RetrogeneDB ID: retro_mmus_747

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 11:100243272..100243626(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000082456
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Tceb2
• Ensembl ID: ENSMUSG00000055839
• Aliases: Tceb2, 0610040H15Rik
• Description: transcription elongation factor B (SIII), polypeptide 2 [Source:MGI Symbol;Acc:MGI:1914923]

Sequence

>retro_mmus_747
ATGGACGTGTTTCTCATGATCCGGCGCCACAAGACCACCATCTTTACGGACGCCAAGGAGTCGAGCACCGTGTTCGAACT
GAAGCGCATCATCTAGGGCATCCTCAAGCGGCCGCCAGAGGAGCAGCGGCTTTACAAGGATGACCAGCTCCTTGAGGATG
GCAAAACTCTGGGCGAGTGTGGCTTCACTAGCCAGACACCACGGCCACAGGCCCCAGCCACGGTGGGCCTGGCCTTCTGA
GCAGATGGCACCTTCGAAGCTCTCTGCATCAAGCCCTTCTCCAGCCCTCCAAAGCTTCCAGATGTGATGAAGCCACAGGA
TTCTGGAGGCAGTGCCAATGAACAAGCTGTGCAG

Alignment

ORF - retro_mmus_747 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.37 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQ
          MDVFLMIRRHKTTIFTDAKESSTVFELKRI..GILKRPPEEQRLYKDDQLL.DGKTLGECGFTSQT.RPQ
Retrocopy MDVFLMIRRHKTTIFTDAKESSTVFELKRII*GILKRPPEEQRLYKDDQLLEDGKTLGECGFTSQTPRPQ

Parental  APATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDSGGSANEQAVQ
          APATVGLAF.AD.TFEAL.I.PFSSPP.LPDVMKPQDSGGSANEQAVQ
Retrocopy APATVGLAF*ADGTFEALCIKPFSSPPKLPDVMKPQDSGGSANEQAVQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	34.18 RPM
SRP007412_cerebellum	0.00 RPM	20.36 RPM
SRP007412_heart	0.09 RPM	27.80 RPM
SRP007412_kidney	0.06 RPM	19.50 RPM
SRP007412_liver	0.05 RPM	14.88 RPM
SRP007412_testis	0.14 RPM	71.72 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_747 was not detected

EST

No EST(s) were mapped for retro_mmus_747 retrocopy.

TSS

TSS No.	TSS Name	TSS expression level (Expr) in TPM range:
		no expression	0 < Expr ≤ 1	1 < Expr ≤ 5	5 < Expr ≤ 10	Expr > 10
TSS #1	TSS_7834	148 libraries	317 libraries	549 libraries	51 libraries	7 libraries

The graphical summary, for retro_mmus_747 TSS expression levels > 0 TPM .
TSS expression levels were studied across 1072 TSS-CAGE libraries, based on FANTOM5 data.
The expression values were visualized using beanplot. If you have any doubts, how to read it, read more in Kampstra P (2008)

Lab

retro_mmus_747 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_747 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 15 parental genes, and 44 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019543	3 retrocopies	retro_btau_142, retro_btau_17, retro_btau_29,
Callithrix jacchus	ENSCJAG00000015347	10 retrocopies	retro_cjac_1593, retro_cjac_1606, retro_cjac_2051, retro_cjac_2613, retro_cjac_2987, retro_cjac_3030, retro_cjac_342, retro_cjac_3819, retro_cjac_639, retro_cjac_959,
Cavia porcellus	ENSCPOG00000021024	1 retrocopy	retro_cpor_1416,
Felis catus	ENSFCAG00000004711	2 retrocopies	retro_fcat_112, retro_fcat_40,
Homo sapiens	ENSG00000103363	2 retrocopies	retro_hsap_1246, retro_hsap_940,
Gorilla gorilla	ENSGGOG00000015306	1 retrocopy	retro_ggor_976,
Monodelphis domestica	ENSMODG00000016536	4 retrocopies	retro_mdom_1149, retro_mdom_1617, retro_mdom_1964, retro_mdom_23,
Mustela putorius furo	ENSMPUG00000015265	1 retrocopy	retro_mputfur_469,
Mus musculus	ENSMUSG00000055839	7 retrocopies	retro_mmus_1212, retro_mmus_1489, retro_mmus_1664, retro_mmus_2930, retro_mmus_511, retro_mmus_747 , retro_mmus_99,
Nomascus leucogenys	ENSNLEG00000009471	2 retrocopies	retro_nleu_295, retro_nleu_89,
Oryctolagus cuniculus	ENSOCUG00000010116	2 retrocopies	retro_ocun_202, retro_ocun_930,
Pongo abelii	ENSPPYG00000007013	1 retrocopy	retro_pabe_74,
Pan troglodytes	ENSPTRG00000007663	1 retrocopy	retro_ptro_857,
Rattus norvegicus	ENSRNOG00000004814	6 retrocopies	retro_rnor_1226, retro_rnor_1275, retro_rnor_185, retro_rnor_1948, retro_rnor_35, retro_rnor_352,
Sus scrofa	ENSSSCG00000008061	1 retrocopy	retro_sscr_858,