RetrogeneDB ID: retro_cfam_2135

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: X:12315495..12315882(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: BTF3L4
• Ensembl ID: ENSCAFG00000003782
• Aliases: None
• Description: basic transcription factor 3-like 4 [Source:HGNC Symbol;Acc:30547]

Sequence

>retro_cfam_2135
AACCAGGAAAAACTCCCCAAACTGCAAGCACAAGTGCACATTGGTGGGGAAGGAACTGCTCACCGAAAGAAGAAGGTGGT
TCATAGGACAGCTACAGCAGATGATAAAAAAAGCTTCAGTTCTCCTGAAAGAAGTTGGGGGTAGACAACACCTCTGGTAC
TGGAGACGTGAACATGTTCACAAACTGGGGAACAGTGACCCACTGTAACAACCCTACAGTTCAGGCATAGCTGGCAGCGA
ACACTGTCACCATTCCAGGCTGTGCTGAGACAGCAGCCCACAGAAATGCTCCCCAGGATCCTACACCAGCTGGGTGCAGA
CGCTCTGGCTAGTTTAAGAAGACTGGCTGAAGCTCTGCCCACACACCCTGTGGATGGGAAAGCACCA

Alignment

ORF - retro_cfam_2135 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.91 %
• Parental protein coverage: 81.65 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  NQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSS-LKK-LAVNNIAGIEEVNMIKDDGTVIHF
          NQEKL.KLQAQV.IGG.GTA.RKKKVVHRTATADDKK..SS.LK..L.V.N..G...VNM....GTV.H.
Retrocopy NQEKLPKLQAQVHIGGEGTAHRKKKVVHRTATADDKKSFSS>LKE>LGVDNTSGTGDVNMFTNWGTVTHC

Parental  NNPKVQASLSANTFAITGHAEA-KPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAP
          NNP.VQA.L.ANT..I.G.AE...P.TEMLP.IL.QLGAD.L.SLR.LAE..P....D.KAP
Retrocopy NNPTVQA*LAANTVTIPGCAET>QP-TEMLPRILHQLGADALASLRRLAEALPTHPVDGKAP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	23.35 RPM
SRP017611_brain	0.00 RPM	25.64 RPM
SRP017611_kidney	0.00 RPM	51.77 RPM
SRP017611_liver	0.00 RPM	15.30 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_2135 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_2135 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_2135 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 70 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000011025	1 retrocopy	retro_btau_1030,
Canis familiaris	ENSCAFG00000003782	2 retrocopies	retro_cfam_2135 , retro_cfam_938,
Canis familiaris	ENSCAFG00000008212	3 retrocopies	retro_cfam_1660, retro_cfam_1741, retro_cfam_531,
Callithrix jacchus	ENSCJAG00000021582	4 retrocopies	retro_cjac_2000, retro_cjac_2929, retro_cjac_4160, retro_cjac_451,
Cavia porcellus	ENSCPOG00000004006	1 retrocopy	retro_cpor_908,
Ciona savignyi	ENSCSAVG00000009653	1 retrocopy	retro_csav_25,
Dasypus novemcinctus	ENSDNOG00000003181	4 retrocopies	retro_dnov_1690, retro_dnov_1928, retro_dnov_2672, retro_dnov_921,
Echinops telfairi	ENSETEG00000011923	11 retrocopies	retro_etel_1017, retro_etel_1167, retro_etel_1207, retro_etel_1409, retro_etel_1990, retro_etel_2113, retro_etel_2203, retro_etel_291, retro_etel_663, retro_etel_804, retro_etel_953,
Loxodonta africana	ENSLAFG00000016124	3 retrocopies	retro_lafr_206, retro_lafr_769, retro_lafr_947,
Macropus eugenii	ENSMEUG00000006135	10 retrocopies	retro_meug_1114, retro_meug_1164, retro_meug_1333, retro_meug_1395, retro_meug_1512, retro_meug_1663, retro_meug_2008, retro_meug_298, retro_meug_903, retro_meug_966,
Myotis lucifugus	ENSMLUG00000016884	1 retrocopy	retro_mluc_912,
Macaca mulatta	ENSMMUG00000003636	1 retrocopy	retro_mmul_59,
Monodelphis domestica	ENSMODG00000000770	2 retrocopies	retro_mdom_33, retro_mdom_992,
Mustela putorius furo	ENSMPUG00000006966	2 retrocopies	retro_mputfur_1444, retro_mputfur_924,
Mus musculus	ENSMUSG00000028568	2 retrocopies	retro_mmus_1134, retro_mmus_2743,
Oryctolagus cuniculus	ENSOCUG00000001517	3 retrocopies	retro_ocun_1001, retro_ocun_1412, retro_ocun_1912,
Otolemur garnettii	ENSOGAG00000030256	2 retrocopies	retro_ogar_2759, retro_ogar_570,
Ochotona princeps	ENSOPRG00000013335	2 retrocopies	retro_opri_719, retro_opri_974,
Procavia capensis	ENSPCAG00000006428	3 retrocopies	retro_pcap_129, retro_pcap_307, retro_pcap_373,
Pongo abelii	ENSPPYG00000001353	2 retrocopies	retro_pabe_1850, retro_pabe_3010,
Rattus norvegicus	ENSRNOG00000008512	8 retrocopies	retro_rnor_1113, retro_rnor_1666, retro_rnor_1870, retro_rnor_1871, retro_rnor_1872, retro_rnor_537, retro_rnor_760, retro_rnor_998,
Sorex araneus	ENSSARG00000003173	2 retrocopies	retro_sara_680, retro_sara_690,