RetrogeneDB ID: retro_btau_1844

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: X:101428042..101428600(-)
• Located in intron of: ENSBTAG00000035705

Retrocopy information

• Ensembl ID: ENSBTAG00000046004
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: NDUFB8
• Ensembl ID: ENSBTAG00000000091
• Aliases: None
• Description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q02372]

Sequence

>retro_btau_1844
ATGGCGGCGGCCAGGGTGGGGGTCCTGGGAGTCCGATGGCTGCAAAAGGCAGCCCAAAACGTGGTGCCACTGGGTGCACG
GACAGCCTCCCACATTACCAAGGACATGCTCCCGGGACCCTATCCCAAGACCCCAGAAGAACGGGCTGCCGCCGCCAAGA
AGTATAATATGCGGGTGGAAGACTACGAGCCGTACCCAGATGATGGCATGGGGTATGGTGACTATCCGAAACTGCCTGAC
CGCTCACAGCAGGAGAGGGATCCATGGTATGACTGGGACCACCCAGACCTGCAGTTGAACTGGGGTGAACTGATGCACTG
GGACCTGGACATGTATATCAGGAACCGTGTGGACATGTCCCCGACTCCTGTTAACTGGAACCTCATGTGTAAGCACCTCT
TCGGCTTCGTCGCCTTCATGCTGTTCATGTTTTGGGTAGGGGAGACTTACCCCGCCTACCAGCCTGTGGGGCCAAAGCAG
TATCCTTACAATAATCTGTACCTGGAACGAGGCGGCGATCCCAACAAAGAACCTGAGCCAGTGGTTCACTATGAGATC

Alignment

ORF - retro_btau_1844 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.77 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAAARAGVLGVRWLQKAARNVVPLGARTASHITKDMLPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDGT
          MAAAR.GVLGVRWLQKAA.NVVPLGARTASHITKDMLPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDG.
Retrocopy MAAARVGVLGVRWLQKAAQNVVPLGARTASHITKDMLPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDGM

Parental  GYGDYPKLPDRSQQERDPWYDWDHPDLRLNWGEPMHWDLDMYIRNRVDTSPTPVNWNLMCKHLFGFVAFM
          GYGDYPKLPDRSQQERDPWYDWDHPDL.LNWGE.MHWDLDMYIRNRVD.SPTPVNWNLMCKHLFGFVAFM
Retrocopy GYGDYPKLPDRSQQERDPWYDWDHPDLQLNWGELMHWDLDMYIRNRVDMSPTPVNWNLMCKHLFGFVAFM

Parental  LFMFWVGETYPAYQPVGPKQYPYNNLYLERGGDPNKEPEPVVHYEI
          LFMFWVGETYPAYQPVGPKQYPYNNLYLERGGDPNKEPEPVVHYEI
Retrocopy LFMFWVGETYPAYQPVGPKQYPYNNLYLERGGDPNKEPEPVVHYEI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.43 RPM	24.08 RPM
ERP005899_muscle	0.48 RPM	85.36 RPM
SRP017611_brain	0.23 RPM	42.71 RPM
SRP017611_kidney	0.06 RPM	50.26 RPM
SRP017611_liver	0.00 RPM	28.16 RPM
SRP030211_testis	0.92 RPM	68.08 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1844 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1844 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1844 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000006651	3 retrocopies	retro_amel_1460, retro_amel_1467, retro_amel_931,
Bos taurus	ENSBTAG00000000091	1 retrocopy	retro_btau_1844 ,
Canis familiaris	ENSCAFG00000009698	2 retrocopies	retro_cfam_1405, retro_cfam_1947,
Callithrix jacchus	ENSCJAG00000037906	1 retrocopy	retro_cjac_870,
Dasypus novemcinctus	ENSDNOG00000003661	1 retrocopy	retro_dnov_65,
Felis catus	ENSFCAG00000006453	2 retrocopies	retro_fcat_501, retro_fcat_856,
Homo sapiens	ENSG00000166136	3 retrocopies	retro_hsap_1363, retro_hsap_1772, retro_hsap_770,
Gorilla gorilla	ENSGGOG00000027239	3 retrocopies	retro_ggor_1062, retro_ggor_2240, retro_ggor_639,
Microcebus murinus	ENSMICG00000001341	1 retrocopy	retro_mmur_859,
Myotis lucifugus	ENSMLUG00000015094	1 retrocopy	retro_mluc_1830,
Macaca mulatta	ENSMMUG00000006636	5 retrocopies	retro_mmul_1098, retro_mmul_1232, retro_mmul_1620, retro_mmul_415, retro_mmul_753,
Monodelphis domestica	ENSMODG00000019356	1 retrocopy	retro_mdom_1543,
Mustela putorius furo	ENSMPUG00000016959	1 retrocopy	retro_mputfur_1259,
Mus musculus	ENSMUSG00000025204	2 retrocopies	retro_mmus_1995, retro_mmus_2909,
Nomascus leucogenys	ENSNLEG00000014774	3 retrocopies	retro_nleu_1068, retro_nleu_2810, retro_nleu_398,
Otolemur garnettii	ENSOGAG00000030711	3 retrocopies	retro_ogar_1237, retro_ogar_152, retro_ogar_2593,
Pongo abelii	ENSPPYG00000002570	3 retrocopies	retro_pabe_1131, retro_pabe_1541, retro_pabe_756,
Pan troglodytes	ENSPTRG00000002851	3 retrocopies	retro_ptro_1186, retro_ptro_539, retro_ptro_936,
Sus scrofa	ENSSSCG00000006166	2 retrocopies	retro_sscr_1092, retro_sscr_444,
Tupaia belangeri	ENSTBEG00000000209	8 retrocopies	retro_tbel_1872, retro_tbel_2950, retro_tbel_3122, retro_tbel_322, retro_tbel_3696, retro_tbel_4042, retro_tbel_4718, retro_tbel_540,