RetrogeneDB ID: retro_rnor_2067

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 4:147450356..147450691(-)
• Located in intron of: ENSRNOG00000008393

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Eif1
• Ensembl ID: ENSRNOG00000033765
• Aliases: Eif1, Sui1-rs1
• Description: eukaryotic translation initiation factor 1 [Source:RefSeq peptide;Acc:NP_001099307]

Sequence

>retro_rnor_2067
TTGGCCATTGTCCAGAACCTCCACTCTTTCAACCCCTTTGCTGATTCAAGTAAGAGTAATTGCCTGCTTTCTATGGGCAC
TGAGGATTATACTGATAAACAAGTTCAACAGAGAAATGACAGGAAGACCCTGACCCAAGGGCTCACTGATGATTAATTTA
AGAACAAACCAGTGAGGGCATTTAAGAAGAAATTCTGCCTACAATGGTACTTTAATTGAGCATCCCCAATATGAAGAAGT
AATTAAGCTAAAGGGTGACCTTCTCAAGAACACATGCCAGTTCCTGACAAGAGAGTGGACTGGCTACGGACAATCAGCTG
AAGGTTCCCAAGTTT

Alignment

ORF - retro_rnor_2067 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 62.61 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKF-AC
          ....QNLHSF.PFAD.SK...LL..GTEDY.....QQRN.RKTLT..QG..DD..K.K.V.AFKKKF.A.
Retrocopy LAIVQNLHSFNPFADSSKSNCLLSMGTEDYTDKQVQQRNDRKTLT--QGLTDD*FKNKPVRAFKKKF>AY

Parental  NGTVIEHPEYGEVIQLQGDQRKNICQFLI-EIGLAKDDQLKVHGF
          NGT.IEHP.Y.EVI.L.GD..KN.CQFL..E.GLA.D.QLKV..F
Retrocopy NGTLIEHPQYEEVIKLKGDLLKNTCQFLT>ESGLATDNQLKVPKF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.07 RPM	184.41 RPM
SRP017611_kidney	0.00 RPM	169.01 RPM
SRP017611_liver	0.00 RPM	68.25 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_2067 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_2067 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_2067 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 26 parental genes, and 148 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005620	9 retrocopies	retro_amel_1335, retro_amel_335, retro_amel_567, retro_amel_575, retro_amel_587, retro_amel_666, retro_amel_782, retro_amel_798, retro_amel_823,
Bos taurus	ENSBTAG00000002282	1 retrocopy	retro_btau_63,
Canis familiaris	ENSCAFG00000029584	4 retrocopies	retro_cfam_1465, retro_cfam_1479, retro_cfam_359, retro_cfam_655,
Choloepus hoffmanni	ENSCHOG00000008378	7 retrocopies	retro_chof_1435, retro_chof_170, retro_chof_2236, retro_chof_2293, retro_chof_2625, retro_chof_320, retro_chof_708,
Callithrix jacchus	ENSCJAG00000012120	6 retrocopies	retro_cjac_1237, retro_cjac_2089, retro_cjac_346, retro_cjac_3815, retro_cjac_600, retro_cjac_84,
Cavia porcellus	ENSCPOG00000014350	3 retrocopies	retro_cpor_42, retro_cpor_613, retro_cpor_643,
Dasypus novemcinctus	ENSDNOG00000007856	11 retrocopies	retro_dnov_1098, retro_dnov_1110, retro_dnov_1368, retro_dnov_148, retro_dnov_1516, retro_dnov_1668, retro_dnov_1807, retro_dnov_2062, retro_dnov_2209, retro_dnov_402, retro_dnov_421,
Equus caballus	ENSECAG00000012516	1 retrocopy	retro_ecab_436,
Felis catus	ENSFCAG00000024455	2 retrocopies	retro_fcat_1555, retro_fcat_74,
Homo sapiens	ENSG00000173812	2 retrocopies	retro_hsap_1659, retro_hsap_271,
Gorilla gorilla	ENSGGOG00000027201	2 retrocopies	retro_ggor_1251, retro_ggor_318,
Macropus eugenii	ENSMEUG00000015360	6 retrocopies	retro_meug_1513, retro_meug_1635, retro_meug_2189, retro_meug_315, retro_meug_749, retro_meug_821,
Myotis lucifugus	ENSMLUG00000005077	3 retrocopies	retro_mluc_233, retro_mluc_305, retro_mluc_330,
Mustela putorius furo	ENSMPUG00000010883	6 retrocopies	retro_mputfur_1019, retro_mputfur_1072, retro_mputfur_1239, retro_mputfur_1299, retro_mputfur_41, retro_mputfur_752,
Mus musculus	ENSMUSG00000035530	27 retrocopies	retro_mmus_1033, retro_mmus_1063, retro_mmus_1191, retro_mmus_1213, retro_mmus_1286, retro_mmus_1392, retro_mmus_1448, retro_mmus_1652, retro_mmus_2045, retro_mmus_2270, retro_mmus_2604, retro_mmus_2737, retro_mmus_2990, retro_mmus_3043, retro_mmus_3047, retro_mmus_308, retro_mmus_3141, retro_mmus_3164, retro_mmus_3386, retro_mmus_3468, retro_mmus_3471, retro_mmus_3638, retro_mmus_3639, retro_mmus_3963, retro_mmus_512, retro_mmus_585, retro_mmus_840,
Nomascus leucogenys	ENSNLEG00000011013	3 retrocopies	retro_nleu_1482, retro_nleu_2005, retro_nleu_92,
Otolemur garnettii	ENSOGAG00000031577	6 retrocopies	retro_ogar_1349, retro_ogar_1701, retro_ogar_1940, retro_ogar_2645, retro_ogar_2899, retro_ogar_856,
Pongo abelii	ENSPPYG00000029667	1 retrocopy	retro_pabe_127,
Pan troglodytes	ENSPTRG00000009175	3 retrocopies	retro_ptro_1261, retro_ptro_227, retro_ptro_2923,
Pteropus vampyrus	ENSPVAG00000010629	4 retrocopies	retro_pvam_1152, retro_pvam_471, retro_pvam_665, retro_pvam_923,
Rattus norvegicus	ENSRNOG00000032769	1 retrocopy	retro_rnor_520,
Rattus norvegicus	ENSRNOG00000033765	15 retrocopies	retro_rnor_1088, retro_rnor_1347, retro_rnor_1518, retro_rnor_1744, retro_rnor_1971, retro_rnor_2067 , retro_rnor_2171, retro_rnor_2203, retro_rnor_2532, retro_rnor_2548, retro_rnor_2579, retro_rnor_45, retro_rnor_532, retro_rnor_571, retro_rnor_65,
Sarcophilus harrisii	ENSSHAG00000005729	1 retrocopy	retro_shar_42,
Sus scrofa	ENSSSCG00000017430	6 retrocopies	retro_sscr_1114, retro_sscr_1126, retro_sscr_1192, retro_sscr_394, retro_sscr_402, retro_sscr_922,
Ictidomys tridecemlineatus	ENSSTOG00000002719	15 retrocopies	retro_itri_1082, retro_itri_1184, retro_itri_1369, retro_itri_1398, retro_itri_1401, retro_itri_1716, retro_itri_1784, retro_itri_1846, retro_itri_220, retro_itri_285, retro_itri_526, retro_itri_606, retro_itri_688, retro_itri_702, retro_itri_977,
Tursiops truncatus	ENSTTRG00000017135	3 retrocopies	retro_ttru_1664, retro_ttru_224, retro_ttru_315,