cfam_364, retro_cfam_947, retro_cfam_959,
Callithrix jacchus	ENSCJAG00000013067	9 retrocopies	retro_cjac_1345, retro_cjac_1350, retro_cjac_1543, retro_cjac_1630, retro_cjac_2210, retro_cjac_275, retro_cjac_2828, retro_cjac_369, retro_cjac_776,
Cavia porcellus	ENSCPOG00000027359	3 retrocopies	retro_cpor_1178, retro_cpor_677, retro_cpor_715,
Dipodomys ordii	ENSDORG00000010907	6 retrocopies	retro_dord_154, retro_dord_335, retro_dord_477, retro_dord_527, retro_dord_601, retro_dord_784,
Equus caballus	ENSECAG00000007500	1 retrocopy	retro_ecab_132,
Echinops telfairi	ENSETEG00000002811	23 retrocopies	retro_etel_1230, retro_etel_1250, retro_etel_1302, retro_etel_1312, retro_etel_1453, retro_etel_1496, retro_etel_160, retro_etel_177, retro_etel_2055, retro_etel_2170, retro_etel_278, retro_etel_306, retro_etel_349, retro_etel_415, retro_etel_461, retro_etel_467, retro_etel_548, retro_etel_555, retro_etel_751, retro_etel_753, retro_etel_775, retro_etel_805, retro_etel_971,
Felis catus	ENSFCAG00000013142	6 retrocopies	retro_fcat_1026, retro_fcat_1184, retro_fcat_1824, retro_fcat_228, retro_fcat_698, retro_fcat_78,
Homo sapiens	ENSG00000131469	6 retrocopies	retro_hsap_1161, retro_hsap_1312, retro_hsap_2112, retro_hsap_2204, retro_hsap_238, retro_hsap_3787,
Gorilla gorilla	ENSGGOG00000026039	6 retrocopies	retro_ggor_1741, retro_ggor_1852 , retro_ggor_2546, retro_ggor_2630, retro_ggor_298, retro_ggor_907,
Loxodonta africana	ENSLAFG00000014220	3 retrocopies	retro_lafr_443, retro_lafr_739, retro_lafr_965,
Microcebus murinus	ENSMICG00000014214	5 retrocopies	retro_mmur_1340, retro_mmur_1498, retro_mmur_1542, retro_mmur_673, retro_mmur_695,
Myotis lucifugus	ENSMLUG00000004119	1 retrocopy	retro_mluc_359,
Macaca mulatta	ENSMMUG00000008090	7 retrocopies	retro_mmul_1646, retro_mmul_1997, retro_mmul_418, retro_mmul_478, retro_mmul_52, retro_mmul_680, retro_mmul_925,
Monodelphis domestica	ENSMODG00000015128	1 retrocopy	retro_mdom_1141,
Mustela putorius furo	ENSMPUG00000009913	11 retrocopies	retro_mputfur_1041, retro_mputfur_1108, retro_mputfur_1182, retro_mputfur_1307, retro_mputfur_1530, retro_mputfur_303, retro_mputfur_413, retro_mputfur_595, retro_mputfur_675, retro_mputfur_735, retro_mputfur_980,
Mus musculus	ENSMUSG00000063316	2 retrocopies	retro_mmus_223, retro_mmus_277,
Nomascus leucogenys	ENSNLEG00000011901	2 retrocopies	retro_nleu_334, retro_nleu_45,
Oryctolagus cuniculus	ENSOCUG00000003872	1 retrocopy	retro_ocun_263,
Otolemur garnettii	ENSOGAG00000003940	14 retrocopies	retro_ogar_1091, retro_ogar_1297, retro_ogar_1478, retro_ogar_1692, retro_ogar_1887, retro_ogar_2189, retro_ogar_2354, retro_ogar_2625, retro_ogar_2687, retro_ogar_2915, retro_ogar_3207, retro_ogar_3294, retro_ogar_3381, retro_ogar_618,
Procavia capensis	ENSPCAG00000013249	4 retrocopies	retro_pcap_123, retro_pcap_146, retro_pcap_203, retro_pcap_227,
Pan troglodytes	ENSPTRG00000009232	6 retrocopies	retro_ptro_127, retro_ptro_1673, retro_ptro_208, retro_ptro_2569, retro_ptro_794, retro_ptro_900,
Pteropus vampyrus	ENSPVAG00000008817	4 retrocopies	retro_pvam_1084, retro_pvam_1231, retro_pvam_25, retro_pvam_509,
Rattus norvegicus	ENSRNOG00000020674	8 retrocopies	retro_rnor_1150, retro_rnor_125, retro_rnor_1257, retro_rnor_1968, retro_rnor_2594, retro_rnor_2989, retro_rnor_386, retro_rnor_414,
Sorex araneus	ENSSARG00000011131	10 retrocopies	retro_sara_254, retro_sara_292, retro_sara_493, retro_sara_498, retro_sara_547, retro_sara_611, retro_sara_62, retro_sara_672, retro_sara_685, retro_sara_696,
Sarcophilus harrisii	ENSSHAG00000012042	4 retrocopies	retro_shar_10, retro_shar_253, retro_shar_730, retro_shar_741,
Sus scrofa	ENSSSCG00000025507	5 retrocopies	retro_sscr_109, retro_sscr_1154, retro_sscr_576, retro_sscr_683, retro_sscr_943,
Ictidomys tridecemlineatus	ENSSTOG00000020555	5 retrocopies	retro_itri_1295, retro_itri_1812, retro_itri_283, retro_itri_836, retro_itri_926,
Tarsius syrichta	ENSTSYG00000003167	12 retrocopies	retro_tsyr_1032, retro_tsyr_1154, retro_tsyr_1711, retro_tsyr_2036, retro_tsyr_381, retro_tsyr_476, retro_tsyr_602, retro_tsyr_787, retro_tsyr_816, retro_tsyr_822, retro_tsyr_95, retro_tsyr_989,
Tursiops truncatus	ENSTTRG00000011739	2 retrocopies	retro_ttru_1049, retro_ttru_1535,
Vicugna pacos	ENSVPAG00000002574	1 retrocopy	retro_vpac_324,