RetrogeneDB ID:

retro_hsap_4719

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:X:79815653..79817553(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000228051
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:WBP11
Ensembl ID:ENSG00000084463
Aliases:WBP11, NPWBP, SIPP1, WBP-11
Description:WW domain binding protein 11 [Source:HGNC Symbol;Acc:16461]


Retrocopy-Parental alignment summary:






>retro_hsap_4719
AGATCTACATCATCCACCAAGAGTGGAAACTTTATGAGCCCCATAGACCAAGCCCAAAAGGAAGCCCAGAAGAGAGAATT
GAAGAAGAGCAAAAAACAGCACAAGATGGTTCCAGCTCCAGTTTTAAGGATGAAGGATCCCAAACAGATTATCTGAGACA
TGGAGAAATTGGATGAAATGGAGTTTAACCCAGTATAACAGCCACAATTAAATGAGAAAGTATTAAAAGACAAGCGTAAA
AAGCTGCGTGAAACCTTTGGTATTCTACGACTCTATGAAAAAGAGAATCCAAATATTTACAAAGAACTGAGAAAGCTAGA
AGTAGAGTATAAACAGAAGAGGGCTCAACTTAGCCAATATTTTGATGCCGTCAAGAATGCTCTGCATGTGGAAATGGAGA
GTATTCCTTTGTCAGATATGCCACATATTCCTTCCAACATTTTGATCCAAGACATTCCACTTCCCGGTGCCCATCCACCC
TCCATCCTTAAGAAAACCTCAGCCTATGGACGTCCAACTCGGGCAGTTTCTATCCTGGCTCTTCTTGGACATGGTGTTCC
ACGTTCGCCCCATGGCAGAAAACCTCTTTGCCCTCTCTCTGGCCCACCTCCTTCTCAAGTCGTGCAGATGTACGGCCGTA
AAGTGTGTTTCGCCCTAGATCTTCCCCCATGTAGGCGAGATGAAGACATATTTTATAGTCCTGCACTTGCCCAGAGAGGT
CATGATGATGATGTTTCTAGCACCAGTGAAGATGATGGCTATCCTGAGGACATGGATCAAGATAAGCATGATGAAAGTAC
TGATGACAGTGACACCAACGGATCAGATGGAGAAAGTGAGGAGGATGAATTTGTGCACCATGATGATGGTGAGAGAGACA
ACAATGAAGAAAAGAAGTCAGGTCCTAGTGTACAGTTTGCAAATATGCCTGGAAAATCAAGGAAAAAAAGAAGAACATGA
AGGAACTAACTCCTCTTCAAGCTATGATGCTTCGTATGGCAGGTCAAGAAATCCCTGAGGAGTGATGGGCAGTAGAAGAA
TTTTCAGCGGACGGTGATGAAGATGATTCTGATGACTCTGAAGCAGAAAAGCAATCATAAAAACAGAATAAAGAAGAATC
TCATGCTGATGGCACATCCACTGCTTCTTCATAGCAGCAGGCTCCCCTGAGGTCTGCTCCTCCTTCTCAGATACAAGCAC
CTCCCATGCCAGGACCACCACCTCTTGGACCACCACCTGCTCTACCATTACGGCCTCCTGGGCCACCTACGGGCCTTCCT
CCTGGTCCACCTCCAGGAGCTCCTCCATTACTGAGACCATCTGAAATGCCAGGACTCCAAGGGCCTTTACCCCAACTTTT
ACCTCCAGGACCACCATGAGGCTTGACCCCCTGTCCCTTTCCCAGGTCCAACTGCAGGTATGCCTCCTGGTCCCCCTCCT
TGGGGACCCCCACCAAGAGTACCTCCAGGTATTCCCTCACCTTGTCCCGGCATGATGCGCCCACCTTTGGTGCCTCCCCT
TGGACCTGCCCCCCTGGGTTTTTCCCACCACCTCCCTAGCCGAACCCTGGGGTTTTTTAAGTGCCCCACCCAACTTGATT
CAGCAACCCAAAGCGGATGATATGAGTGCAGCCACGATTGAGAAGAAAGCCACAGCAACCATCAGTGGCAAGTCACAGAT
CAATAATACCAAGGCAGAGATTACTCTACTTCTGCCCACTGCACTGAGAGTTCGTTGGGAGAATAAAGGGGCTACTGCTG
CTCCCCAAAGAAAGTCAGAGGATGATTCTGCTGTGCCTCTTGCCAAAGCAGCACCCAAATCTGGTTCTTCTGTTCCTGTC
TCAGTACAAACTAAGGATGATGTCTATGAGGTTTTCATGAAAGAGATGGAAGGGCTACTC

ORF - retro_hsap_4719 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 80.72 %
Parental protein coverage: 99.53 %
Number of stop codons detected: 9
Number of frameshifts detected: 4


Retrocopy - Parental Gene Alignment:

ParentalRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQL
RSTSSTKSG.FM.P.DQA.KEA.KRELKK.KKQ..MV.A.VL.MKDPKQII.DMEKLDEMEFNPV.QPQL
RetrocopyRSTSSTKSGNFMSPIDQAQKEAQKRELKKSKKQHKMVPAPVLRMKDPKQII*DMEKLDEMEFNPV*QPQL
ParentalNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPD
NEKVLKDKRKKLRETF..ILRLYEKENP.IYKELRKLEVEY.QKRAQLSQYFDAVKNA.HVE.ESIPL.D
RetrocopyNEKVLKDKRKKLRETFG-ILRLYEKENPNIYKELRKLEVEYKQKRAQLSQYFDAVKNALHVEMESIPLSD
ParentalMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQ
MPH.PSNILIQDIPLPGA.PPSILKKTSAYG.PTRAVSIL.LLGHGVPR.P.GRKP..P..GPPP.QVVQ
RetrocopyMPHIPSNILIQDIPLPGAHPPSILKKTSAYGRPTRAVSILALLGHGVPRSPHGRKPLCPLSGPPPSQVVQ
ParentalMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGES
MYGRKV.FALDLPP.RRDED..YSP.LAQRGHDDDVSSTSEDDGYPEDMDQDKHD.STDDSDT..SDGES
RetrocopyMYGRKVCFALDLPPCRRDEDIFYSPALAQRGHDDDVSSTSEDDGYPEDMDQDKHDESTDDSDTNGSDGES
ParentalDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRK-KKKNMKELTPLQAMMLRMAGQEIPEEGREVEEF
..DEFVH.D.GERDNNEEKKSG.SV.FA.MPGKSRK.KKKNMKELTPLQAMMLRMAGQEIPEE...VEEF
RetrocopyEEDEFVHHDDGERDNNEEKKSGPSVQFANMPGKSRK<KKKNMKELTPLQAMMLRMAGQEIPEE*WAVEEF
ParentalSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLR
S.D.DEDDSDDSEAEKQS.KQ.KEESH.DGTSTASS.QQAP..S.PPSQIQAPPMPGPPPLGPPPA.PLR
RetrocopySADGDEDDSDDSEAEKQS*KQNKEESHADGTSTASS*QQAPLRSAPPSQIQAPPMPGPPPLGPPPALPLR
ParentalPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGR-PPGPPPGPPPGLPPGPPPRGPPPRL
...................LRP..MPGL.GPLP.LLPPGPP.G..PP.P.PGP..G.PPGPPP.GPPPR.
RetrocopyXXXXXXXXXXXXXXXXXXLLRPSEMPGLQGPLPQLLPPGPP*GL>PPVPFPGPTAGMPPGPPPWGPPPRV
ParentalPPPAPPGIPPPRPGMMRPPLVPPLGPA-PPGLFPPAPLPNPGVLSAP-PNLIQRP-KADDTSAATIEKKA
PP....GIP.P.PGMMRPPLVPPLGPA.PPG.FPP.P.PNPGV...P.P.....P.KADD.SAATIEKKA
RetrocopyPP----GIPSPCPGMMRPPLVPPLGPA<PPGFFPPPP*PNPGVF*VPHPT*FSNP<KADDMSAATIEKKA
ParentalTATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDD
TATIS.K.QI.N.KAEIT...PTALRVR.ENKGATAAPQRKSEDDSAVPLAKAAPKSG.SVPVSVQTKDD
RetrocopyTATISGKSQINNTKAEITLLLPTALRVRWENKGATAAPQRKSEDDSAVPLAKAAPKSGSSVPVSVQTKDD
ParentalVYEAFMKEMEGLL
VYE.FMKEMEGLL
RetrocopyVYEVFMKEMEGLL

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 0 .00 RPM 80 .66 RPM
bodymap2_adrenal 0 .00 RPM 87 .18 RPM
bodymap2_brain 0 .00 RPM 91 .25 RPM
bodymap2_breast 0 .00 RPM 59 .48 RPM
bodymap2_colon 0 .00 RPM 58 .47 RPM
bodymap2_heart 0 .00 RPM 62 .42 RPM
bodymap2_kidney 0 .00 RPM 62 .37 RPM
bodymap2_liver 0 .00 RPM 25 .39 RPM
bodymap2_lung 0 .00 RPM 68 .92 RPM
bodymap2_lymph_node 0 .00 RPM 59 .06 RPM
bodymap2_ovary 0 .00 RPM 82 .52 RPM
bodymap2_prostate 0 .00 RPM 70 .08 RPM
bodymap2_skeletal_muscle 0 .00 RPM 88 .50 RPM
bodymap2_testis 0 .00 RPM 144 .45 RPM
bodymap2_thyroid 0 .00 RPM 125 .91 RPM
bodymap2_white_blood_cells 0 .00 RPM 108 .15 RPM

ChIP-Seq - click to see more details

RNA Polymerase II activity near the 5' end of retro_hsap_4719 was not detected

EST - click to see more details

No EST(s) were mapped for retro_hsap_4719 retrocopy.

TSS - click to see more details

No TSS is located nearby retro_hsap_4719 retrocopy 5' end.

Lab - click to see more details

retro_hsap_4719 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_4719 has 1 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Gorilla gorilla retro_ggor_2932
Parental genes homology:
Parental genes homology involve 22 parental genes, and 34 retrocopies.

Species Parental gene accession Retrocopies number
Bos taurus ENSBTAG000000147591 retrocopy
retro_btau_20,
Canis familiaris ENSCAFG000000129262 retrocopies
retro_cfam_1369, retro_cfam_1911,
Callithrix jacchus ENSCJAG000000216111 retrocopy
retro_cjac_1737,
Homo sapiens ENSG00000084463 2 retrocopies
retro_hsap_1878, retro_hsap_4719 ,
Gorilla gorilla ENSGGOG000000044483 retrocopies
retro_ggor_1375, retro_ggor_1711, retro_ggor_2932,
Macropus eugenii ENSMEUG000000139711 retrocopy
retro_meug_1952,
Myotis lucifugus ENSMLUG000000152161 retrocopy
retro_mluc_1074,
Macaca mulatta ENSMMUG000000192991 retrocopy
retro_mmul_1329,
Monodelphis domestica ENSMODG000000179491 retrocopy
retro_mdom_143,
Mustela putorius furoENSMPUG000000116191 retrocopy
retro_mputfur_280,
Mus musculus ENSMUSG000000302161 retrocopy
retro_mmus_2740,
Nomascus leucogenys ENSNLEG000000039261 retrocopy
retro_nleu_2651,
Oryctolagus cuniculus ENSOCUG000000171771 retrocopy
retro_ocun_974,
Otolemur garnettii ENSOGAG000000105181 retrocopy
retro_ogar_207,
Ochotona princeps ENSOPRG000000150083 retrocopies
retro_opri_107, retro_opri_1159, retro_opri_678,
Pongo abelii ENSPPYG000000043233 retrocopies
retro_pabe_1558, retro_pabe_2099, retro_pabe_3663,
Pan troglodytes ENSPTRG000000047243 retrocopies
retro_ptro_1260, retro_ptro_1637, retro_ptro_3136,
Rattus norvegicus ENSRNOG000000055053 retrocopies
retro_rnor_1287, retro_rnor_2726, retro_rnor_741,
Rattus norvegicus ENSRNOG000000495931 retrocopy
retro_rnor_740,
Sorex araneus ENSSARG000000070851 retrocopy
retro_sara_753,
Sarcophilus harrisii ENSSHAG000000166491 retrocopy
retro_shar_81,
Tupaia belangeri ENSTBEG000000033941 retrocopy
retro_tbel_2213,

Expression level across human populations :

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