RetrogeneDB ID: retro_mmul_2018

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 6:74446273..74446524(+)
• Located in intron of: ENSMMUG00000001360

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.9909
• Ensembl ID: ENSMMUG00000004899
• Aliases: None
• Description: V-type proton ATPase subunit G 1 [Source:RefSeq peptide;Acc:NP_001180531]

Sequence

>retro_mmul_2018
AGGTTGCTGAAAAGGGTGTCTGAGACCTGCAGTGAAAGAAACGGAGGCAGAAGCAGACCAAAGCAGCAGCTCAAGGTGAA
ATTGAATAATATTGCCTGCAAAGGCAGAAAGAGTTCAAGGCCAAGGAGGCTGCTGCCCTGGGATCCCAAGGCAGCTGCAG
CACTAAAGTAGAGGAGACCCAGTAGAAGAGAACCATCCGGAAGTAGTTTAGGCAGAAGAGGGGTGAAGTCTTGGCCTTCT
TCTGCGACATC

Alignment

ORF - retro_mmul_2018 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 62.64 %
• Parental protein coverage: 76.27 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  RAAEKVSEARKRKN-RRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSTEVEKETQEKMTILQ
          R....VSE.....N.RR.KQ.K..AQ.EIE.Y.LQR.KEFKAKEAAALGS.GSCST.VE.ETQ.K.TI..
Retrocopy RLLKRVSETCSERN<RRQKQTKAAAQGEIE*YCLQRQKEFKAKEAAALGSQGSCSTKVE-ETQ*KRTI-R

Parental  TYFRQNRDEVLDNLLAFVCDI
          ..FRQ.R.EVL....AF.CDI
Retrocopy K*FRQKRGEVL----AFFCDI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	23.98 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	25.86 RPM
SRP007412_cerebellum	0.00 RPM	23.89 RPM
SRP007412_heart	0.00 RPM	22.73 RPM
SRP007412_kidney	0.00 RPM	36.50 RPM
SRP007412_liver	0.00 RPM	10.37 RPM
SRP007412_testis	0.08 RPM	44.70 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2018 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2018 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2018 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3198
Pan troglodytes	retro_ptro_2248
Gorilla gorilla	retro_ggor_1331

---

Parental genes homology:

Parental genes homology involve 27 parental genes, and 89 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012509	3 retrocopies	retro_amel_1053, retro_amel_376, retro_amel_999,
Callithrix jacchus	ENSCJAG00000020461	3 retrocopies	retro_cjac_1788, retro_cjac_2513, retro_cjac_76,
Cavia porcellus	ENSCPOG00000000763	5 retrocopies	retro_cpor_1523, retro_cpor_204, retro_cpor_688, retro_cpor_742, retro_cpor_852,
Dasypus novemcinctus	ENSDNOG00000008083	15 retrocopies	retro_dnov_1173, retro_dnov_1447, retro_dnov_1475, retro_dnov_1504, retro_dnov_1588, retro_dnov_1645, retro_dnov_193, retro_dnov_1998, retro_dnov_2179, retro_dnov_218, retro_dnov_2416, retro_dnov_245, retro_dnov_336, retro_dnov_479, retro_dnov_790,
Dipodomys ordii	ENSDORG00000014850	5 retrocopies	retro_dord_434, retro_dord_466, retro_dord_614, retro_dord_640, retro_dord_749,
Equus caballus	ENSECAG00000011155	1 retrocopy	retro_ecab_816,
Echinops telfairi	ENSETEG00000008080	3 retrocopies	retro_etel_350, retro_etel_594, retro_etel_996,
Felis catus	ENSFCAG00000000160	2 retrocopies	retro_fcat_1614, retro_fcat_402,
Homo sapiens	ENSG00000136888	3 retrocopies	retro_hsap_3198, retro_hsap_4049, retro_hsap_763,
Gorilla gorilla	ENSGGOG00000004011	4 retrocopies	retro_ggor_1331, retro_ggor_2215, retro_ggor_2717, retro_ggor_632,
Loxodonta africana	ENSLAFG00000013437	2 retrocopies	retro_lafr_1002, retro_lafr_39,
Microcebus murinus	ENSMICG00000015368	3 retrocopies	retro_mmur_1217, retro_mmur_1259, retro_mmur_755,
Myotis lucifugus	ENSMLUG00000008657	2 retrocopies	retro_mluc_373, retro_mluc_839,
Macaca mulatta	ENSMMUG00000004899	4 retrocopies	retro_mmul_1783, retro_mmul_2018 , retro_mmul_2046, retro_mmul_331,
Monodelphis domestica	ENSMODG00000019574	1 retrocopy	retro_mdom_1675,
Mustela putorius furo	ENSMPUG00000001653	3 retrocopies	retro_mputfur_1338, retro_mputfur_922, retro_mputfur_994,
Mus musculus	ENSMUSG00000039105	5 retrocopies	retro_mmus_2028, retro_mmus_2784, retro_mmus_2787, retro_mmus_3316, retro_mmus_819,
Nomascus leucogenys	ENSNLEG00000016833	2 retrocopies	retro_nleu_1151, retro_nleu_3045,
Oryctolagus cuniculus	ENSOCUG00000026252	3 retrocopies	retro_ocun_1411, retro_ocun_368, retro_ocun_639,
Otolemur garnettii	ENSOGAG00000010103	3 retrocopies	retro_ogar_1824, retro_ogar_2822, retro_ogar_342,
Pan troglodytes	ENSPTRG00000021290	2 retrocopies	retro_ptro_2248, retro_ptro_2744,
Pteropus vampyrus	ENSPVAG00000008334	1 retrocopy	retro_pvam_1432,
Rattus norvegicus	ENSRNOG00000008163	2 retrocopies	retro_rnor_1246, retro_rnor_676,
Ictidomys tridecemlineatus	ENSSTOG00000015857	5 retrocopies	retro_itri_1102, retro_itri_1235, retro_itri_1281, retro_itri_1340, retro_itri_1669,
Tupaia belangeri	ENSTBEG00000010985	2 retrocopies	retro_tbel_2147, retro_tbel_786,
Tarsius syrichta	ENSTSYG00000011474	3 retrocopies	retro_tsyr_1865, retro_tsyr_2141, retro_tsyr_614,
Tursiops truncatus	ENSTTRG00000015203	2 retrocopies	retro_ttru_125, retro_ttru_480,