RetrogeneDB ID: retro_ecab_377

Retrocopy location

• Organism: Horse (Equus caballus)
• Coordinates: 16:37386066..37386678(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPL14
• Ensembl ID: ENSECAG00000026813
• Aliases: None
• Description: ribosomal protein L14 [Source:HGNC Symbol;Acc:10305]

Sequence

>retro_ecab_377
TTCATGGAGGTTGGCTGGGTGACCTACGTCTCCTTTGGGCCTCATGCAGGGAAGCTGGTTGCGACTGTAGATGTTATTGA
TCAGAACAGGACTTTGGTCGATGGTCCTTGCACTCAGGTGAGGAGACAAGCTATGTCTTTTAAATACATGCAGCTCACTG
ACTTCATCCTATAGTTTCCACACAGTGCCCGCCAGAAGTACATCCAACAAGCCTGGCAGAAGGCAGATATCAATACAAAC
TGGGCAACCACAAGATGGGCCAAGAAGATGGAAGCCAGAAAAAGGAAAGCCAAGATGACAGATTTTGATGGTTTTAAAGT
CATGAAGGCAAAGAAAATGAAGAACAGAATAATCAAGTTTGAAGTCAGGAAGCCTCAAAAGGAAGGTCTCCTGAAAGCTT
CTCCCAAGAAATAATCTGCTGCTAAGGGTGCAGCTGCAACAACTGCTGCAGAGGTTCCAGCAAAAAAGATGACTGCTGTG
GGCCAGAAGGCTCCAGCCCGGAAGGTTCCTGCCAAGAAAGCTGCAGGCCAGAAGACAGCACCTCTGAAAGCTCAGAATGG
TCAGACAGCTCCAGCCCAGAGAGCACCTGCTCCAAAGGCGTCTGGCAAGAAA

Alignment

ORF - retro_ecab_377 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 77.94 %
• Parental protein coverage: 95.33 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  FVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRQ
          F.EVG.V.YVSFGPHAGKLVA.VDVIDQNR.LVDGPCTQVRRQAM.FK.MQLTDFIL.FPHSARQKY..Q
Retrocopy FMEVGWVTYVSFGPHAGKLVATVDVIDQNRTLVDGPCTQVRRQAMSFKYMQLTDFIL*FPHSARQKYIQQ

Parental  AWQKADINTKWAATRWAKKIEARERKPKMTDFDRYKVMKAKKMRNRIIKLEVRKLQKAALLKASPKKAPA
          AWQKADINT.WA.TRWAKK.EAR.RK.KMTDFD..KVMKAKKM.NRIIK.EVRK.QK..LLKASPKK..A
Retrocopy AWQKADINTNWATTRWAKKMEARKRKAKMTDFDGFKVMKAKKMKNRIIKFEVRKPQKEGLLKASPKK*SA

Parental  AKGAAATAAAKVPSKKTTTAGKKAPAQKAPAQKAAGQKAAPPKAQKGQKAPGQKTPAQKAPAPK
          AKGAAAT.AA.VP.KK.T..G.KAPA.K.PA.KAAGQK.AP.KAQ.GQ.AP.Q..PA.KA...K
Retrocopy AKGAAATTAAEVPAKKMTAVGQKAPARKVPAKKAAGQKTAPLKAQNGQTAPAQRAPAPKASGKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP021940_articular_cartilage	2.07 RPM	1213.95 RPM
SRP021940_cerebellum	1.30 RPM	479.28 RPM
SRP021940_embryo	1.61 RPM	666.71 RPM
SRP021940_placental_villous	1.78 RPM	454.55 RPM
SRP021940_synovial_membrane	1.40 RPM	506.05 RPM
SRP021940_testis	11.51 RPM	136.90 RPM

ChIP-Seq

Equus caballus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ecab_377 retrocopy.

TSS

Equus caballus was not studied using FANTOM5 data.

Lab

retro_ecab_377 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ecab_377 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 27 parental genes, and 88 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001709	4 retrocopies	retro_amel_1876, retro_amel_1933, retro_amel_296, retro_amel_660,
Canis familiaris	ENSCAFG00000005138	1 retrocopy	retro_cfam_31,
Callithrix jacchus	ENSCJAG00000017884	9 retrocopies	retro_cjac_1249, retro_cjac_1393, retro_cjac_1835, retro_cjac_2138, retro_cjac_2139, retro_cjac_2332, retro_cjac_2797, retro_cjac_3240, retro_cjac_630,
Cavia porcellus	ENSCPOG00000000711	1 retrocopy	retro_cpor_529,
Equus caballus	ENSECAG00000026813	2 retrocopies	retro_ecab_377 , retro_ecab_743,
Echinops telfairi	ENSETEG00000012894	6 retrocopies	retro_etel_2117, retro_etel_2155, retro_etel_251, retro_etel_315, retro_etel_356, retro_etel_387,
Felis catus	ENSFCAG00000015655	4 retrocopies	retro_fcat_1000, retro_fcat_1457, retro_fcat_587, retro_fcat_671,
Homo sapiens	ENSG00000188846	6 retrocopies	retro_hsap_1015, retro_hsap_1047, retro_hsap_2796, retro_hsap_3104, retro_hsap_3352, retro_hsap_4777,
Gorilla gorilla	ENSGGOG00000025958	3 retrocopies	retro_ggor_122, retro_ggor_1945, retro_ggor_2272,
Latimeria chalumnae	ENSLACG00000015639	1 retrocopy	retro_lcha_29,
Microcebus murinus	ENSMICG00000009217	4 retrocopies	retro_mmur_1218, retro_mmur_1352, retro_mmur_279, retro_mmur_3,
Myotis lucifugus	ENSMLUG00000014429	4 retrocopies	retro_mluc_1294, retro_mluc_2263, retro_mluc_420, retro_mluc_563,
Monodelphis domestica	ENSMODG00000015262	2 retrocopies	retro_mdom_1499, retro_mdom_1939,
Mustela putorius furo	ENSMPUG00000017961	1 retrocopy	retro_mputfur_90,
Mus musculus	ENSMUSG00000025794	3 retrocopies	retro_mmus_2904, retro_mmus_2929, retro_mmus_3011,
Nomascus leucogenys	ENSNLEG00000005682	2 retrocopies	retro_nleu_763, retro_nleu_918,
Oryctolagus cuniculus	ENSOCUG00000010309	3 retrocopies	retro_ocun_410, retro_ocun_464, retro_ocun_656,
Pan troglodytes	ENSPTRG00000011963	4 retrocopies	retro_ptro_1893, retro_ptro_2100, retro_ptro_2135, retro_ptro_713,
Pteropus vampyrus	ENSPVAG00000013914	7 retrocopies	retro_pvam_1108, retro_pvam_1413, retro_pvam_246, retro_pvam_446, retro_pvam_683, retro_pvam_903, retro_pvam_904,
Rattus norvegicus	ENSRNOG00000019007	4 retrocopies	retro_rnor_2268, retro_rnor_2620, retro_rnor_415, retro_rnor_591,
Sorex araneus	ENSSARG00000003974	2 retrocopies	retro_sara_349, retro_sara_504,
Sarcophilus harrisii	ENSSHAG00000001591	5 retrocopies	retro_shar_397, retro_shar_539, retro_shar_696, retro_shar_737, retro_shar_788,
Sus scrofa	ENSSSCG00000011272	2 retrocopies	retro_sscr_521, retro_sscr_63,
Ictidomys tridecemlineatus	ENSSTOG00000021460	1 retrocopy	retro_itri_946,
Tarsius syrichta	ENSTSYG00000002161	5 retrocopies	retro_tsyr_1036, retro_tsyr_1404, retro_tsyr_176, retro_tsyr_361, retro_tsyr_956,
Tursiops truncatus	ENSTTRG00000006708	1 retrocopy	retro_ttru_113,
Xenopus tropicalis	ENSXETG00000022018	1 retrocopy	retro_xtro_3,