RetrogeneDB ID: retro_cfam_1076

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 22:34098210..34099286(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000013284
• Aliases: None
• Description: None

Sequence

>retro_cfam_1076
AGCACGCTCGACTTCCAGCTCGGGGCCCGAGCTGATGGCGAGACCATTCTAAAAGGCCTCCGGTCCGTTTTCCAGGAGCA
AGGGATGACGGAGTCGGTGCACACCTGGCCAGACCATGGTTATCTAGCGACCTACGTAAACAAAAATGGCGGCTTTGCCA
ATTTGAGAATTTACCCACGTGGACTGGTGCTGTTGGATCTTCAGAGCTGCGATGGTGATTCTCAAGGCCAAGAAGTTGAC
AGTCTTTTGAACAAAGTCGAAGAAGGACTGAAAGAATTGAGTGAGGACGGTACTGGGCGGGTGAAGCGATTACCGCCCAT
AGTTCGAGGAGGGGCCGTCGACAGATACTGGCCCGCTGCCGACGGCCGCCTGGTGGAGTAGGACATGGACGAAGTGGTGT
ACGATGAAGATTCACCGTATCAGAACATTAAGATTCTACACTCGAAGCAGTTTGGAAATATCCTTGTCCTCAGTGGGGAT
GTTAATCTGGCGGAGAGTGATCTGGCGTCCACCCAGGCCATCACGGGCAGCGGAAAAGAAGACTACGGTGGCAAAGATGT
ACTGATTCTCGGCGGTGGGGATGGGGGCATATTATGTGAAATAGTCAAACTGAAACCAAGATGGTCACTATGGTAGAGAT
CGACCAAATGGTGATTGATGGGTGTAAGAAATACATGCGGAAAACATGGGGCGACGTCTTAGACGACCTTAAGGGAGACT
GCTATCAGGTTCTGATAGAAGACTGTATCCCGGTACTGGGGAGGTACGCCGAGCAACGGAGAGAGTTTGATTATGTGATC
AATGATTTGACAGCGGTCCCCATCTCCACGTCCCCGGAAGAAGATTCCACATGGGAGTTTCTCAGACTGATTCTTGACCT
CTCAATGAGAGTACTGAAACAGGATGGGGAATACTTTACACAGGGTAACTGTGCGAATTTGACGGAAGCCTTGTCGCTCT
ATGAAGAACAGCTGGGCCGCCTCTATTGTCCTGTGGAATTCTCAAAGGAGATCGTCTGTGTTCCCTCATACTTGGAATTG
TGGGTATTTTACACTGTTTGGAAGAAAGCTAAACCT

Alignment

ORF - retro_cfam_1076 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.67 %
• Parental protein coverage: 97.83 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  TTLPSVSSSPADGETILKGLQSIFQEQGMTESVHTWQDHGYLATYINKNGSFANLRIYPHGLVLLDLQSY
          .TL.......ADGETILKGL.S.FQEQGMTESVHTW.DHGYLATY.NKNG.FANLRIYP.GLVLLDLQS.
Retrocopy STLDFQLGARADGETILKGLRSVFQEQGMTESVHTWPDHGYLATYVNKNGGFANLRIYPRGLVLLDLQSC

Parental  DGDSQGQEVDSLLNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPY
          DGDSQGQEVDSLLNKVEE..KELS.D.TGRVKRLPPIVRGGA.DRYWP.ADGRLVE.D.DEVVYDEDSPY
Retrocopy DGDSQGQEVDSLLNKVEEGLKELSEDGTGRVKRLPPIVRGGAVDRYWPAADGRLVE*DMDEVVYDEDSPY

Parental  QNIKILHSKQFGNILILSGDVNLAESDLAYTQAIMGSGKEDYSGKDVLILGGGDGGILCEIVKLKP-KMV
          QNIKILHSKQFGNIL.LSGDVNLAESDLA.TQAI.GSGKEDY.GKDVLILGGGDGGILCEIVKLKP.KMV
Retrocopy QNIKILHSKQFGNILVLSGDVNLAESDLASTQAITGSGKEDYGGKDVLILGGGDGGILCEIVKLKP<KMV

Parental  TMTCLNIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPIST
          TM....IDQMVIDGCKKYMRKT.GDVLD.LKGDCYQVLIEDCIPVL.RYA...REFDYVINDLTAVPIST
Retrocopy TM--VEIDQMVIDGCKKYMRKTWGDVLDDLKGDCYQVLIEDCIPVLGRYAEQRREFDYVINDLTAVPIST

Parental  SPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLEL
          SPEEDSTWEFLRLILDLSM.VLKQDG.YFTQGNC.NLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLEL
Retrocopy SPEEDSTWEFLRLILDLSMRVLKQDGEYFTQGNCANLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLEL

Parental  WVFYTVWKKAKP
          WVFYTVWKKAKP
Retrocopy WVFYTVWKKAKP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.08 RPM	51.78 RPM
SRP017611_brain	0.08 RPM	41.28 RPM
SRP017611_kidney	0.86 RPM	196.20 RPM
SRP017611_liver	0.07 RPM	19.00 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1076 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1076 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1076 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000018382	1 retrocopy	retro_btau_1412,
Canis familiaris	ENSCAFG00000013284	3 retrocopies	retro_cfam_1076 , retro_cfam_1995, retro_cfam_613,
Callithrix jacchus	ENSCJAG00000033933	1 retrocopy	retro_cjac_518,
Cavia porcellus	ENSCPOG00000006176	2 retrocopies	retro_cpor_729, retro_cpor_889,
Echinops telfairi	ENSETEG00000010098	2 retrocopies	retro_etel_1066, retro_etel_1540,
Homo sapiens	ENSG00000102172	5 retrocopies	retro_hsap_243, retro_hsap_3168, retro_hsap_3193, retro_hsap_3611, retro_hsap_4826,
Gorilla gorilla	ENSGGOG00000003123	3 retrocopies	retro_ggor_1335, retro_ggor_2437, retro_ggor_3009,
Microcebus murinus	ENSMICG00000000192	3 retrocopies	retro_mmur_1421, retro_mmur_1484, retro_mmur_699,
Myotis lucifugus	ENSMLUG00000013185	3 retrocopies	retro_mluc_471, retro_mluc_530, retro_mluc_92,
Macaca mulatta	ENSMMUG00000020392	2 retrocopies	retro_mmul_2003, retro_mmul_2574,
Monodelphis domestica	ENSMODG00000007897	1 retrocopy	retro_mdom_412,
Mus musculus	ENSMUSG00000071708	6 retrocopies	retro_mmus_2162, retro_mmus_2170, retro_mmus_2837, retro_mmus_3502, retro_mmus_3628, retro_mmus_994,
Nomascus leucogenys	ENSNLEG00000009955	4 retrocopies	retro_nleu_1664, retro_nleu_2200, retro_nleu_2208, retro_nleu_2755,
Oryctolagus cuniculus	ENSOCUG00000006016	2 retrocopies	retro_ocun_1458, retro_ocun_1918,
Pongo abelii	ENSPPYG00000020182	4 retrocopies	retro_pabe_2649, retro_pabe_2810, retro_pabe_3752, retro_pabe_38,
Pteropus vampyrus	ENSPVAG00000016785	1 retrocopy	retro_pvam_524,
Rattus norvegicus	ENSRNOG00000007688	2 retrocopies	retro_rnor_1934, retro_rnor_938,
Tupaia belangeri	ENSTBEG00000012109	3 retrocopies	retro_tbel_1630, retro_tbel_1893, retro_tbel_3570,
Vicugna pacos	ENSVPAG00000007543	1 retrocopy	retro_vpac_50,