RetrogeneDB ID: retro_mmul_1606

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 3:60174815..60175709(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.2317
• Ensembl ID: ENSMMUG00000000535
• Aliases: None
• Description: None

Sequence

>retro_mmul_1606
AGATCTGAGTGGGACATACTTTTGAAGGATGTGCAATGTTCAATCATAAGTGTGACAAAAACTGATAAGCAGGAAGCTTA
TGTACTCAGTGAGAGTAGCATGTTTGTCTCCAAGAGACGTTTCATTCTGAAGACATGTGGTACCACCCTCTTGCTGAAAG
CACTGGTTCCCCTGTTGAAACTTGCTAGGGATTACAGTGGGTTTGACTCAATTCAAAGCTTCTTTTATTCTCATAAGAAT
TTCATGAAGTCTTATCACAAAGTGTACCCACACCAGAATTTCCAGGAAGAAATAGAGTTTCTTAATGCAATCTTCCCAAA
TGGAACAGCATATTGTATGGAACGTATGAATTCTGTCTGTTGGTACTTACATACTCTGGATTTCCCAGAGAGTCGGGTAA
TCAGTCAGCCAGATCAAACCTTGAAAATTCTGATGAGTGAGCTTGACCCAGCAGTTATGGACCAGTTCTACATGAAAGAT
GGTGTTATTGCAAAGGATGTCACTCGTGAGAGTGGAATTCGTGACCTGATACCGGCTTCTGTCATTGATGCCACAATGTT
CAATCCTTGTGGGTATTCAGTGAATGGGATGAAATTGGATGGAACTTATCGGACTATTCACATCAACTCCAGAAACAGAA
TTTTCTTATGTTAGCTTTGAAACACACTTAAATCAGACCTCGTAGGAAGACCTGGTCAGGAAAGTTGTAGAAGTCTTCAA
GCCAGGAGAATTTGTGACCACCTTGTTTGGTTATCAGAGTTCTAAATGTCGCACAGAGCTTGCTTCGCCCCAGAAGATAG
AAGGTTTTAAGCATCTTGATTGCCAGAGTGCTATGTTCAATGATTACAATTGTGTTTTTATCAGTTTTGCTAAGAACAGC
AACAACATCAGAGT

Alignment

ORF - retro_mmul_1606 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.67 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  RSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDS
          RSEWD.LLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDS
Retrocopy RSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDS

Parental  IQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQT
          IQSFFYS.KNFMK..H..YPH.NFQEEIEFLNAIFPNG.AYCM.RMNS.CWYL.TLDFPESRVISQPDQT
Retrocopy IQSFFYSHKNFMKSYHKVYPHQNFQEEIEFLNAIFPNGTAYCMERMNSVCWYLHTLDFPESRVISQPDQT

Parental  LEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHI-T
          L.ILMSELDPAVMDQFYMKDGV.AKDVTRESGIRDLIP.SVIDATMFNPCGYS.NGMK.DGTY.TIHI.T
Retrocopy LKILMSELDPAVMDQFYMKDGVIAKDVTRESGIRDLIPASVIDATMFNPCGYSVNGMKLDGTYRTIHI>T

Parental  PEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMF
          PE.EFSYVSFET.L.QTS..DL.RKVVEVFKPG.FVTTLF..QSSKCRT.LASPQKIEGFK.LDCQSAMF
Retrocopy PETEFSYVSFETHLNQTS*EDLVRKVVEVFKPGEFVTTLFGYQSSKCRTELASPQKIEGFKHLDCQSAMF

Parental  NDYNFVFTSFAK-KQQQQQS
          NDYN.VF.SFAK..QQQ.QS
Retrocopy NDYNCVFISFAK<EQQQHQS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.45 RPM	45.94 RPM
SRP007412_brain_prefrontal_cortex	0.56 RPM	35.46 RPM
SRP007412_cerebellum	0.45 RPM	42.94 RPM
SRP007412_heart	0.53 RPM	12.66 RPM
SRP007412_kidney	0.94 RPM	40.14 RPM
SRP007412_liver	0.24 RPM	7.64 RPM
SRP007412_testis	0.26 RPM	14.47 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_1606 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_1606 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_1606 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 87 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003500	1 retrocopy	retro_amel_797,
Bos taurus	ENSBTAG00000003342	1 retrocopy	retro_btau_1545,
Canis familiaris	ENSCAFG00000003905	2 retrocopies	retro_cfam_1526, retro_cfam_2056,
Choloepus hoffmanni	ENSCHOG00000009171	9 retrocopies	retro_chof_1327, retro_chof_2200, retro_chof_238, retro_chof_2691, retro_chof_332, retro_chof_425, retro_chof_628, retro_chof_74, retro_chof_968,
Callithrix jacchus	ENSCJAG00000005257	6 retrocopies	retro_cjac_1600, retro_cjac_1738, retro_cjac_2452, retro_cjac_3020, retro_cjac_631, retro_cjac_850,
Dasypus novemcinctus	ENSDNOG00000006867	10 retrocopies	retro_dnov_1736, retro_dnov_1796, retro_dnov_185, retro_dnov_2436, retro_dnov_2653, retro_dnov_315, retro_dnov_357, retro_dnov_63, retro_dnov_752, retro_dnov_770,
Equus caballus	ENSECAG00000011198	4 retrocopies	retro_ecab_1110, retro_ecab_173, retro_ecab_57, retro_ecab_681,
Felis catus	ENSFCAG00000028033	1 retrocopy	retro_fcat_1175,
Homo sapiens	ENSG00000123505	5 retrocopies	retro_hsap_3315, retro_hsap_3630, retro_hsap_3922, retro_hsap_4917, retro_hsap_547,
Gorilla gorilla	ENSGGOG00000006466	5 retrocopies	retro_ggor_1304, retro_ggor_2448, retro_ggor_2640, retro_ggor_3070, retro_ggor_498,
Loxodonta africana	ENSLAFG00000013203	2 retrocopies	retro_lafr_1040, retro_lafr_770,
Macropus eugenii	ENSMEUG00000010630	1 retrocopy	retro_meug_1558,
Myotis lucifugus	ENSMLUG00000005666	4 retrocopies	retro_mluc_1675, retro_mluc_1687, retro_mluc_2625, retro_mluc_538,
Macaca mulatta	ENSMMUG00000000535	6 retrocopies	retro_mmul_1606 , retro_mmul_1742, retro_mmul_1841, retro_mmul_2076, retro_mmul_2383, retro_mmul_2648,
Mus musculus	ENSMUSG00000075232	1 retrocopy	retro_mmus_47,
Nomascus leucogenys	ENSNLEG00000012818	4 retrocopies	retro_nleu_2758, retro_nleu_2983, retro_nleu_720, retro_nleu_812,
Otolemur garnettii	ENSOGAG00000030150	7 retrocopies	retro_ogar_1108, retro_ogar_1152, retro_ogar_1608, retro_ogar_1962, retro_ogar_3163, retro_ogar_354, retro_ogar_366,
Pongo abelii	ENSPPYG00000016924	4 retrocopies	retro_pabe_2977, retro_pabe_3194, retro_pabe_3826, retro_pabe_505,
Pan troglodytes	ENSPTRG00000018501	5 retrocopies	retro_ptro_2157, retro_ptro_2453, retro_ptro_2667, retro_ptro_3280, retro_ptro_411,
Rattus norvegicus	ENSRNOG00000000585	1 retrocopy	retro_rnor_1050,
Sorex araneus	ENSSARG00000014387	3 retrocopies	retro_sara_274, retro_sara_614, retro_sara_760,
Sus scrofa	ENSSSCG00000004392	1 retrocopy	retro_sscr_1042,
Ictidomys tridecemlineatus	ENSSTOG00000000205	4 retrocopies	retro_itri_1402, retro_itri_1859, retro_itri_598, retro_itri_943,