RetrogeneDB ID: retro_chof_2206

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_58243:3428..4166(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: IGBP1
• Ensembl ID: ENSCHOG00000013654
• Aliases: None
• Description: immunoglobulin (CD79A) binding protein 1 [Source:HGNC Symbol;Acc:5461]

Sequence

>retro_chof_2206
CGAAATGAAGACCTGGAGGAGATTGCTTCCAGCGACCTGAAGTACCTGATGGTGCCGGCATTTCAAGGAGCTCTCACCAT
GAAACAAGTCAGCCCCAGCAAGTGTCTGGGTCATTTGCAGCAGGCTCGAGAACACTTTCTAAACTACTTAACTCAGTGCC
ATTATTATCATGTGGCAGAATTTGAACTGCCCCAAATCAAGAACAACTCTGCTGAAAATAACACTGCGAGCTCTTCTGTG
GCTTATCCTAGCCTTGTTGCTATGGCCTTTCAAAGACAGGCTAAGATAGAGAGATACAAGCAGCAGAAGGAGATAGAGCA
CAGATTATCTACCCTGAAACCTTCTGTGGAAAGTGGCGAAGCAGACGACGAGCGTGTTCGTGAGTATTATCACCTTCACC
TTCAGAGGTGGATTGGCATCAGCTTGGAAGAGATTGAGAGTATTGATCAATAGATAAAGATTCTAAGAGAAAAAGACTCC
TCAAAAGAGGCATCAACTTCTCGTTCATCTCTTCAGGACAGGCGTCCAGTAAAGCCTTTCATTCTCACCCGGGATGTGGC
CCAAGCCAAGGTGTTTGGAGCTGGTTATCCAAGTCTGGCAACCATGACAGTGAGTGACTGGTATGATCAGCAACGGAAAT
ACGGGGCATTACCAGATCAGGGAATCGCCAAGACAACACCAGCAGAATTCAAAAAGGCACCTCAAAAACAGGAAGATCAG
GAGCCAAAGGAGGAGGAC

Alignment

ORF - retro_chof_2206 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.74 %
• Parental protein coverage: 97.98 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  RNEDLEEIASTDLKYLMVPAYQGALTMKQVNPSKRLDHLQQAREHFLNYLTQCHYYHVAEFELPKIKNNS
          RNEDLEEIAS.DLKYLMVPA.QGALTMKQV.PSK.L.HLQQAREHFLNYLTQCHYYHVAEFELP.IKNNS
Retrocopy RNEDLEEIASSDLKYLMVPAFQGALTMKQVSPSKCLGHLQQAREHFLNYLTQCHYYHVAEFELPQIKNNS

Parental  AENNTASSSMTYPSLVAMASQRQAKIERYKQKEE--HRLST-KTSVESGEADDERVREYYLLHLQWWIGI
          AENNTASSS..YPSLVAMA.QRQAKIERYKQ..E..HRLST.K.SVESGEADDERVREYY.LHLQ.WIGI
Retrocopy AENNTASSSVAYPSLVAMAFQRQAKIERYKQQKEIEHRLSTLKPSVESGEADDERVREYYHLHLQRWIGI

Parental  SLEEIESIDHEIKILRKKDSSKEASTSRSSLQDRPPMKPFILTRDVAQAKVFGAGYPSLATMTVNDWYEQ
          SLEEIESID..IKILR.KDSSKEASTSRSSLQDR.P.KPFILTRDVAQAKVFGAGYPSLATMTV.DWY.Q
Retrocopy SLEEIESIDQ*IKILREKDSSKEASTSRSSLQDRRPVKPFILTRDVAQAKVFGAGYPSLATMTVSDWYDQ

Parental  HRKYGALPDQGIAKTTPAVKEKGDDGEIRHRAREWD
          .RKYGALPDQGIAKTTPA...K...........E.D
Retrocopy QRKYGALPDQGIAKTTPAEFKKAPQKQEDQEPKEED

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2206 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 48 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000007797	1 retrocopy	retro_btau_215,
Choloepus hoffmanni	ENSCHOG00000013654	3 retrocopies	retro_chof_1523, retro_chof_2206 , retro_chof_438,
Callithrix jacchus	ENSCJAG00000012525	6 retrocopies	retro_cjac_111, retro_cjac_1225, retro_cjac_2278, retro_cjac_2968, retro_cjac_3417, retro_cjac_47,
Cavia porcellus	ENSCPOG00000010797	1 retrocopy	retro_cpor_44,
Dasypus novemcinctus	ENSDNOG00000014731	5 retrocopies	retro_dnov_1160, retro_dnov_2029, retro_dnov_2340, retro_dnov_2380, retro_dnov_678,
Echinops telfairi	ENSETEG00000003397	1 retrocopy	retro_etel_1637,
Felis catus	ENSFCAG00000029688	1 retrocopy	retro_fcat_23,
Homo sapiens	ENSG00000089289	5 retrocopies	retro_hsap_1317, retro_hsap_1848, retro_hsap_2766, retro_hsap_2919, retro_hsap_3059,
Gorilla gorilla	ENSGGOG00000027795	2 retrocopies	retro_ggor_112, retro_ggor_2020,
Myotis lucifugus	ENSMLUG00000004179	1 retrocopy	retro_mluc_316,
Macaca mulatta	ENSMMUG00000013929	2 retrocopies	retro_mmul_1545, retro_mmul_31,
Mus musculus	ENSMUSG00000031221	1 retrocopy	retro_mmus_169,
Nomascus leucogenys	ENSNLEG00000000747	5 retrocopies	retro_nleu_1399, retro_nleu_1653, retro_nleu_2334, retro_nleu_671, retro_nleu_828,
Otolemur garnettii	ENSOGAG00000011797	1 retrocopy	retro_ogar_110,
Pongo abelii	ENSPPYG00000020435	4 retrocopies	retro_pabe_1099, retro_pabe_1451, retro_pabe_2245, retro_pabe_2533,
Pan troglodytes	ENSPTRG00000021990	5 retrocopies	retro_ptro_1233, retro_ptro_1873, retro_ptro_1973, retro_ptro_1982, retro_ptro_901,
Pteropus vampyrus	ENSPVAG00000005483	1 retrocopy	retro_pvam_1462,
Rattus norvegicus	ENSRNOG00000026267	1 retrocopy	retro_rnor_311,
Tarsius syrichta	ENSTSYG00000006214	2 retrocopies	retro_tsyr_1537, retro_tsyr_2131,