RetrogeneDB ID: retro_ggor_2437

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:70296089..70297139(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000003123
• Aliases: None
• Description: None

Sequence

>retro_ggor_2437
GCTGATGGTGAGACTGTTCTAAAAGGCCTCCAGTCCATTTTCCAGGAGCAGGGGACGGCAGAGTCGGTGCACACCTGGCA
GGACCATGGCTATTTAGCAACCTACACAAAAAAGAACGGCAGCTTTGCCAATTTGAGAATTTACCCACATGGATTGGTGT
TGCTGGACCTTCAGAGTTATGATGGTGATGTGCAAGGCAAAGAAGAGATCGACAGTATTTTGAACAAAGTAGAAGAAAGA
ATGAAAGAATTGAGTCAGGACAGTACTGGGCGGGTGAAACGATTACCACCCATAGTGCGAGGAGGAGCCATTGACAGATA
TTGGCTCACCGCCGATGGGCGCCTGGTTGAATATGACATAGATGAAGTGGTATATGACAAAGATTAATCTTATCAAAATA
TAAAAATTCTACACTCGAAGCAGTTTGGAAATATTCTCATCCTTAGTGGGGATGTTAATTTGGCAGAGAGTGATTTGGCA
TATACCCGGTCCATCATGGGCAGTGGCGAAGAAGATTACACTGGCAAAGATGTACTCATTCTGGGAGGTGGAGATGGAGG
CATATTGTGTGAAATAGTCAAACTAAAACCAAAGATGGTCACTACGGTAGAGATTGACCAAATGGTGATTGATGGGTGTA
AGAAATACATGCAAAAAACGTGTGGCGATGTCTTAGACAATCTTAAAGGAGACTGCTATCAGGTTCTAATAGAAGACTGT
ATTCCGGTACTGAAGAGGTACGCCAAAGAAGGGAGATAATTTGATTATGTGATTAATGATTTGACAGCTGTTCCAATCTC
CACTTCTCCAGAAGAAGATTCCACATGGGAGTTTCTCAGACTGATTCTTGACCTCTCAATGAAAGTGTTGAAACAGGATG
GGAAATATTTTACACAGGGGAACTGTGTCAGTCTGACAGAAGCGCTGTCGCTCTATGAAGAACAGCCGGGGCGCCTGTAT
TGTCCTGTGGAATTTTCAAAGGAGATTCTCTGTGTCCCTTCATACTTGGAATCGTGGGTATTTTACACTGTTTGGAAGAA
AGCTAAACCC

Alignment

ORF - retro_ggor_2437 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.03 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  ADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLRIYPHGLVLLDLQSYDGDAQGKEEI
          ADGET.LKGLQSIFQEQG.AESVHTWQDHGYLATYT.KNGSFANLRIYPHGLVLLDLQSYDGD.QGKEEI
Retrocopy ADGETVLKGLQSIFQEQGTAESVHTWQDHGYLATYTKKNGSFANLRIYPHGLVLLDLQSYDGDVQGKEEI

Parental  DSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSK
          DSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYW.TADGRLVEYDIDEVVYD.D..YQNIKILHSK
Retrocopy DSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYWLTADGRLVEYDIDEVVYDKD*SYQNIKILHSK

Parental  QFGNILILSGDVNLAESDLAYTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMPVADIDQM
          QFGNILILSGDVNLAESDLAYTR.IMGSG.EDYTGKDVLILGGGDGGILCEIVKLKPKMVT.....IDQM
Retrocopy QFGNILILSGDVNLAESDLAYTRSIMGSGEEDYTGKDVLILGGGDGGILCEIVKLKPKMVT--TVEIDQM

Parental  VIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF
          VIDGCKKYM.KTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGR.FDYVINDLTAVPISTSPEEDSTWEF
Retrocopy VIDGCKKYMQKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGR*FDYVINDLTAVPISTSPEEDSTWEF

Parental  LRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKA
          LRLILDLSMKVLKQDGKYFTQGNCV.LTEALSLYEEQ.GRLYCPVEFSKEI.CVPSYLE.WVFYTVWKKA
Retrocopy LRLILDLSMKVLKQDGKYFTQGNCVSLTEALSLYEEQPGRLYCPVEFSKEILCVPSYLESWVFYTVWKKA

Parental  KP
          KP
Retrocopy KP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	5.66 RPM	59.65 RPM
SRP007412_cerebellum	4.18 RPM	53.11 RPM
SRP007412_heart	1.50 RPM	19.42 RPM
SRP007412_kidney	4.33 RPM	69.27 RPM
SRP007412_liver	1.32 RPM	20.07 RPM
SRP007412_testis	4.04 RPM	58.84 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2437 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2437 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3611
Pongo abelii	retro_pabe_38

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000018382	1 retrocopy	retro_btau_1412,
Canis familiaris	ENSCAFG00000013284	3 retrocopies	retro_cfam_1076, retro_cfam_1995, retro_cfam_613,
Callithrix jacchus	ENSCJAG00000033933	1 retrocopy	retro_cjac_518,
Cavia porcellus	ENSCPOG00000006176	2 retrocopies	retro_cpor_729, retro_cpor_889,
Echinops telfairi	ENSETEG00000010098	2 retrocopies	retro_etel_1066, retro_etel_1540,
Homo sapiens	ENSG00000102172	5 retrocopies	retro_hsap_243, retro_hsap_3168, retro_hsap_3193, retro_hsap_3611, retro_hsap_4826,
Gorilla gorilla	ENSGGOG00000003123	3 retrocopies	retro_ggor_1335, retro_ggor_2437 , retro_ggor_3009,
Microcebus murinus	ENSMICG00000000192	3 retrocopies	retro_mmur_1421, retro_mmur_1484, retro_mmur_699,
Myotis lucifugus	ENSMLUG00000013185	3 retrocopies	retro_mluc_471, retro_mluc_530, retro_mluc_92,
Macaca mulatta	ENSMMUG00000020392	2 retrocopies	retro_mmul_2003, retro_mmul_2574,
Monodelphis domestica	ENSMODG00000007897	1 retrocopy	retro_mdom_412,
Mus musculus	ENSMUSG00000071708	6 retrocopies	retro_mmus_2162, retro_mmus_2170, retro_mmus_2837, retro_mmus_3502, retro_mmus_3628, retro_mmus_994,
Nomascus leucogenys	ENSNLEG00000009955	4 retrocopies	retro_nleu_1664, retro_nleu_2200, retro_nleu_2208, retro_nleu_2755,
Oryctolagus cuniculus	ENSOCUG00000006016	2 retrocopies	retro_ocun_1458, retro_ocun_1918,
Pongo abelii	ENSPPYG00000020182	4 retrocopies	retro_pabe_2649, retro_pabe_2810, retro_pabe_3752, retro_pabe_38,
Pteropus vampyrus	ENSPVAG00000016785	1 retrocopy	retro_pvam_524,
Rattus norvegicus	ENSRNOG00000007688	2 retrocopies	retro_rnor_1934, retro_rnor_938,
Tupaia belangeri	ENSTBEG00000012109	3 retrocopies	retro_tbel_1630, retro_tbel_1893, retro_tbel_3570,
Vicugna pacos	ENSVPAG00000007543	1 retrocopy	retro_vpac_50,