RetrogeneDB ID: retro_mmus_1317

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 14:123985499..123985816(-)
• Located in intron of: ENSMUSG00000025551

Retrocopy information

• Ensembl ID: ENSMUSG00000082738
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Ssu72
• Ensembl ID: ENSMUSG00000029038
• Aliases: Ssu72, 1190002E22Rik, 1500011L16Rik, 2610101M12Rik
• Description: Ssu72 RNA polymerase II CTD phosphatase homolog (yeast) [Source:MGI Symbol;Acc:MGI:1916241]

Sequence

>retro_mmus_1317
GTGGTATGCTCAAGTAAACAGATTCAGAGCATGAAAGCACACGTCATCCTCAGCAACTGTCATTTCAGTGTCTGTTCCTT
TGGAACAGGAACTATTGATGTTCCCAGGACCAGCAACTGACAAGTCCAATGTTTATGATTTCAAAACTATATATGACCAG
AATGTACAATGATCTCCTCAGGAAAGACAAAGAACTCTATACACAAAATGGAATTTTACATATGTTGGATAGAAATAAAA
GAATCAAGCCCCACCCAGAAAGGTTCCAGAACTTCACAGACCTGTTTGACCTGATCTTCACATGTGAAGAGAATCTC

Alignment

ORF - retro_mmus_1317 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.7 %
• Parental protein coverage: 58.24 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  VVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLP-GPAPDKPNVYDFKTTYDQ-MYNDLLRKDKELYT
          VVCSS.Q..SM.AH.ILS...FSV.SFGTGT....P.GPA.DK.NVYDFKT.YDQ.MYNDLLRKDKELYT
Retrocopy VVCSSKQIQSMKAHVILSNCHFSVCSFGTGT-IDVP>GPATDKSNVYDFKTIYDQ>MYNDLLRKDKELYT

Parental  QNGILHMLDRNKRIKPRPERFQNCTDLFDLILTCEERV
          QNGILHMLDRNKRIKP.PERFQN.TDLFDLI.TCEE..
Retrocopy QNGILHMLDRNKRIKPHPERFQNFTDLFDLIFTCEENL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.19 RPM	26.82 RPM
SRP007412_cerebellum	0.22 RPM	25.10 RPM
SRP007412_heart	0.03 RPM	16.47 RPM
SRP007412_kidney	0.02 RPM	23.27 RPM
SRP007412_liver	0.00 RPM	17.48 RPM
SRP007412_testis	0.05 RPM	9.83 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_1317 was not detected

EST

No EST(s) were mapped for retro_mmus_1317 retrocopy.

TSS

No TSS is located nearby retro_mmus_1317 retrocopy 5' end.

Lab

retro_mmus_1317 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_1317 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Rattus norvegicus	retro_rnor_1169

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 66 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000013736	3 retrocopies	retro_amel_1930, retro_amel_292, retro_amel_84,
Canis familiaris	ENSCAFG00000019254	2 retrocopies	retro_cfam_185, retro_cfam_42,
Callithrix jacchus	ENSCJAG00000010957	3 retrocopies	retro_cjac_1640, retro_cjac_2335, retro_cjac_37,
Cavia porcellus	ENSCPOG00000002238	2 retrocopies	retro_cpor_83, retro_cpor_909,
Homo sapiens	ENSG00000160075	8 retrocopies	retro_hsap_3778, retro_hsap_4741, retro_hsap_747, retro_hsap_748, retro_hsap_749, retro_hsap_841, retro_hsap_842, retro_hsap_843,
Gorilla gorilla	ENSGGOG00000004421	1 retrocopy	retro_ggor_206,
Loxodonta africana	ENSLAFG00000002076	4 retrocopies	retro_lafr_1153, retro_lafr_1154, retro_lafr_1155, retro_lafr_400,
Macropus eugenii	ENSMEUG00000015170	1 retrocopy	retro_meug_1253,
Myotis lucifugus	ENSMLUG00000016517	2 retrocopies	retro_mluc_292, retro_mluc_371,
Macaca mulatta	ENSMMUG00000001551	1 retrocopy	retro_mmul_159,
Monodelphis domestica	ENSMODG00000006616	3 retrocopies	retro_mdom_16, retro_mdom_1997, retro_mdom_487,
Mustela putorius furo	ENSMPUG00000014394	2 retrocopies	retro_mputfur_108, retro_mputfur_1408,
Mus musculus	ENSMUSG00000029038	1 retrocopy	retro_mmus_1317 ,
Otolemur garnettii	ENSOGAG00000024430	2 retrocopies	retro_ogar_124, retro_ogar_13,
Pongo abelii	ENSPPYG00000002000	1 retrocopy	retro_pabe_53,
Pan troglodytes	ENSPTRG00000000034	16 retrocopies	retro_ptro_2560, retro_ptro_2963, retro_ptro_3016, retro_ptro_3017, retro_ptro_3018, retro_ptro_3019, retro_ptro_3020, retro_ptro_3021, retro_ptro_3022, retro_ptro_3023, retro_ptro_3024, retro_ptro_3025, retro_ptro_3026, retro_ptro_3156, retro_ptro_531, retro_ptro_532,
Pteropus vampyrus	ENSPVAG00000017695	4 retrocopies	retro_pvam_11, retro_pvam_1151, retro_pvam_272, retro_pvam_767,
Rattus norvegicus	ENSRNOG00000017829	2 retrocopies	retro_rnor_1169, retro_rnor_2766,
Sus scrofa	ENSSSCG00000003348	2 retrocopies	retro_sscr_1179, retro_sscr_38,
Ictidomys tridecemlineatus	ENSSTOG00000002960	4 retrocopies	retro_itri_1055, retro_itri_1352, retro_itri_1496, retro_itri_99,
Tursiops truncatus	ENSTTRG00000017051	2 retrocopies	retro_ttru_1264, retro_ttru_1265,