RetrogeneDB ID: retro_cpor_22

Retrocopy location

• Organism: Guinea Pig (Cavia porcellus)
• Coordinates: scaffold_14:42196749..42197499(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCPOG00000006064
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCPOG00000003750
• Aliases: None
• Description: 40S ribosomal protein S6 [Source:UniProtKB/TrEMBL;Acc:H0V1L6]

Sequence

>retro_cpor_22
ATGAAGCTGAACATCTCCTTCCCCGCCACTGGCTGCCAGAAACTCATTGAGGTGGATGATGAACGTAAACTTCGTACGTT
CTATGAGAAGCGTATGGCCACAGAAGTTGCTGCTGACTCTCTAGGTGAAGAGTGGAAGGGTTATGTGGTCCGGATCAGTG
GTGGGAACGACAAGCAAGGTTTCCCTATGAAGCAGGGCGTCTTGACTCATGGCCGAGTTCGCTTGCTACTGAGCAAGGGG
CATTCCTGTTATAGACCAAGGAAAACCGGAGAGAGAAAGCGTAAATCTGTCCGAGGTTGCATTGTGGATGCCAATCTGAG
CGTTCTCAACTTGGTTATTGTAAAAAAAGGAGAGAAAGATATTCCTGGATTGACTGATACTACTGTGCGTCGGCGCCTGG
GGCCCAACAGAGCAAGCAGAATCCGCAAACTTTTCAGTCTCTCTAAAGAAGATGATGTTCGCCAATATGTTGTCAGGAAG
CCCTTAAACAAAGAAGGTAAGAAACCCAGGACTAAAGCCCCTAAGATTCAGCGTCTTGTTACTTCGTGTGTCCTCCAACA
CAAGCGCCGCCGTATTGCTCTGAAGAAGCAGCGTAATAAGAAAAACAAAGAGGAGGCTGCAGAATATGCTAAGCTTCTTG
CCAAGAGAATGAAGGAAGCTAAAGAAAAACGCCAGGAACAAATTGCCAAGAGACGTAGGCTTTCCTCTCTGAGAGCTTCT
ACTTCTAAGTCTGAGTCCAATCAGAAATAA

Alignment

ORF - retro_cpor_22 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.79 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADSLGEEWKGYVVRISGGNDKQGFPMKQGVLTH
          MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADSLGEEWKGYVVRISGGNDKQGFPMKQGVLTH
Retrocopy MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADSLGEEWKGYVVRISGGNDKQGFPMKQGVLTH

Parental  GRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASR
          GRVRLLLSKGHSCYRPR.TGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTV.RRLGP.RASR
Retrocopy GRVRLLLSKGHSCYRPRKTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVRRRLGPNRASR

Parental  IRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYA
          IRKLF.LSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVT..VLQHKRRRIALKKQR.KKNKEEAAEYA
Retrocopy IRKLFSLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTSCVLQHKRRRIALKKQRNKKNKEEAAEYA

Parental  KLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK
          KLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSES.QK
Retrocopy KLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESNQK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.40 RPM	155.47 RPM
SRP017611_kidney	0.63 RPM	271.56 RPM
SRP017611_liver	0.22 RPM	140.33 RPM
SRP040447_lung	0.83 RPM	255.36 RPM
SRP040447_skeletal_muscle	0.71 RPM	296.45 RPM

ChIP-Seq

Cavia porcellus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cpor_22 retrocopy.

TSS

Cavia porcellus was not studied using FANTOM5 data.

Lab

retro_cpor_22 was not experimentally validated.

Homology

Retrocopy orthology:

Cavia porcellus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 35 parental genes, and 412 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000017634	1 retrocopy	retro_acar_20,
Ailuropoda melanoleuca	ENSAMEG00000002925	14 retrocopies	retro_amel_1040, retro_amel_1250, retro_amel_1384, retro_amel_1526, retro_amel_1646, retro_amel_1676, retro_amel_189, retro_amel_312, retro_amel_334, retro_amel_382, retro_amel_510, retro_amel_568, retro_amel_657, retro_amel_841,
Canis familiaris	ENSCAFG00000001615	4 retrocopies	retro_cfam_184, retro_cfam_1936, retro_cfam_48, retro_cfam_87,
Choloepus hoffmanni	ENSCHOG00000004622	15 retrocopies	retro_chof_1018, retro_chof_1101, retro_chof_1107, retro_chof_1590, retro_chof_193, retro_chof_2036, retro_chof_2037, retro_chof_2051, retro_chof_2188, retro_chof_2363, retro_chof_2455, retro_chof_2486, retro_chof_2608, retro_chof_849, retro_chof_941,
Callithrix jacchus	ENSCJAG00000020612	6 retrocopies	retro_cjac_1246, retro_cjac_18, retro_cjac_180, retro_cjac_190, retro_cjac_2982, retro_cjac_59,
Cavia porcellus	ENSCPOG00000003750	4 retrocopies	retro_cpor_1244, retro_cpor_22 , retro_cpor_317, retro_cpor_486,
Dasypus novemcinctus	ENSDNOG00000007241	1 retrocopy	retro_dnov_1192,
Dipodomys ordii	ENSDORG00000012057	2 retrocopies	retro_dord_37, retro_dord_452,
Equus caballus	ENSECAG00000016190	5 retrocopies	retro_ecab_175, retro_ecab_312, retro_ecab_603, retro_ecab_771, retro_ecab_861,
Echinops telfairi	ENSETEG00000001584	18 retrocopies	retro_etel_1143, retro_etel_1281, retro_etel_1410, retro_etel_1430, retro_etel_1575, retro_etel_167, retro_etel_1822, retro_etel_188, retro_etel_1964, retro_etel_2004, retro_etel_2041, retro_etel_2194, retro_etel_263, retro_etel_337, retro_etel_378, retro_etel_541, retro_etel_809, retro_etel_825,
Ficedula albicollis	ENSFALG00000003078	1 retrocopy	retro_falb_24,
Felis catus	ENSFCAG00000002541	26 retrocopies	retro_fcat_1082, retro_fcat_1108, retro_fcat_1154, retro_fcat_1262, retro_fcat_1373, retro_fcat_1642, retro_fcat_1679, retro_fcat_1760, retro_fcat_1791, retro_fcat_1934, retro_fcat_1937, retro_fcat_1963, retro_fcat_198, retro_fcat_238, retro_fcat_328, retro_fcat_358, retro_fcat_380, retro_fcat_392, retro_fcat_493, retro_fcat_659, retro_fcat_738, retro_fcat_750, retro_fcat_850, retro_fcat_894, retro_fcat_912, retro_fcat_968,
Homo sapiens	ENSG00000137154	16 retrocopies	retro_hsap_1009, retro_hsap_1067, retro_hsap_1231, retro_hsap_1310, retro_hsap_1967, retro_hsap_2184, retro_hsap_2298, retro_hsap_3045, retro_hsap_3996, retro_hsap_4122, retro_hsap_4235, retro_hsap_4279, retro_hsap_4860, retro_hsap_731, retro_hsap_818, retro_hsap_966,
Gorilla gorilla	ENSGGOG00000002652	13 retrocopies	retro_ggor_1430, retro_ggor_1703, retro_ggor_2097, retro_ggor_2358, retro_ggor_2439, retro_ggor_2769, retro_ggor_2863, retro_ggor_2864, retro_ggor_616, retro_ggor_670, retro_ggor_777, retro_ggor_896, retro_ggor_965,
Loxodonta africana	ENSLAFG00000010766	4 retrocopies	retro_lafr_1021, retro_lafr_1239, retro_lafr_59, retro_lafr_667,
Microcebus murinus	ENSMICG00000007262	24 retrocopies	retro_mmur_1004, retro_mmur_1024, retro_mmur_1048, retro_mmur_1117, retro_mmur_1169, retro_mmur_1298, retro_mmur_1441, retro_mmur_1530, retro_mmur_189, retro_mmur_406, retro_mmur_414, retro_mmur_473, retro_mmur_517, retro_mmur_560, retro_mmur_723, retro_mmur_748, retro_mmur_760, retro_mmur_783, retro_mmur_794, retro_mmur_811, retro_mmur_856, retro_mmur_88, retro_mmur_907, retro_mmur_911,
Myotis lucifugus	ENSMLUG00000007588	27 retrocopies	retro_mluc_1041, retro_mluc_1146, retro_mluc_1169, retro_mluc_1393, retro_mluc_1411, retro_mluc_1448, retro_mluc_1472, retro_mluc_1532, retro_mluc_1566, retro_mluc_1593, retro_mluc_1629, retro_mluc_1635, retro_mluc_1723, retro_mluc_1799, retro_mluc_1909, retro_mluc_1928, retro_mluc_1933, retro_mluc_2110, retro_mluc_2129, retro_mluc_490, retro_mluc_493, retro_mluc_514, retro_mluc_557, retro_mluc_652, retro_mluc_678, retro_mluc_722, retro_mluc_830,
Macaca mulatta	ENSMMUG00000003412	1 retrocopy	retro_mmul_263,
Monodelphis domestica	ENSMODG00000004095	1 retrocopy	retro_mdom_301,
Mus musculus	ENSMUSG00000028495	45 retrocopies	retro_mmus_1010, retro_mmus_1126, retro_mmus_1291, retro_mmus_1357, retro_mmus_1436, retro_mmus_1590, retro_mmus_1663, retro_mmus_1701, retro_mmus_1720, retro_mmus_1966, retro_mmus_1969, retro_mmus_2047, retro_mmus_2068, retro_mmus_2146, retro_mmus_2167, retro_mmus_2171, retro_mmus_2336, retro_mmus_2342, retro_mmus_2367, retro_mmus_2369, retro_mmus_2489, retro_mmus_2546, retro_mmus_2593, retro_mmus_2601, retro_mmus_2625, retro_mmus_2824, retro_mmus_2845, retro_mmus_2946, retro_mmus_3154, retro_mmus_324, retro_mmus_3256, retro_mmus_3338, retro_mmus_3498, retro_mmus_3633, retro_mmus_475, retro_mmus_477, retro_mmus_478, retro_mmus_568, retro_mmus_588, retro_mmus_617, retro_mmus_716, retro_mmus_743, retro_mmus_748, retro_mmus_895, retro_mmus_938,
Nomascus leucogenys	ENSNLEG00000017532	14 retrocopies	retro_nleu_1033, retro_nleu_1333, retro_nleu_1613, retro_nleu_226, retro_nleu_2471, retro_nleu_252, retro_nleu_2536, retro_nleu_2611, retro_nleu_2652, retro_nleu_2655, retro_nleu_2860, retro_nleu_313, retro_nleu_476, retro_nleu_546,
Otolemur garnettii	ENSOGAG00000016254	21 retrocopies	retro_ogar_1208, retro_ogar_1222, retro_ogar_1335, retro_ogar_1356, retro_ogar_1359, retro_ogar_1439, retro_ogar_1526, retro_ogar_1531, retro_ogar_1612, retro_ogar_1979, retro_ogar_2174, retro_ogar_2195, retro_ogar_2248, retro_ogar_2264, retro_ogar_2514, retro_ogar_2707, retro_ogar_2853, retro_ogar_3329, retro_ogar_462, retro_ogar_575, retro_ogar_782,
Ochotona princeps	ENSOPRG00000000751	6 retrocopies	retro_opri_1111, retro_opri_1187, retro_opri_248, retro_opri_33, retro_opri_466, retro_opri_865,
Ochotona princeps	ENSOPRG00000012290	5 retrocopies	retro_opri_123, retro_opri_642, retro_opri_78, retro_opri_862, retro_opri_895,
Pongo abelii	ENSPPYG00000019193	15 retrocopies	retro_pabe_1024, retro_pabe_1625, retro_pabe_2065, retro_pabe_2616, retro_pabe_2617, retro_pabe_2882, retro_pabe_2964, retro_pabe_3282, retro_pabe_3481, retro_pabe_3777, retro_pabe_629, retro_pabe_730, retro_pabe_822, retro_pabe_850, retro_pabe_955,
Pan troglodytes	ENSPTRG00000039153	19 retrocopies	retro_ptro_1313, retro_ptro_1442, retro_ptro_1627, retro_ptro_1662, retro_ptro_1994, retro_ptro_2442, retro_ptro_2713, retro_ptro_2799, retro_ptro_2878, retro_ptro_2902, retro_ptro_2938, retro_ptro_3235, retro_ptro_519, retro_ptro_569, retro_ptro_669, retro_ptro_749, retro_ptro_785, retro_ptro_799, retro_ptro_845,
Rattus norvegicus	ENSRNOG00000007663	21 retrocopies	retro_rnor_1092, retro_rnor_1093, retro_rnor_1269, retro_rnor_1484, retro_rnor_1556, retro_rnor_1564, retro_rnor_1845, retro_rnor_1901, retro_rnor_1991, retro_rnor_2071, retro_rnor_2073, retro_rnor_2187, retro_rnor_2332, retro_rnor_2447, retro_rnor_2781, retro_rnor_2790, retro_rnor_558, retro_rnor_756, retro_rnor_896, retro_rnor_942, retro_rnor_943,
Rattus norvegicus	ENSRNOG00000049025	8 retrocopies	retro_rnor_1008, retro_rnor_1189, retro_rnor_1988, retro_rnor_1990, retro_rnor_2085, retro_rnor_2635, retro_rnor_479, retro_rnor_718,
Sorex araneus	ENSSARG00000006549	6 retrocopies	retro_sara_284, retro_sara_369, retro_sara_392, retro_sara_436, retro_sara_512, retro_sara_710,
Sarcophilus harrisii	ENSSHAG00000005486	1 retrocopy	retro_shar_549,
Sus scrofa	ENSSSCG00000005169	6 retrocopies	retro_sscr_187, retro_sscr_425, retro_sscr_645, retro_sscr_856, retro_sscr_940, retro_sscr_983,
Tupaia belangeri	ENSTBEG00000003474	33 retrocopies	retro_tbel_1380, retro_tbel_1384, retro_tbel_1729, retro_tbel_1747, retro_tbel_1899, retro_tbel_1907, retro_tbel_2051, retro_tbel_2444, retro_tbel_2621, retro_tbel_2753, retro_tbel_2848, retro_tbel_3148, retro_tbel_316, retro_tbel_3165, retro_tbel_3271, retro_tbel_3497, retro_tbel_3591, retro_tbel_3747, retro_tbel_3792, retro_tbel_3866, retro_tbel_3883, retro_tbel_411, retro_tbel_4208, retro_tbel_4242, retro_tbel_4413, retro_tbel_4467, retro_tbel_4570, retro_tbel_485, retro_tbel_492, retro_tbel_576, retro_tbel_743, retro_tbel_824, retro_tbel_828,
Tarsius syrichta	ENSTSYG00000008569	8 retrocopies	retro_tsyr_1048, retro_tsyr_116, retro_tsyr_1521, retro_tsyr_2090, retro_tsyr_347, retro_tsyr_535, retro_tsyr_757, retro_tsyr_87,
Tursiops truncatus	ENSTTRG00000001787	11 retrocopies	retro_ttru_1024, retro_ttru_107, retro_ttru_1275, retro_ttru_370, retro_ttru_468, retro_ttru_587, retro_ttru_748, retro_ttru_786, retro_ttru_878, retro_ttru_905, retro_ttru_934,
Vicugna pacos	ENSVPAG00000006030	10 retrocopies	retro_vpac_217, retro_vpac_228, retro_vpac_288, retro_vpac_297, retro_vpac_392, retro_vpac_407, retro_vpac_412, retro_vpac_438, retro_vpac_618, retro_vpac_70,