RetrogeneDB ID: retro_nleu_2379

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397350.1:2659804..2660441(+)
• Located in intron of: ENSNLEG00000010690

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C1QBP
• Ensembl ID: ENSNLEG00000009081
• Aliases: None
• Description: complement component 1, q subcomponent binding protein [Source:HGNC Symbol;Acc:1243]

Sequence

>retro_nleu_2379
GGGTCTGCGTGGCAGCCTGACCTGCTGTGGCCTCCTAGGCCCTGTGCCTGTGGCTACAGTGGCTGCGTGCTGTGCACCAA
AGGAGACAGAGCTTCTGTTGAATTCCTGAGTGATGAAATTAAGGAGGAAAGGGAAATCGAGAAGCATAAGAGGCATTCCC
TCCCTAAGAGGTCTGGAAGTTGGGAGCTAGAATTTAAATGGAACAGAAGCTAAATTAGCATGGCAAGTTGCCAGGGGAAA
GATCACTGTCACTTTCAACATTATCAACAGCATCCCACCCACATCTGATGGTGAGGAGGAGCCCTCACAAGGGCTGTAGG
TTGAAGAACAGGATTCTGAATTGACATCAACTCCCAGTTTCATAGTTGAAGTTATGAAGAATGATAGCAAGAAGGTCCTG
GTGCTGACTGTCACTATCAGAGGATGAGTTTGGACAAGAGCAGGTGGAGAGTAACATTTTCTCCATCAGGGAAGTTAGCT
TTCAGTCCAATGGCAAGTCTGGACGGAAGGGCACTAGTACACACTCAACGCAGAGTCCCCGGACTAGGCCTTGTATTATT
TCCTTGAGGACAAAGGGGTGGACAACGCTTTTGTGGAAGGGTTGGTGGAGCTCAGCACAGTTCCGGAGCACCAGGAG

Alignment

ORF - retro_nleu_2379 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.12 %
• Parental protein coverage: 65.85 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  GSERRPGLLRPRGPCACGCGCGSLHTEGDRAFVDFLSDEIKEERKIQKHK--TLPKMSGGWELE-LNGTE
          GS...P.LL.P..PCACG.....L.T.GDRA.V.FLSDEIKEER.I.KHK...LPK.SG.WELE.LNGTE
Retrocopy GSAWQPDLLWPPRPCACGYSGCVLCTKGDRASVEFLSDEIKEEREIEKHKRHSLPKRSGSWELE>LNGTE

Parental  AKLVRKVAGEKITVTFNINNSIPPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDGKKALVL-DCH
          AKL...VA..KITVTFNI.NSIPPT.DGEEEPSQG..VEEQ..ELTSTP.F.VEV.KND.KK.LVL.DCH
Retrocopy AKLAWQVARGKITVTFNIINSIPPTSDGEEEPSQGL*VEEQDSELTSTPSFIVEVMKNDSKKVLVL<DCH

Parental  Y-PEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTN-YTLNTDSLDWALYDHLMDFLADRGVDNTFADE
          Y..EDE.GQE...ES.IFSIREVSFQS.G.S..K.T..YTLN..S.D.ALY..L.D.....GVDN.F...
Retrocopy Y<SEDEFGQE-QVESNIFSIREVSFQSNGKSGRKGTS<YTLNAESPD*ALYYFLED----KGVDNAFVEG

Parental  LVELSTALEHQE
          LVELST..EHQE
Retrocopy LVELSTVPEHQE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_2379 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 55 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000006043	2 retrocopies	retro_amel_1734, retro_amel_356,
Callithrix jacchus	ENSCJAG00000011352	6 retrocopies	retro_cjac_2041, retro_cjac_2408, retro_cjac_4033, retro_cjac_604, retro_cjac_680, retro_cjac_946,
Dasypus novemcinctus	ENSDNOG00000008887	3 retrocopies	retro_dnov_1151, retro_dnov_1946, retro_dnov_702,
Felis catus	ENSFCAG00000026474	3 retrocopies	retro_fcat_1135, retro_fcat_1763, retro_fcat_892,
Homo sapiens	ENSG00000108561	2 retrocopies	retro_hsap_1475, retro_hsap_2516,
Gorilla gorilla	ENSGGOG00000002745	5 retrocopies	retro_ggor_1133, retro_ggor_1569, retro_ggor_3007, retro_ggor_3008, retro_ggor_717,
Macropus eugenii	ENSMEUG00000014882	13 retrocopies	retro_meug_1068, retro_meug_1347, retro_meug_1363, retro_meug_1446, retro_meug_1901, retro_meug_1940, retro_meug_1970, retro_meug_2069, retro_meug_2128, retro_meug_434, retro_meug_580, retro_meug_988, retro_meug_989,
Macaca mulatta	ENSMMUG00000006592	1 retrocopy	retro_mmul_1554,
Nomascus leucogenys	ENSNLEG00000009081	2 retrocopies	retro_nleu_2379 , retro_nleu_3038,
Otolemur garnettii	ENSOGAG00000001610	5 retrocopies	retro_ogar_1376, retro_ogar_2502, retro_ogar_2518, retro_ogar_2879, retro_ogar_768,
Ochotona princeps	ENSOPRG00000013150	1 retrocopy	retro_opri_408,
Pongo abelii	ENSPPYG00000007870	6 retrocopies	retro_pabe_1222, retro_pabe_1385, retro_pabe_1413, retro_pabe_1866, retro_pabe_1868, retro_pabe_670,
Pan troglodytes	ENSPTRG00000008631	3 retrocopies	retro_ptro_1140, retro_ptro_1461, retro_ptro_998,
Pteropus vampyrus	ENSPVAG00000002466	1 retrocopy	retro_pvam_384,
Sarcophilus harrisii	ENSSHAG00000002441	2 retrocopies	retro_shar_620, retro_shar_813,