RetrogeneDB ID: retro_pabe_53

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: X:113358293..113358875(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSPPYG00000020643
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: SSU72
• Ensembl ID: ENSPPYG00000002000
• Aliases: None
• Description: SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25016]

Sequence

>retro_pabe_53
ATGTCATTGTCACCGCTGCGGGTGGCGGTGGTGTGCTGGTGTAACCAGAACCTGAGCATGGAGGCACACAGCGTCCTCAG
CAAACGAGGATTCAGTGTCCAGTCCTTTGGAACAGCACCTCATGTGAAGCTTCCAGGACCAGCGCCTAACAAGCCAAATA
TTTATGATTTCAAAACCACATATGATGAAATGTACAACGATCTTATCACGAAAGACAAAGAATTCTATACACAGAATGGC
GTTCTGCATATGTTAGACAGAAATAAGAGAATCAAGCTCCGGCCGGAAAGGTTCCAGGATTGCAAAGATGTGTTTGATCT
GATCATCACTTGTGAAGAGAGAATTTATGACCAGGTGGTGGAAGATCTAAATTCCAGAGAACAGGAGACCTGCCAACCAG
TGCATGTGGTGAACATGGACATCCAGGACAACCAGGAAGATGCCATCATAGGGGCATTTCTCATCTGCGAGCTCTGCCAG
TGTATCCAGCGCTCAGAGGATATGGAGAATGAGATTGATCAGCTGCTGCAGAAGTTGGAGGAGAAAAGGCGCAAGCCCTT
CCTGCACACGGTCTGCTTCTAC

Alignment

ORF - retro_pabe_53 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.9 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MPSSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLR
          M..SPLRVAVVC..NQN.SMEAH..LSKRGFSV.SFGT..HVKLPGPAP.KPN.YDFKTTYD.MYNDL..
Retrocopy MSLSPLRVAVVCWCNQNLSMEAHSVLSKRGFSVQSFGTAPHVKLPGPAPNKPNIYDFKTTYDEMYNDLIT

Parental  KDKELYTQNGILHMLDRNKRIKPRPE--QNCKDLFDLILTCEERVYDQVV-DLNSREQETCQPVHVVNVD
          KDKE.YTQNG.LHMLDRNKRIK.RPE..Q.CKD.FDLI.TCEER.YDQVV.DLNSREQETCQPVHVVN.D
Retrocopy KDKEFYTQNGVLHMLDRNKRIKLRPERFQDCKDVFDLIITCEERIYDQVVEDLNSREQETCQPVHVVNMD

Parental  IQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRTFLHTVCFY
          IQDN.E.A..GAFLICELCQCIQ..EDMENEID.LLQ..EEK....FLHTVCFY
Retrocopy IQDNQEDAIIGAFLICELCQCIQRSEDMENEIDQLLQKLEEKRRKPFLHTVCFY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	121.09 RPM
SRP007412_cerebellum	0.00 RPM	76.61 RPM
SRP007412_heart	0.00 RPM	30.04 RPM
SRP007412_kidney	0.00 RPM	73.35 RPM
SRP007412_liver	0.00 RPM	65.85 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_53 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_53 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_53 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4741
Pan troglodytes	retro_ptro_3156
Gorilla gorilla	retro_ggor_206
Callithrix jacchus	retro_cjac_37

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 67 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000013736	3 retrocopies	retro_amel_1930, retro_amel_292, retro_amel_84,
Canis familiaris	ENSCAFG00000019254	2 retrocopies	retro_cfam_185, retro_cfam_42,
Callithrix jacchus	ENSCJAG00000010957	3 retrocopies	retro_cjac_1640, retro_cjac_2335, retro_cjac_37,
Cavia porcellus	ENSCPOG00000002238	2 retrocopies	retro_cpor_83, retro_cpor_909,
Dipodomys ordii	ENSDORG00000011714	1 retrocopy	retro_dord_433,
Homo sapiens	ENSG00000160075	8 retrocopies	retro_hsap_3778, retro_hsap_4741, retro_hsap_747, retro_hsap_748, retro_hsap_749, retro_hsap_841, retro_hsap_842, retro_hsap_843,
Gorilla gorilla	ENSGGOG00000004421	1 retrocopy	retro_ggor_206,
Loxodonta africana	ENSLAFG00000002076	4 retrocopies	retro_lafr_1153, retro_lafr_1154, retro_lafr_1155, retro_lafr_400,
Macropus eugenii	ENSMEUG00000015170	1 retrocopy	retro_meug_1253,
Myotis lucifugus	ENSMLUG00000016517	2 retrocopies	retro_mluc_292, retro_mluc_371,
Macaca mulatta	ENSMMUG00000001551	1 retrocopy	retro_mmul_159,
Monodelphis domestica	ENSMODG00000006616	3 retrocopies	retro_mdom_16, retro_mdom_1997, retro_mdom_487,
Mustela putorius furo	ENSMPUG00000014394	2 retrocopies	retro_mputfur_108, retro_mputfur_1408,
Mus musculus	ENSMUSG00000029038	1 retrocopy	retro_mmus_1317,
Otolemur garnettii	ENSOGAG00000024430	2 retrocopies	retro_ogar_124, retro_ogar_13,
Pongo abelii	ENSPPYG00000002000	1 retrocopy	retro_pabe_53 ,
Pan troglodytes	ENSPTRG00000000034	16 retrocopies	retro_ptro_2560, retro_ptro_2963, retro_ptro_3016, retro_ptro_3017, retro_ptro_3018, retro_ptro_3019, retro_ptro_3020, retro_ptro_3021, retro_ptro_3022, retro_ptro_3023, retro_ptro_3024, retro_ptro_3025, retro_ptro_3026, retro_ptro_3156, retro_ptro_531, retro_ptro_532,
Pteropus vampyrus	ENSPVAG00000017695	4 retrocopies	retro_pvam_11, retro_pvam_1151, retro_pvam_272, retro_pvam_767,
Rattus norvegicus	ENSRNOG00000017829	2 retrocopies	retro_rnor_1169, retro_rnor_2766,
Sus scrofa	ENSSSCG00000003348	2 retrocopies	retro_sscr_1179, retro_sscr_38,
Ictidomys tridecemlineatus	ENSSTOG00000002960	4 retrocopies	retro_itri_1055, retro_itri_1352, retro_itri_1496, retro_itri_99,
Tursiops truncatus	ENSTTRG00000017051	2 retrocopies	retro_ttru_1264, retro_ttru_1265,