RetrogeneDB ID: retro_cfam_1259

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 28:6121434..6121745(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: COX4I1
• Ensembl ID: ENSCAFG00000019921
• Aliases: None
• Description: cytochrome c oxidase subunit IV isoform 1 [Source:HGNC Symbol;Acc:2265]

Sequence

>retro_cfam_1259
ATGTTGGTGACCAGGGGAGTATTTGGCCTAACTGGCAAGCGAGCCATTCCACCTCCGGGTGTGTGTGAGCACCTGGAAGT
GTCGTGAGGAGTGAAACCCGTGCTCTCCGAGTTATGTCGACCAGCGCGGACTATCCCTCGCCTGATGCGGCCACGTCAGG
ATCCTCTCTGCCAGCCAGAGGGCCTTGAAATAAAAGGAGGAGGCCCCTTTGAGCAGCCTCTCTTTTTGATGAAAATGTCG
CATCGTGCCGCATTAAACTCTGTGAGAGCTTTGCTGACGTGAACAGGAGCACACACAAGCACAAGACGGTG

Alignment

ORF - retro_cfam_1259 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.14 %
• Parental protein coverage: 60.95 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 5

Retrocopy - Parental Gene Alignment:

Parental  MLATR-VFSLIGKRAF-STSVCVRAHGSVVKSEDFAL-PSYVDRR-DYPLPDVA-HVKNLSASQKALKEK
          ML.TR.VF.L.GKRA..STS.CV.A.GSVV.SE..AL.PSYVD.R.DYP.PD.A.HV..LSASQ.ALK.K
Retrocopy MLVTRGVFGLTGKRAI<STSGCV*APGSVVRSETRAL<PSYVDQR>DYPSPDAA<HVRILSASQRALK*K

Parental  EKASWSSLS-IDEKVELYRIKFNESFAEMNRSTNEWKTV
          E.A..SSLS..DE.V...RIK..ESFA..NRST...KTV
Retrocopy EEAPLSSLS>FDENVASCRIKLCESFADVNRSTHKHKTV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.04 RPM	125.49 RPM
SRP017611_brain	0.00 RPM	137.98 RPM
SRP017611_kidney	0.07 RPM	463.25 RPM
SRP017611_liver	0.00 RPM	88.61 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1259 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1259 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1259 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 42 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000005479	1 retrocopy	retro_acar_90,
Ailuropoda melanoleuca	ENSAMEG00000018274	1 retrocopy	retro_amel_470,
Bos taurus	ENSBTAG00000016079	2 retrocopies	retro_btau_1406, retro_btau_483,
Canis familiaris	ENSCAFG00000019921	2 retrocopies	retro_cfam_1259 , retro_cfam_1906,
Callithrix jacchus	ENSCJAG00000017319	4 retrocopies	retro_cjac_2267, retro_cjac_3264, retro_cjac_3300, retro_cjac_802,
Dasypus novemcinctus	ENSDNOG00000017207	3 retrocopies	retro_dnov_2207, retro_dnov_2396, retro_dnov_737,
Equus caballus	ENSECAG00000011722	1 retrocopy	retro_ecab_418,
Felis catus	ENSFCAG00000007612	2 retrocopies	retro_fcat_1484, retro_fcat_853,
Homo sapiens	ENSG00000131143	1 retrocopy	retro_hsap_1428,
Gorilla gorilla	ENSGGOG00000010047	1 retrocopy	retro_ggor_1101,
Loxodonta africana	ENSLAFG00000014002	1 retrocopy	retro_lafr_528,
Macaca mulatta	ENSMMUG00000006763	4 retrocopies	retro_mmul_1129, retro_mmul_1285, retro_mmul_1724, retro_mmul_2260,
Mus musculus	ENSMUSG00000031818	2 retrocopies	retro_mmus_1305, retro_mmus_2958,
Nomascus leucogenys	ENSNLEG00000011409	1 retrocopy	retro_nleu_1843,
Oryctolagus cuniculus	ENSOCUG00000001735	5 retrocopies	retro_ocun_1238, retro_ocun_1333, retro_ocun_317, retro_ocun_469, retro_ocun_889,
Ochotona princeps	ENSOPRG00000002129	4 retrocopies	retro_opri_1205, retro_opri_267, retro_opri_821, retro_opri_857,
Pongo abelii	ENSPPYG00000007619	3 retrocopies	retro_pabe_1183, retro_pabe_1184, retro_pabe_996,
Pan troglodytes	ENSPTRG00000008434	1 retrocopy	retro_ptro_977,
Rattus norvegicus	ENSRNOG00000017817	1 retrocopy	retro_rnor_1157,
Tarsius syrichta	ENSTSYG00000009682	2 retrocopies	retro_tsyr_2073, retro_tsyr_591,