RetrogeneDB ID: retro_nleu_333

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397263.1:47778351..47779217(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSNLEG00000007056
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: EIF3E
• Ensembl ID: ENSNLEG00000004120
• Aliases: None
• Description: Eukaryotic translation initiation factor 3 subunit E [Source:UniProtKB/TrEMBL;Acc:G1QVT7]

Sequence

>retro_nleu_333
ACAGACTCCCTTTTCTTTGGCAAGATGGCGGAGTACGACTTGACTACTCGCATCGCGCACTTTTTGGATCGGCATCTAGT
CTTTCGGCTTCTTGAGTTTCTCTCTGTAAAGGAGATATATAATGAAAAGGAATTATTACAAGGTAAATTGGACCTTCTTT
TTTACACCGACATGGTAGACTTTGCTATGGATGTATACAAAAACCTTTATTCTGATGATATTCCTCATGCTTTGAGAGAG
AAAAGAACCACAGTGGTTGCACAACTGAAACAGCTTCAGGCAGAAACAGAACCAATTGTGAAGATGTTTGAAGATCCAGA
AACTACAAGGCAAATGCAGTCAACCAGGGATGGTAGGATGCTCTTTGACTACCTGGCGGACAAACATGGTTTTAGGCAGT
AATATTTAGATACCCTCTACAGATATGCAAAATTCCAGTACGAATGTGGGAATTACTCAGGAGCAGCAGAATATCTTTAT
TTTTTTAGAGTGCTGGTTCCAGCAACAGATAGAAATGCTTTAAGTTCACTCTGGGGAAAGCTGGCCTCTGAAATCTTAAT
GCAGAATTGGGATGCAGCCATGGAAGACCTTACACGGTTAAAAGAGACCATAGATAATAATTCTGTGAGTTCTCCACTTC
AGTCTCTTCAGCAGAGAACATGGCTCATTCACTAGTCTCTGTTTTCTTCAATCACCCCAAAGGTCGCGATAATATTATTG
ACCTCTTCCTTTATCAGCCACAATATCTTCATGCAATTCAGACAATGTGTCCACACATTCTTCGCTATCTGACTACAGCA
GTCATAACAAACAAGGATGTTCGAAAACGTCGGCAGGTTCTAAAAGATCTAGTTAAAGTTATTCAA

Alignment

ORF - retro_nleu_333 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.53 %
• Parental protein coverage: 58.47 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  TDSLFFGKMAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLY
          TDSLFFGKMAEYDLTTRIAHFLDRHLVF.LLEFLSVKEIYNEKELLQGKLDLL..T.MVDFAMDVYKNLY
Retrocopy TDSLFFGKMAEYDLTTRIAHFLDRHLVFRLLEFLSVKEIYNEKELLQGKLDLLFYTDMVDFAMDVYKNLY

Parental  SDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLY
          SDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQ.YLDTLY
Retrocopy SDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQ*YLDTLY

Parental  RYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVS
          RYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVS
Retrocopy RYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVS

Parental  SPLQSLQQRTWLIHWSLFVFFNHPK-GRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRR
          SPLQSLQQRTWLIH.SLF.....PK.GRDNIIDLFLYQPQYL.AIQTMCPHILRYLTTAVITNKDVRKRR
Retrocopy SPLQSLQQRTWLIH*SLFSSIT-PK<GRDNIIDLFLYQPQYLHAIQTMCPHILRYLTTAVITNKDVRKRR

Parental  QVLKDLVKVIQ
          QVLKDLVKVIQ
Retrocopy QVLKDLVKVIQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_333 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000006702	1 retrocopy	retro_btau_291,
Canis familiaris	ENSCAFG00000000702	1 retrocopy	retro_cfam_1127,
Callithrix jacchus	ENSCJAG00000006458	3 retrocopies	retro_cjac_2333, retro_cjac_2686, retro_cjac_701,
Equus caballus	ENSECAG00000000236	1 retrocopy	retro_ecab_860,
Echinops telfairi	ENSETEG00000013105	1 retrocopy	retro_etel_2048,
Felis catus	ENSFCAG00000003665	1 retrocopy	retro_fcat_231,
Homo sapiens	ENSG00000104408	1 retrocopy	retro_hsap_3489,
Gorilla gorilla	ENSGGOG00000022955	2 retrocopies	retro_ggor_2354, retro_ggor_2355,
Myotis lucifugus	ENSMLUG00000007269	1 retrocopy	retro_mluc_1796,
Macaca mulatta	ENSMMUG00000011359	1 retrocopy	retro_mmul_2585,
Mustela putorius furo	ENSMPUG00000005924	2 retrocopies	retro_mputfur_193, retro_mputfur_736,
Mus musculus	ENSMUSG00000022336	2 retrocopies	retro_mmus_1801, retro_mmus_2807,
Nomascus leucogenys	ENSNLEG00000004120	1 retrocopy	retro_nleu_333 ,
Oryctolagus cuniculus	ENSOCUG00000008050	1 retrocopy	retro_ocun_1399,
Pan troglodytes	ENSPTRG00000020505	1 retrocopy	retro_ptro_2362,
Rattus norvegicus	ENSRNOG00000027690	4 retrocopies	retro_rnor_1133, retro_rnor_2879, retro_rnor_583, retro_rnor_584,
Ictidomys tridecemlineatus	ENSSTOG00000008976	1 retrocopy	retro_itri_545,
Tursiops truncatus	ENSTTRG00000011025	2 retrocopies	retro_ttru_1602, retro_ttru_1794,