RetrogeneDB ID: retro_ggor_2415

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:37085674..37086040(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NUDT5
• Ensembl ID: ENSGGOG00000006325
• Aliases: None
• Description: None

Sequence

>retro_ggor_2415
CTCATAGATGATGGTGAAACCCCAGGAGCAGCTGCTCTTTGGGAGCTTGAGGAAGAAACTGGCCACAAAGGGGACGTTGC
CGAATGTTCTCCAGTGGTCTGTATGGACCCAGGTTTGTCAAACTATACCACACACATCGTGACAGTAATCATTAACGGAG
ATGACGCAGAAAATGTAAGGCCCAAGCCAAAGCCAGGGGATGGAGAATTTGTGGAAGTCATTTCGTTACCCAAGAATGAC
CTGCTGCAGGGACTCGATGCTCTCGTAGCTGAAAAACATCTTACAGTGGATGCCAGAGTCTATTCCCATGCTCTAGCACT
GAAACATGCAAATGCGAAGCCATTTGAAGTGCCCGTCCTGAAATTT

Alignment

ORF - retro_ggor_2415 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.34 %
• Parental protein coverage: 54.95 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEF
          LIDDGETP.AAAL.ELEEETG.KGD.AECSP.VCMDPGLSN.T.HIVTV.INGDDAEN.RPKPKPGDGEF
Retrocopy LIDDGETPGAAALWELEEETGHKGDVAECSPVVCMDPGLSNYTTHIVTVIINGDDAENVRPKPKPGDGEF

Parental  VEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF
          VEVISLPKNDLLQ.LDALVAE.HLTVDARVYS.ALALKHANAKPFEVP.LKF
Retrocopy VEVISLPKNDLLQGLDALVAEKHLTVDARVYSHALALKHANAKPFEVPVLKF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.19 RPM	6.95 RPM
SRP007412_cerebellum	0.08 RPM	8.04 RPM
SRP007412_heart	0.00 RPM	1.94 RPM
SRP007412_kidney	0.04 RPM	14.11 RPM
SRP007412_liver	0.11 RPM	13.72 RPM
SRP007412_testis	0.31 RPM	11.71 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2415 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2415 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3580
Pan troglodytes	retro_ptro_2427
Pongo abelii	retro_pabe_2949
Macaca mulatta	retro_mmul_1828

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019509	2 retrocopies	retro_btau_1326, retro_btau_1438,
Canis familiaris	ENSCAFG00000004794	2 retrocopies	retro_cfam_435, retro_cfam_612,
Equus caballus	ENSECAG00000023658	1 retrocopy	retro_ecab_647,
Echinops telfairi	ENSETEG00000006403	1 retrocopy	retro_etel_946,
Felis catus	ENSFCAG00000025093	1 retrocopy	retro_fcat_350,
Homo sapiens	ENSG00000165609	1 retrocopy	retro_hsap_3580,
Gorilla gorilla	ENSGGOG00000006325	1 retrocopy	retro_ggor_2415 ,
Loxodonta africana	ENSLAFG00000012052	1 retrocopy	retro_lafr_226,
Myotis lucifugus	ENSMLUG00000010453	2 retrocopies	retro_mluc_1263, retro_mluc_2073,
Macaca mulatta	ENSMMUG00000017141	1 retrocopy	retro_mmul_1828,
Nomascus leucogenys	ENSNLEG00000012298	1 retrocopy	retro_nleu_2838,
Oryctolagus cuniculus	ENSOCUG00000009308	1 retrocopy	retro_ocun_862,
Otolemur garnettii	ENSOGAG00000005816	2 retrocopies	retro_ogar_2071, retro_ogar_2988,
Pongo abelii	ENSPPYG00000002091	2 retrocopies	retro_pabe_2949, retro_pabe_3040,
Pan troglodytes	ENSPTRG00000002294	1 retrocopy	retro_ptro_2427,
Rattus norvegicus	ENSRNOG00000017741	1 retrocopy	retro_rnor_1672,
Sus scrofa	ENSSSCG00000011113	1 retrocopy	retro_sscr_143,
Tursiops truncatus	ENSTTRG00000007394	2 retrocopies	retro_ttru_209, retro_ttru_495,