RetrogeneDB ID: retro_ggor_2858

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 9:54312709..54313158(-)
• Located in intron of: ENSGGOG00000011002

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS27A
• Ensembl ID: ENSGGOG00000007678
• Aliases: None
• Description: None

Sequence

>retro_ggor_2858
TTAAAAACCCTTATGGGAAAGACCATCACTCTGGAGTTTGAACCCTTGGATACAATAGAAAATGCAAAGTCCAAGATCTA
GGATAAGACAGGAATTTCTACTGATCAGCAAAGACTGATCTTTGCTGGCAAGAAACTGGAAGATGGATGTGCTTTGTCTG
GGTACAACATTCAAAAGGAGTCTACTCTTCATCTTGTGTTGAGACTTCATGGTGGTGCTAAGAAAAGGAAGAAGTCTTAC
ACCACTCCAAAGAAGAATAAGCATAAGAAAAGGAAGGTAAGCTGGCTGTCCTGAAATACTATAAGGTGGATGAAAATGGC
AAAATTAGTCAACTTCATCAAGAATGCCCTTCGGATTAATGTATTGCTGGAGATTTTGTGGCCAGCCATTTTAACAGTCA
TTGTTGTAGCAAATGTCTGCACTATTGTTTCAACAAACCAGAAGACAAG

Alignment

ORF - retro_ggor_2858 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.08 %
• Parental protein coverage: 97.44 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  VKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR
          .KTL.GKTITLE.EP.DTIEN.K.KI.DK.GI..DQQRLIFAGK.LEDG..LS.YNIQKESTLHLVLRL.
Retrocopy LKTLMGKTITLEFEPLDTIENAKSKI*DKTGISTDQQRLIFAGKKLEDGCALSGYNIQKESTLHLVLRLH

Parental  GGAKKRKKKSYTTPKKNKHKRKKV-KLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGK
          GGAKKR.KKSYTTPKKNKHK..KV.KLAVLKYYKVDENGKIS.L..ECPSD.C.AG.F.ASHF..H.C.K
Retrocopy GGAKKR-KKSYTTPKKNKHKKRKV<KLAVLKYYKVDENGKISQLHQECPSD*CIAGDFVASHFNSHCCSK

Parental  CCLTYCFNKPEDK
          .CL.YCFNKPEDK
Retrocopy -CLHYCFNKPEDK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	105.69 RPM
SRP007412_cerebellum	0.00 RPM	133.52 RPM
SRP007412_heart	0.00 RPM	62.04 RPM
SRP007412_kidney	0.00 RPM	336.07 RPM
SRP007412_liver	0.00 RPM	334.68 RPM
SRP007412_testis	0.00 RPM	172.39 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2858 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2858 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4272
Macaca mulatta	retro_mmul_1198

---

Parental genes homology:

Parental genes homology involve 28 parental genes, and 256 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004017	5 retrocopies	retro_amel_1565, retro_amel_175, retro_amel_598, retro_amel_661, retro_amel_844,
Bos taurus	ENSBTAG00000015473	6 retrocopies	retro_btau_1115, retro_btau_1213, retro_btau_1631, retro_btau_395, retro_btau_440, retro_btau_664,
Canis familiaris	ENSCAFG00000023471	3 retrocopies	retro_cfam_1048, retro_cfam_640, retro_cfam_81,
Callithrix jacchus	ENSCJAG00000010052	5 retrocopies	retro_cjac_200, retro_cjac_229, retro_cjac_344, retro_cjac_74, retro_cjac_88,
Cavia porcellus	ENSCPOG00000005819	7 retrocopies	retro_cpor_1040, retro_cpor_1433, retro_cpor_406, retro_cpor_409, retro_cpor_502, retro_cpor_591, retro_cpor_990,
Dasypus novemcinctus	ENSDNOG00000004813	12 retrocopies	retro_dnov_131, retro_dnov_1340, retro_dnov_1432, retro_dnov_1558, retro_dnov_1664, retro_dnov_2022, retro_dnov_2183, retro_dnov_2576, retro_dnov_2635, retro_dnov_491, retro_dnov_538, retro_dnov_771,
Dipodomys ordii	ENSDORG00000006291	11 retrocopies	retro_dord_114, retro_dord_13, retro_dord_372, retro_dord_396, retro_dord_430, retro_dord_472, retro_dord_478, retro_dord_549, retro_dord_584, retro_dord_662, retro_dord_737,
Equus caballus	ENSECAG00000018773	3 retrocopies	retro_ecab_341, retro_ecab_748, retro_ecab_776,
Erinaceus europaeus	ENSEEUG00000002329	9 retrocopies	retro_eeur_127, retro_eeur_143, retro_eeur_193, retro_eeur_283, retro_eeur_289, retro_eeur_308, retro_eeur_58, retro_eeur_629, retro_eeur_72,
Felis catus	ENSFCAG00000023939	1 retrocopy	retro_fcat_1542,
Gorilla gorilla	ENSGGOG00000007678	9 retrocopies	retro_ggor_1290, retro_ggor_1291, retro_ggor_1502, retro_ggor_1749, retro_ggor_179, retro_ggor_203, retro_ggor_2373, retro_ggor_2858 , retro_ggor_2885,
Loxodonta africana	ENSLAFG00000023133	2 retrocopies	retro_lafr_1122, retro_lafr_185,
Macropus eugenii	ENSMEUG00000008917	13 retrocopies	retro_meug_107, retro_meug_1184, retro_meug_1460, retro_meug_1514, retro_meug_1544, retro_meug_1657, retro_meug_183, retro_meug_1866, retro_meug_209, retro_meug_521, retro_meug_594, retro_meug_937, retro_meug_94,
Myotis lucifugus	ENSMLUG00000017064	10 retrocopies	retro_mluc_1201, retro_mluc_1255, retro_mluc_1298, retro_mluc_1646, retro_mluc_1730, retro_mluc_1865, retro_mluc_1867, retro_mluc_2264, retro_mluc_37, retro_mluc_380,
Myotis lucifugus	ENSMLUG00000029449	1 retrocopy	retro_mluc_1585,
Monodelphis domestica	ENSMODG00000001819	3 retrocopies	retro_mdom_1367, retro_mdom_1751, retro_mdom_205,
Mustela putorius furo	ENSMPUG00000010468	6 retrocopies	retro_mputfur_1512, retro_mputfur_242, retro_mputfur_319, retro_mputfur_332, retro_mputfur_499, retro_mputfur_777,
Oryctolagus cuniculus	ENSOCUG00000003613	10 retrocopies	retro_ocun_1087, retro_ocun_1163, retro_ocun_1209, retro_ocun_1259, retro_ocun_1268, retro_ocun_1339, retro_ocun_164, retro_ocun_288, retro_ocun_381, retro_ocun_851,
Ochotona princeps	ENSOPRG00000010469	13 retrocopies	retro_opri_1056, retro_opri_1120, retro_opri_162, retro_opri_177, retro_opri_191, retro_opri_331, retro_opri_472, retro_opri_490, retro_opri_582, retro_opri_71, retro_opri_717, retro_opri_801, retro_opri_871,
Pongo abelii	ENSPPYG00000025871	1 retrocopy	retro_pabe_117,
Pan troglodytes	ENSPTRG00000011928	1 retrocopy	retro_ptro_32,
Pteropus vampyrus	ENSPVAG00000016471	3 retrocopies	retro_pvam_1052, retro_pvam_676, retro_pvam_952,
Rattus norvegicus	ENSRNOG00000004426	2 retrocopies	retro_rnor_117, retro_rnor_161,
Sus scrofa	ENSSSCG00000022357	1 retrocopy	retro_sscr_145,
Ictidomys tridecemlineatus	ENSSTOG00000009566	5 retrocopies	retro_itri_1583, retro_itri_1765, retro_itri_26, retro_itri_635, retro_itri_962,
Tupaia belangeri	ENSTBEG00000004626	95 retrocopies	retro_tbel_1019, retro_tbel_1022, retro_tbel_1057, retro_tbel_1058, retro_tbel_106, retro_tbel_1081, retro_tbel_1086, retro_tbel_1090, retro_tbel_1134, retro_tbel_1255, retro_tbel_1385, retro_tbel_1403, retro_tbel_1459, retro_tbel_1493, retro_tbel_1565, retro_tbel_1566, retro_tbel_157, retro_tbel_1584, retro_tbel_1606, retro_tbel_1623, retro_tbel_1673, retro_tbel_1678, retro_tbel_1760, retro_tbel_1825, retro_tbel_1863, retro_tbel_1902, retro_tbel_1946, retro_tbel_1952, retro_tbel_2067, retro_tbel_2119, retro_tbel_2122, retro_tbel_2123, retro_tbel_2238, retro_tbel_2354, retro_tbel_2408, retro_tbel_2605, retro_tbel_2671, retro_tbel_2739, retro_tbel_283, retro_tbel_2913, retro_tbel_2939, retro_tbel_2952, retro_tbel_3056, retro_tbel_3119, retro_tbel_3120, retro_tbel_3125, retro_tbel_3180, retro_tbel_3183, retro_tbel_3213, retro_tbel_3258, retro_tbel_3260, retro_tbel_3283, retro_tbel_3389, retro_tbel_3446, retro_tbel_3480, retro_tbel_3481, retro_tbel_3505, retro_tbel_3576, retro_tbel_3595, retro_tbel_3621, retro_tbel_3649, retro_tbel_3665, retro_tbel_3831, retro_tbel_3839, retro_tbel_3840, retro_tbel_3874, retro_tbel_3920, retro_tbel_396, retro_tbel_3977, retro_tbel_4021, retro_tbel_4053, retro_tbel_4133, retro_tbel_4149, retro_tbel_4224, retro_tbel_426, retro_tbel_4284, retro_tbel_4305, retro_tbel_4313, retro_tbel_4474, retro_tbel_4484, retro_tbel_4498, retro_tbel_4499, retro_tbel_4502, retro_tbel_4504, retro_tbel_4547, retro_tbel_4554, retro_tbel_4565, retro_tbel_4628, retro_tbel_703, retro_tbel_709, retro_tbel_763, retro_tbel_843, retro_tbel_866, retro_tbel_871, retro_tbel_874,
Tarsius syrichta	ENSTSYG00000000845	14 retrocopies	retro_tsyr_107, retro_tsyr_122, retro_tsyr_1379, retro_tsyr_1493, retro_tsyr_1520, retro_tsyr_1877, retro_tsyr_1890, retro_tsyr_1892, retro_tsyr_1950, retro_tsyr_2121, retro_tsyr_339, retro_tsyr_767, retro_tsyr_855, retro_tsyr_879,
Tursiops truncatus	ENSTTRG00000013947	5 retrocopies	retro_ttru_1199, retro_ttru_1279, retro_ttru_533, retro_ttru_705, retro_ttru_838,