RetrogeneDB ID: retro_chof_1136

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_209265:76..518(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: FAM60A
• Ensembl ID: ENSCHOG00000007193
• Aliases: None
• Description: family with sequence similarity 60, member A [Source:HGNC Symbol;Acc:30702]

Sequence

>retro_chof_1136
TGGAATCGTGTGTTAGACACAAGGGCAGGACTCAATCTGAAGACTACATCGAAACCAAAGAAAGTGAAAACTCTGTCTGG
AAACAGGATAAAAAGCAACCAGATCAGTAAAGTGCAGAAAGAATTTAAACATCATAATTCTGATGTTCACAATACCAGTT
CAAGTGCCTTCCTAGTCCAGTCTCATTATACTTACCAGTTCAAATGATGGCTCAGATACTGAGATCACTTCTGGCTCTAA
TAGAGCACCAGTCTTCTCCTTTTTAGATCTCACATACTAGAACAGACAGAAAATAGGTTGTGGGATTACCTGTAAACGCC
GTTTTGGGGAAGTCCTCATTGACACACATCTACTCAAGCCTTGCTGCACAATAAAGAAAACAGCTGCTGAGAAGCCAGTG
GAGCAGGGGTCAGAGACTTTACTCATCTATACTCAGGAGTGG

Alignment

ORF - retro_chof_1136 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.14 %
• Parental protein coverage: 66.97 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  WNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFKRHXXXXXXXTSSASPAQSPCYSNQ-SD
          WN.V.D.RAG..LKTT.KPKKVKTLSGNRIKSNQISK.QKEFK.H........SSA...QS..Y..Q.S.
Retrocopy WNRVLDTRAGLNLKTTSKPKKVKTLSGNRIKSNQISKVQKEFKHHNSDVHNTSSSAFLVQSH-YTYQ>SN

Parental  DGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSNKKTTAEKPEEQGPE
          DGSDTE..SGSNR.PVFSFLDLTY..RQKI.CGI..K.RFGEVLIDTHL.KPCC..KKT.AEKP.EQG.E
Retrocopy DGSDTEITSGSNRAPVFSFLDLTY*NRQKIGCGITCKRRFGEVLIDTHLLKPCCTIKKTAAEKPVEQGSE

Parental  PLPISTQEW
          .L.I.TQEW
Retrocopy TLLIYTQEW

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1136 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 60 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000001161	1 retrocopy	retro_btau_1020,
Canis familiaris	ENSCAFG00000010685	4 retrocopies	retro_cfam_1120, retro_cfam_1552, retro_cfam_1692, retro_cfam_1837,
Choloepus hoffmanni	ENSCHOG00000007193	17 retrocopies	retro_chof_109, retro_chof_1108, retro_chof_1136 , retro_chof_1255, retro_chof_1614, retro_chof_1689, retro_chof_1770, retro_chof_1971, retro_chof_2126, retro_chof_2493, retro_chof_2576, retro_chof_2587, retro_chof_453, retro_chof_511, retro_chof_856, retro_chof_979, retro_chof_998,
Callithrix jacchus	ENSCJAG00000001215	3 retrocopies	retro_cjac_1072, retro_cjac_3154, retro_cjac_3289,
Felis catus	ENSFCAG00000008955	4 retrocopies	retro_fcat_1311, retro_fcat_1339, retro_fcat_58, retro_fcat_965,
Homo sapiens	ENSG00000139146	3 retrocopies	retro_hsap_1928, retro_hsap_1945, retro_hsap_4029,
Gorilla gorilla	ENSGGOG00000015484	3 retrocopies	retro_ggor_1405, retro_ggor_1415, retro_ggor_2704,
Myotis lucifugus	ENSMLUG00000009827	3 retrocopies	retro_mluc_1663, retro_mluc_1672, retro_mluc_765,
Macaca mulatta	ENSMMUG00000009155	2 retrocopies	retro_mmul_1074, retro_mmul_2324,
Mus musculus	ENSMUSG00000039985	4 retrocopies	retro_mmus_1234, retro_mmus_1471, retro_mmus_1557, retro_mmus_3331,
Nomascus leucogenys	ENSNLEG00000016487	1 retrocopy	retro_nleu_1213,
Oryctolagus cuniculus	ENSOCUG00000008618	1 retrocopy	retro_ocun_1176,
Otolemur garnettii	ENSOGAG00000008927	4 retrocopies	retro_ogar_1253, retro_ogar_1762, retro_ogar_2117, retro_ogar_251,
Pongo abelii	ENSPPYG00000004396	2 retrocopies	retro_pabe_1592, retro_pabe_3309,
Rattus norvegicus	ENSRNOG00000046048	1 retrocopy	retro_rnor_2858,
Rattus norvegicus	ENSRNOG00000049943	2 retrocopies	retro_rnor_1121, retro_rnor_2917,
Sarcophilus harrisii	ENSSHAG00000006261	1 retrocopy	retro_shar_670,
Ictidomys tridecemlineatus	ENSSTOG00000007097	1 retrocopy	retro_itri_16,
Tursiops truncatus	ENSTTRG00000008465	3 retrocopies	retro_ttru_1162, retro_ttru_1498, retro_ttru_984,