RetrogeneDB ID: retro_mmul_1928

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 5:180092572..180093040(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.4290
• Ensembl ID: ENSMMUG00000008776
• Aliases: None
• Description: peroxiredoxin-6 [Source:RefSeq peptide;Acc:NP_001253014]

Sequence

>retro_mmul_1928
ATTGCCCTTTCAATAGACAGTGTTGAGGACCATCTTGCCTGGAGCAAGGATATCAATGCTTACAATGGCGAAGAGCCCAC
AGAAAAGTTACCTTTTCCCATCTTCGATGATAAGAATCGGGACCTTACCATCCTGTTGGCCATGCTGGATCCAGCAGAGA
AGGATGAAAAGGATATGCCTGCGGCGGCTCGTGTGGTGTTTGTTATTGGTCCTGATAAGAAGCCGAAGCTGTCGATCATC
TACCCAGCTACCATTGGCGGGAACTTTGATGACATTCTCCGGTAGTCACCTCTCTGTAGCTGACAGCAGAAAAGAGGGTT
GCCACCCCAGTTGATTGAAAGGATGGGGATAGTGTCATGGTCCTTCCAACCATCCCCGAAGAGGAAGCCAAAAAAACTTT
TTGTGAAAGGAGTCTTCACCAAAGAGCTCCCATCTGGTAAGAAATACCTCCGCTACACACCCTAGCCT

Alignment

ORF - retro_mmul_1928 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 87.34 %
• Parental protein coverage: 69.64 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  IALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDKNRDLAILLGMLDPAEKDEKGMPVTARVVFVFG
          IALSIDSVEDHLAWSKDINAYN.EEPTEKLPFPI.DDKNRDL.ILL.MLDPAEKDEK.MP..ARVVFV.G
Retrocopy IALSIDSVEDHLAWSKDINAYNGEEPTEKLPFPIFDDKNRDLTILLAMLDPAEKDEKDMPAAARVVFVIG

Parental  PDKKLKLSILYPATTGRNFDEILR-VVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEA-KKLFPKGV
          PDKK.KLSI.YPAT.G.NFD.ILR.VV.SL.LTAEKRVATPVD.KDGDSVMVLPTIPEEEA.KKLF.KGV
Retrocopy PDKKPKLSIIYPATIGGNFDDILR<VVTSL*LTAEKRVATPVD*KDGDSVMVLPTIPEEEA>KKLFVKGV

Parental  FTKELPSGKKYLRYTPQP
          FTKELPSGKKYLRYTP.P
Retrocopy FTKELPSGKKYLRYTP*P

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	59.61 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	58.47 RPM
SRP007412_cerebellum	0.00 RPM	48.69 RPM
SRP007412_heart	0.00 RPM	62.24 RPM
SRP007412_kidney	0.12 RPM	228.05 RPM
SRP007412_liver	0.00 RPM	139.89 RPM
SRP007412_testis	0.00 RPM	51.34 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_1928 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_1928 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_1928 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3017
Gorilla gorilla	retro_ggor_2086

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 38 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000015560	1 retrocopy	retro_amel_493,
Bos taurus	ENSBTAG00000004855	2 retrocopies	retro_btau_1325, retro_btau_1477,
Canis familiaris	ENSCAFG00000014579	1 retrocopy	retro_cfam_492,
Choloepus hoffmanni	ENSCHOG00000011367	6 retrocopies	retro_chof_1143, retro_chof_1361, retro_chof_1364, retro_chof_225, retro_chof_2483, retro_chof_2598,
Callithrix jacchus	ENSCJAG00000009355	6 retrocopies	retro_cjac_1903, retro_cjac_2188, retro_cjac_3008, retro_cjac_3239, retro_cjac_3830, retro_cjac_4000,
Cavia porcellus	ENSCPOG00000011091	1 retrocopy	retro_cpor_623,
Equus caballus	ENSECAG00000022468	1 retrocopy	retro_ecab_215,
Erinaceus europaeus	ENSEEUG00000004040	1 retrocopy	retro_eeur_475,
Homo sapiens	ENSG00000117592	2 retrocopies	retro_hsap_1046, retro_hsap_3017,
Gorilla gorilla	ENSGGOG00000026357	1 retrocopy	retro_ggor_2086,
Macaca mulatta	ENSMMUG00000008776	1 retrocopy	retro_mmul_1928 ,
Monodelphis domestica	ENSMODG00000004032	2 retrocopies	retro_mdom_462, retro_mdom_661,
Mustela putorius furo	ENSMPUG00000004648	1 retrocopy	retro_mputfur_1328,
Mus musculus	ENSMUSG00000026701	2 retrocopies	retro_mmus_181, retro_mmus_2334,
Nomascus leucogenys	ENSNLEG00000015278	2 retrocopies	retro_nleu_2244, retro_nleu_917,
Pan troglodytes	ENSPTRG00000042455	1 retrocopy	retro_ptro_70,
Pteropus vampyrus	ENSPVAG00000002596	2 retrocopies	retro_pvam_1389, retro_pvam_805,
Rattus norvegicus	ENSRNOG00000002896	3 retrocopies	retro_rnor_2084, retro_rnor_754, retro_rnor_806,
Sarcophilus harrisii	ENSSHAG00000003248	1 retrocopy	retro_shar_478,
Tursiops truncatus	ENSTTRG00000008478	1 retrocopy	retro_ttru_1274,