RetrogeneDB ID: retro_cfam_506

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 12:6463160..6463548(-)
• Located in intron of: ENSCAFG00000001477

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000031458
• Aliases: None
• Description: Cytochrome c oxidase subunit 6A, mitochondrial [Source:UniProtKB/TrEMBL;Acc:J9P8X9]

Sequence

>retro_cfam_506
CCTAAAGAAATAATCCTACCCTCACAGAGTTTAAAAATCAAATAACTAAGGTCCAGGTCAAAAATGGTAGTGACAGCTGG
GTCTTGGGTTTCTAGGCTGCTAGGTAGGTCTGGGGCATAGCTGGGGCAGTCCATGTTGAGTGGTGCTCACAGCAATGAGG
AGGGCTCAGCTCAGATGTGGAAGGCACTCCCCTACTTCATAGAGCTCACCAGTGAGGGAGTGAGTATGCTGACCGTCTTC
CTGAAGTCGCACCTGGAGAGCATATAGAGCCTTGAGTTCGCCGCCTACGACTATCTCTTCATCAGGTCCAAGCCCTTTCT
CGGGGGAGATGGTTCACACTCCATTCCATTAACTCTCATGTGAATCCTTTCCAACTGGCTATGAAAAT

Alignment

ORF - retro_cfam_506 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.52 %
• Parental protein coverage: 54.08 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  PAHFPLPLPALRL----SRSIMASAAAVFRLSGLLGRSGAPLGRSMSSGAHG-EEGSARMWKALTYFVAL
          P....LP...L......SRS.M...A.....S.LLGRSGA.LG.SM.SGAH..EEGSA.MWKAL.YF..L
Retrocopy PKEIILPSQSLKIK*LRSRSKMVVTAGSW-VSRLLGRSGA*LGQSMLSGAHSNEEGSAQMWKALPYFIEL

Parental  PGVGVSMLNVFLKSH-HGEHERP-EFIAYPHLRIRSKPFPWGDGNHTL-FHNSHVNP-LPTGYED
          ...GVSML.VFLKSH..GEH..P.EF.AY..L.IRSKPF..GDG.H.....NSHVNP..PTGYE.
Retrocopy TSEGVSMLTVFLKSH<PGEHIEP>EFAAYDYLFIRSKPFLGGDGSHSI<SINSHVNP<FPTGYEN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	129.52 RPM
SRP017611_brain	0.00 RPM	114.48 RPM
SRP017611_kidney	0.00 RPM	381.56 RPM
SRP017611_liver	0.00 RPM	76.65 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_506 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_506 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_506 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 80 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000012788	1 retrocopy	retro_btau_229,
Canis familiaris	ENSCAFG00000031458	1 retrocopy	retro_cfam_506 ,
Choloepus hoffmanni	ENSCHOG00000009222	2 retrocopies	retro_chof_2085, retro_chof_2579,
Callithrix jacchus	ENSCJAG00000001174	6 retrocopies	retro_cjac_102, retro_cjac_1332, retro_cjac_205, retro_cjac_2541, retro_cjac_3173, retro_cjac_912,
Cavia porcellus	ENSCPOG00000006426	1 retrocopy	retro_cpor_1265,
Equus caballus	ENSECAG00000012512	2 retrocopies	retro_ecab_578, retro_ecab_845,
Echinops telfairi	ENSETEG00000016826	1 retrocopy	retro_etel_1482,
Felis catus	ENSFCAG00000031188	9 retrocopies	retro_fcat_1049, retro_fcat_1399, retro_fcat_1505, retro_fcat_1518, retro_fcat_1653, retro_fcat_1891, retro_fcat_318, retro_fcat_753, retro_fcat_886,
Homo sapiens	ENSG00000111775	1 retrocopy	retro_hsap_25,
Gorilla gorilla	ENSGGOG00000014101	2 retrocopies	retro_ggor_176, retro_ggor_2527,
Myotis lucifugus	ENSMLUG00000010330	4 retrocopies	retro_mluc_1127, retro_mluc_1405, retro_mluc_1879, retro_mluc_465,
Macaca mulatta	ENSMMUG00000016000	2 retrocopies	retro_mmul_127, retro_mmul_2535,
Nomascus leucogenys	ENSNLEG00000015644	4 retrocopies	retro_nleu_1116, retro_nleu_412, retro_nleu_484, retro_nleu_985,
Oryctolagus cuniculus	ENSOCUG00000009873	6 retrocopies	retro_ocun_1320, retro_ocun_1668, retro_ocun_1700, retro_ocun_174, retro_ocun_1898, retro_ocun_1928,
Otolemur garnettii	ENSOGAG00000003561	18 retrocopies	retro_ogar_1068, retro_ogar_111, retro_ogar_1150, retro_ogar_1466, retro_ogar_188, retro_ogar_1904, retro_ogar_2063, retro_ogar_2312, retro_ogar_2933, retro_ogar_3021, retro_ogar_3106, retro_ogar_3190, retro_ogar_3227, retro_ogar_3240, retro_ogar_346, retro_ogar_852, retro_ogar_871, retro_ogar_872,
Pongo abelii	ENSPPYG00000005028	4 retrocopies	retro_pabe_2905, retro_pabe_3087, retro_pabe_3206, retro_pabe_713,
Pan troglodytes	ENSPTRG00000005532	3 retrocopies	retro_ptro_311, retro_ptro_54, retro_ptro_556,
Pteropus vampyrus	ENSPVAG00000002226	3 retrocopies	retro_pvam_1060, retro_pvam_790, retro_pvam_910,
Rattus norvegicus	ENSRNOG00000001170	2 retrocopies	retro_rnor_2581, retro_rnor_2680,
Tupaia belangeri	ENSTBEG00000008018	4 retrocopies	retro_tbel_2490, retro_tbel_3010, retro_tbel_3167, retro_tbel_395,
Tarsius syrichta	ENSTSYG00000011541	1 retrocopy	retro_tsyr_1025,
Tursiops truncatus	ENSTTRG00000000142	2 retrocopies	retro_ttru_1873, retro_ttru_889,
Vicugna pacos	ENSVPAG00000010359	1 retrocopy	retro_vpac_218,