RetrogeneDB ID: retro_ggor_2404

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:26544190..26544548(-)
• Located in intron of: ENSGGOG00000000743

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000011762
• Aliases: None
• Description: None

Sequence

>retro_ggor_2404
ATGATGAAGTATTCCTAGGCCAGAACAGGCTCCAGAATTTCTAAAACCAAATGTTCACTGCCTTGTGACATTGGTACTCA
AATCCCTATAGCAAACATGCTCTGACCAAAAACGCAGAATATGAGGAGGTGACCCCTGCCCAGAAGCTCCTGTCCCAGTG
ACTCCTGACCAAGACCAGTGGGATGTCCTGCTGGGCTGAGTGGCTATTTCTTGCCAATGATGCTCACCCAGTGTCCACCC
TGGAGGACTCTACTGGGCACCCACAGAATCAGAAGTGACCACCTTCACCTGTAGCATCAACCATGCCCAGCTGATGGTGG
TGGAGGGACAATGTATTTACTGTGTGAACTCTGAGAAC

Alignment

ORF - retro_ggor_2404 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 59.84 %
• Parental protein coverage: 54.79 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MVKY-FLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTNRMPRWAERL
          M.KY.FLGQ..L.....Q.F.A....Y.NPYSKH.LT......EVTP.QKLLS..LLTKT..M..WAE.L
Retrocopy MMKY<FLGQNRLQNF*NQMFTAL*HWYSNPYSKHALTKNAEYEEVTPAQKLLSQ*LLTKTSGMSCWAEWL

Parental  FPANVAHSVYILEDSIVDPQNQ-TMTTFTWNINHARLMVVEERCVYCVNSDN
          F.AN.AH.V..LEDS...PQNQ...TTFT..INHA.LMVVE..C.YCVNS.N
Retrocopy FLANDAHPVSTLEDSTGHPQNQ<EVTTFTCSINHAQLMVVEGQCIYCVNSEN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	14.96 RPM
SRP007412_cerebellum	0.00 RPM	9.02 RPM
SRP007412_heart	0.00 RPM	6.10 RPM
SRP007412_kidney	0.00 RPM	42.77 RPM
SRP007412_liver	0.00 RPM	20.76 RPM
SRP007412_testis	0.00 RPM	6.63 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2404 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2404 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3565
Macaca mulatta	retro_mmul_1822
Callithrix jacchus	retro_cjac_2401

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 81 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005009	2 retrocopies	retro_btau_1727, retro_btau_962,
Canis familiaris	ENSCAFG00000016443	2 retrocopies	retro_cfam_2055, retro_cfam_349,
Choloepus hoffmanni	ENSCHOG00000002251	1 retrocopy	retro_chof_1025,
Callithrix jacchus	ENSCJAG00000006953	5 retrocopies	retro_cjac_1131, retro_cjac_1689, retro_cjac_2401, retro_cjac_3359, retro_cjac_835,
Cavia porcellus	ENSCPOG00000025788	1 retrocopy	retro_cpor_231,
Dasypus novemcinctus	ENSDNOG00000017550	1 retrocopy	retro_dnov_637,
Equus caballus	ENSECAG00000023460	1 retrocopy	retro_ecab_467,
Homo sapiens	ENSG00000169230	7 retrocopies	retro_hsap_1550, retro_hsap_2269, retro_hsap_249, retro_hsap_302, retro_hsap_3518, retro_hsap_3565, retro_hsap_579,
Gorilla gorilla	ENSGGOG00000011762	3 retrocopies	retro_ggor_2404 , retro_ggor_302, retro_ggor_9,
Loxodonta africana	ENSLAFG00000005459	1 retrocopy	retro_lafr_242,
Macropus eugenii	ENSMEUG00000001738	12 retrocopies	retro_meug_1194, retro_meug_1541, retro_meug_1618, retro_meug_1725, retro_meug_1726, retro_meug_2054, retro_meug_274, retro_meug_666, retro_meug_681, retro_meug_854, retro_meug_895, retro_meug_918,
Myotis lucifugus	ENSMLUG00000007008	2 retrocopies	retro_mluc_239, retro_mluc_64,
Macaca mulatta	ENSMMUG00000009046	2 retrocopies	retro_mmul_1822, retro_mmul_2457,
Monodelphis domestica	ENSMODG00000004804	3 retrocopies	retro_mdom_1529, retro_mdom_221, retro_mdom_596,
Mustela putorius furo	ENSMPUG00000012226	1 retrocopy	retro_mputfur_579,
Mus musculus	ENSMUSG00000021486	7 retrocopies	retro_mmus_1316, retro_mmus_2079, retro_mmus_2236, retro_mmus_2394, retro_mmus_2672, retro_mmus_449, retro_mmus_866,
Nomascus leucogenys	ENSNLEG00000012714	5 retrocopies	retro_nleu_1382, retro_nleu_2395, retro_nleu_2400, retro_nleu_803, retro_nleu_857,
Otolemur garnettii	ENSOGAG00000011455	4 retrocopies	retro_ogar_1352, retro_ogar_2025, retro_ogar_3006, retro_ogar_665,
Pongo abelii	ENSPPYG00000016086	7 retrocopies	retro_pabe_1283, retro_pabe_1696, retro_pabe_1699, retro_pabe_2907, retro_pabe_377, retro_pabe_409, retro_pabe_608,
Rattus norvegicus	ENSRNOG00000016410	8 retrocopies	retro_rnor_1138, retro_rnor_1166, retro_rnor_1243, retro_rnor_1906, retro_rnor_2178, retro_rnor_2305, retro_rnor_637, retro_rnor_995,
Sus scrofa	ENSSSCG00000014042	4 retrocopies	retro_sscr_372, retro_sscr_794, retro_sscr_795, retro_sscr_811,
Tupaia belangeri	ENSTBEG00000006445	1 retrocopy	retro_tbel_3855,
Tursiops truncatus	ENSTTRG00000009571	1 retrocopy	retro_ttru_1886,