RetrogeneDB ID: retro_ggor_985

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 13:19967806..19968939(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HSPD1
• Ensembl ID: ENSGGOG00000008267
• Aliases: None
• Description: None

Sequence

>retro_ggor_985
AGAGAGGTTGCCATCACAGTAAAGGAGGGAAAAAACACTGAATGATGAATTAGACATTATTGAAGACCTGAAGTTTGATT
GAGGATATATTTCTCCATACTTTATTAATATACCAGAAGGCTAGAAATGTGAATTCCAGGATGCCCATGTTCTAATGAGT
GAATAGAAAATTTCTAGTGCCCAGTCCATTGTACCTGCTCTTGAAGTTGCCAATGCTCACCATAAAACTTTGGTCATAAT
TGTTGAAGATATTCATGGAGAAGCTCTAAGTACATTCGTTTTGAATAGGCTAAAAGTTGGTCTTCACATTATAGCAGTCA
AAGCTCCAGGATTTGATGAACAATTGAAAGAACCAGCTTAAAGATTTGGCTATTGCTACTGGTGGTGCAGTGTTTGGAGA
CGAGGGCTTGGCCCTAAATCTTGAATATGTGCAGCCTTGTGACTTAGGTAAAGTTGGAGAGGTCATTGTGACTAAAGATT
ATGCTATGCTCTTAAAAGGAAAAGGTGACAAGTCTCAAATTGAAAAAAAAATTCAAGAAATCATGGAGCAGTTAGATGTC
ACAATTAGTGATACGAAAAGGAAAAACTGATAGAATGGCTGGAAAACTTTTCAGATGGAGTACCTGTGCTGAAGGTTGGT
GGGACAAGTGATGTCAAAGTGAATGAAAAGAAAGACAGAGTTACAGATCCCTTAATGCTACAATAACTGCCGTTGAAGAA
GGCATTGTTCTGGGAAGGGGCTGTGCCCTGCTTCAATACGTTCCAGCCTTGTACTCATTGACTCCAGCTAGTGAAGATCA
AAACATTGGTATAGAAATTAAAAGAATATTCAAAATTTCTGCAATGACAATTGCTAAAAATGCAGGTATTGAAGGATCTT
TTATAGTCAAGAAAATTACACAAAGTTCTATAGAAGTTGGTTATGATGCTATGGTCAGAGATTTTGTGAATATGGTGGGA
AAAGGAATCATTGATCCAACAAAGTTTGTGAAAACTGTTTTATTGGATGCTTTTGGGTGGCCTCTCTGTTAACTACAGCA
GAAATTTTAGTCACAAAAATTCCTGAAGAAGAGAAGGACCCTGGAATGGGTGCAATATGTAGAATGAGAGCTGGTATGAG
AGGTGGCATGTTC

Alignment

ORF - retro_ggor_985 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.3 %
• Parental protein coverage: 66.08 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  RKGVITVKDGK-TLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEI
          R...ITVK.GK.TLNDEL.IIE..KFD.GYISPYFIN...G.KCEFQDA.VL.SE.KISS.QSIVPALE.
Retrocopy REVAITVKEGK>TLNDELDIIEDLKFD*GYISPYFINIPEG*KCEFQDAHVLMSE*KISSAQSIVPALEV

Parental  ANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGD-NRKNQLKDMAIATGGAVFGEEGLTL
          ANAH.K.LVII.ED..GEALST.VLNRLKVGL...AVKAPGF...N.KNQLKD.AIATGGAVFG.EGL.L
Retrocopy ANAHHKTLVIIVEDIHGEALSTFVLNRLKVGLHIIAVKAPGFDE>N*KNQLKDLAIATGGAVFGDEGLAL

Parental  NLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSE-YEKEKLNERLAKLSDGV
          NLE.VQP.DLGKVGEVIVTKD.AMLLKGKGDK.QI....QEI.EQLDVT.S..YEKEKL.E.L...SDGV
Retrocopy NLEYVQPCDLGKVGEVIVTKDYAMLLKGKGDKSQIXXXXQEIMEQLDVTISD<YEKEKLIEWLENFSDGV

Parental  AVLKVGGTSDVEVNEKKDRVTD-ALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKR
          .VLKVGGTSDV.VNEKKDRVTD..LNAT..AVEEGIVLG.GCALL...PAL.SLTPA.EDQ.IGIE.IKR
Retrocopy PVLKVGGTSDVKVNEKKDRVTD<SLNATITAVEEGIVLGRGCALLQYVPALYSLTPASEDQNIGIE-IKR

Parental  TLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAG-VASLL
          ..KI.AMTIAKNAG.EGS.IV.KI.QSS.EVGYDAM..DFVNMV.KGIIDPTK.V.T.LLDA.G.VASLL
Retrocopy IFKISAMTIAKNAGIEGSFIVKKITQSSIEVGYDAMVRDFVNMVGKGIIDPTKFVKTVLLDAFG<VASLL

Parental  TTAEVVVTEIPKEEKDPGMGA-GGMGGGMGGGMF
          TTAE..VT.IP.EEKDPGMGA...M..GM.GGMF
Retrocopy TTAEILVTKIPEEEKDPGMGAICRMRAGMRGGMF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	103.01 RPM
SRP007412_cerebellum	0.00 RPM	73.16 RPM
SRP007412_heart	0.00 RPM	38.90 RPM
SRP007412_kidney	0.04 RPM	335.53 RPM
SRP007412_liver	0.00 RPM	169.79 RPM
SRP007412_testis	0.00 RPM	151.67 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_985 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_985 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 74 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000013770	1 retrocopy	retro_amel_771,
Canis familiaris	ENSCAFG00000010865	4 retrocopies	retro_cfam_1185, retro_cfam_1620, retro_cfam_2165, retro_cfam_614,
Callithrix jacchus	ENSCJAG00000003990	6 retrocopies	retro_cjac_1516, retro_cjac_1534, retro_cjac_1975, retro_cjac_3172, retro_cjac_3400, retro_cjac_4096,
Echinops telfairi	ENSETEG00000009184	4 retrocopies	retro_etel_1440, retro_etel_426, retro_etel_885, retro_etel_925,
Homo sapiens	ENSG00000144381	7 retrocopies	retro_hsap_1006, retro_hsap_2770, retro_hsap_2987, retro_hsap_3151, retro_hsap_3494, retro_hsap_3930, retro_hsap_4018,
Gorilla gorilla	ENSGGOG00000008267	6 retrocopies	retro_ggor_1927, retro_ggor_2069, retro_ggor_2361, retro_ggor_2698, retro_ggor_800, retro_ggor_985 ,
Loxodonta africana	ENSLAFG00000000053	1 retrocopy	retro_lafr_476,
Macropus eugenii	ENSMEUG00000011987	2 retrocopies	retro_meug_1688, retro_meug_224,
Myotis lucifugus	ENSMLUG00000000871	4 retrocopies	retro_mluc_1458, retro_mluc_2280, retro_mluc_2348, retro_mluc_601,
Macaca mulatta	ENSMMUG00000010489	1 retrocopy	retro_mmul_83,
Monodelphis domestica	ENSMODG00000012289	3 retrocopies	retro_mdom_427, retro_mdom_493, retro_mdom_756,
Mustela putorius furo	ENSMPUG00000007818	3 retrocopies	retro_mputfur_1118, retro_mputfur_245, retro_mputfur_434,
Mus musculus	ENSMUSG00000025980	5 retrocopies	retro_mmus_1225, retro_mmus_2494, retro_mmus_3206, retro_mmus_439, retro_mmus_706,
Nomascus leucogenys	ENSNLEG00000006874	7 retrocopies	retro_nleu_1349, retro_nleu_2238, retro_nleu_229, retro_nleu_657, retro_nleu_675, retro_nleu_691, retro_nleu_787,
Otolemur garnettii	ENSOGAG00000034053	5 retrocopies	retro_ogar_2335, retro_ogar_2420, retro_ogar_2740, retro_ogar_3221, retro_ogar_3497,
Pongo abelii	ENSPPYG00000013046	5 retrocopies	retro_pabe_2040, retro_pabe_2244, retro_pabe_2476, retro_pabe_2887, retro_pabe_848,
Rattus norvegicus	ENSRNOG00000014525	9 retrocopies	retro_rnor_1000, retro_rnor_1006, retro_rnor_1308, retro_rnor_1578, retro_rnor_1585, retro_rnor_2812, retro_rnor_2835, retro_rnor_596, retro_rnor_905,
Xenopus tropicalis	ENSXETG00000007509	1 retrocopy	retro_xtro_63,