RetrogeneDB ID: retro_pabe_1814

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 20:24263112..24263604(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSPPYG00000010804
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: FTL
• Ensembl ID: ENSPPYG00000010223
• Aliases: None
• Description: Ferritin light chain [Source:UniProtKB/Swiss-Prot;Acc:Q5R538]

Sequence

>retro_pabe_1814
ATGAGCTCCCAGATTCGTCAGAATTATTCCNACCGACGTGGAGGCAGCCGTCAACAGCCTGGGCAATTTGTACCTCCAGG
CCTCCTACACCTACCTCTCTCTGGGCTTCTATTTCGACCGCAATGATGTGGCTCTGGAAGGCGTGAGCCACTTCTTCTGC
GAATTGACCGAGGAGAAGCGCGAGGGCTACAAGCGTCTCCTGAAGATGCAAAACCAGCGTGGCGGCCGCGCTCTCTTCCA
GGACATCAAGAAGCCAGCTGAAAGATGAGTGGGGTAAAACCCCAGATGCCATGAAAGCCCCCGTGGCCCTGGGAGAAAAA
GCTGAACCAGGCCCTTTTGGATCTTCATGCCCTGGGTTCTGCCCGCACGGACCCCCATCTCTGTGACTTCCTGGAGACTC
ACTTCCTAGATGAGGAAGTGAAGCTCATCAAGAAGATGGGTGACCACCTGACGAACCTCCGCAGGCTGGGCGGCCCAGAG
GCTGGGCTGGGC

Alignment

ORF - retro_pabe_1814 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.57 %
• Parental protein coverage: 86.24 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MSSQIRQNYS-TDVEAAVNSLVNMYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKM
          MSSQIRQNYS.TDVEAAVNSL.N.YLQASYTYLSLGFYFDR.DVALEGVSHFF.EL.EEKREGY.RLLKM
Retrocopy MSSQIRQNYS>TDVEAAVNSLGNLYLQASYTYLSLGFYFDRNDVALEGVSHFFCELTEEKREGYKRLLKM

Parental  QNQRGGRALFQDIKKPAE-DEWGKTPDAMKAAMAL-EKKLNQALLDLHALGSAHTDPHLCDFLETHFLDE
          QNQRGGRALFQDIKKPAE.DEWGKTPDAMKA..AL.EKKLNQALLDLHALGSA.TDPHLCDFLETHFLDE
Retrocopy QNQRGGRALFQDIKKPAE>DEWGKTPDAMKAPVAL>EKKLNQALLDLHALGSARTDPHLCDFLETHFLDE

Parental  EVKLIKKMGDHLTNLHRLGGPEAGAG
          EVKLIKKMGDHLTNL.RLGGPEAG.G
Retrocopy EVKLIKKMGDHLTNLRRLGGPEAGLG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	2.99 RPM	98.31 RPM
SRP007412_cerebellum	4.62 RPM	54.48 RPM
SRP007412_heart	1.32 RPM	53.34 RPM
SRP007412_kidney	32.72 RPM	966.76 RPM
SRP007412_liver	30.79 RPM	1042.84 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1814 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1814 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1814 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2407
Pan troglodytes	retro_ptro_98

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 301 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000013343	33 retrocopies	retro_btau_1007, retro_btau_1011, retro_btau_1033, retro_btau_1197, retro_btau_1209, retro_btau_1277, retro_btau_1354, retro_btau_1396, retro_btau_1452, retro_btau_1464, retro_btau_1466, retro_btau_1481, retro_btau_1511, retro_btau_1540, retro_btau_1561, retro_btau_1683, retro_btau_1781, retro_btau_1798, retro_btau_1848, retro_btau_250, retro_btau_301, retro_btau_339, retro_btau_340, retro_btau_419, retro_btau_422, retro_btau_520, retro_btau_597, retro_btau_639, retro_btau_649, retro_btau_938, retro_btau_963, retro_btau_993, retro_btau_998,
Canis familiaris	ENSCAFG00000003861	1 retrocopy	retro_cfam_203,
Callithrix jacchus	ENSCJAG00000000250	13 retrocopies	retro_cjac_1171, retro_cjac_1208, retro_cjac_1264, retro_cjac_1643, retro_cjac_2272, retro_cjac_2780, retro_cjac_3113, retro_cjac_3254, retro_cjac_3879, retro_cjac_556, retro_cjac_60, retro_cjac_889, retro_cjac_997,
Cavia porcellus	ENSCPOG00000020558	1 retrocopy	retro_cpor_100,
Dasypus novemcinctus	ENSDNOG00000002455	9 retrocopies	retro_dnov_1096, retro_dnov_1135, retro_dnov_1177, retro_dnov_1737, retro_dnov_2006, retro_dnov_2352, retro_dnov_2678, retro_dnov_473, retro_dnov_993,
Dasypus novemcinctus	ENSDNOG00000004126	5 retrocopies	retro_dnov_1263, retro_dnov_1490, retro_dnov_1760, retro_dnov_2329, retro_dnov_299,
Dasypus novemcinctus	ENSDNOG00000005577	36 retrocopies	retro_dnov_103, retro_dnov_1164, retro_dnov_1215, retro_dnov_130, retro_dnov_1382, retro_dnov_1441, retro_dnov_1515, retro_dnov_1568, retro_dnov_1657, retro_dnov_1812, retro_dnov_1815, retro_dnov_1918, retro_dnov_1991, retro_dnov_2014, retro_dnov_2134, retro_dnov_2187, retro_dnov_236, retro_dnov_2376, retro_dnov_2379, retro_dnov_247, retro_dnov_2575, retro_dnov_2658, retro_dnov_2667, retro_dnov_285, retro_dnov_305, retro_dnov_432, retro_dnov_439, retro_dnov_543, retro_dnov_598, retro_dnov_642, retro_dnov_807, retro_dnov_841, retro_dnov_846, retro_dnov_849, retro_dnov_861, retro_dnov_897,
Dasypus novemcinctus	ENSDNOG00000007848	2 retrocopies	retro_dnov_1049, retro_dnov_1476,
Dasypus novemcinctus	ENSDNOG00000016683	8 retrocopies	retro_dnov_1134, retro_dnov_1329, retro_dnov_2023, retro_dnov_2194, retro_dnov_2228, retro_dnov_56, retro_dnov_757, retro_dnov_886,
Felis catus	ENSFCAG00000003348	37 retrocopies	retro_fcat_101, retro_fcat_1029, retro_fcat_1040, retro_fcat_1059, retro_fcat_1141, retro_fcat_1150, retro_fcat_1295, retro_fcat_1319, retro_fcat_1336, retro_fcat_1359, retro_fcat_139, retro_fcat_1522, retro_fcat_1523, retro_fcat_1602, retro_fcat_1658, retro_fcat_1741, retro_fcat_1747, retro_fcat_1764, retro_fcat_1765, retro_fcat_1766, retro_fcat_1799, retro_fcat_1812, retro_fcat_1901, retro_fcat_297, retro_fcat_298, retro_fcat_315, retro_fcat_343, retro_fcat_50, retro_fcat_533, retro_fcat_536, retro_fcat_620, retro_fcat_675, retro_fcat_68, retro_fcat_778, retro_fcat_918, retro_fcat_927, retro_fcat_964,
Gorilla gorilla	ENSGGOG00000011999	9 retrocopies	retro_ggor_128, retro_ggor_1547, retro_ggor_2039, retro_ggor_25, retro_ggor_2784, retro_ggor_2894, retro_ggor_420, retro_ggor_677, retro_ggor_750,
Loxodonta africana	ENSLAFG00000031248	11 retrocopies	retro_lafr_1003, retro_lafr_1064, retro_lafr_1065, retro_lafr_1069, retro_lafr_1206, retro_lafr_255, retro_lafr_345, retro_lafr_346, retro_lafr_785, retro_lafr_836, retro_lafr_977,
Macaca mulatta	ENSMMUG00000003909	9 retrocopies	retro_mmul_1051, retro_mmul_1125, retro_mmul_1508, retro_mmul_1569, retro_mmul_1617, retro_mmul_1950, retro_mmul_481, retro_mmul_518, retro_mmul_989,
Mustela putorius furo	ENSMPUG00000003304	29 retrocopies	retro_mputfur_1012, retro_mputfur_1026, retro_mputfur_1133, retro_mputfur_1142, retro_mputfur_1150, retro_mputfur_1216, retro_mputfur_1222, retro_mputfur_1225, retro_mputfur_1238, retro_mputfur_1246, retro_mputfur_1268, retro_mputfur_1303, retro_mputfur_1335, retro_mputfur_1521, retro_mputfur_1620, retro_mputfur_195, retro_mputfur_222, retro_mputfur_265, retro_mputfur_350, retro_mputfur_356, retro_mputfur_368, retro_mputfur_482, retro_mputfur_66, retro_mputfur_702, retro_mputfur_741, retro_mputfur_80, retro_mputfur_820, retro_mputfur_906, retro_mputfur_952,
Mus musculus	ENSMUSG00000050708	1 retrocopy	retro_mmus_228,
Nomascus leucogenys	ENSNLEG00000004716	10 retrocopies	retro_nleu_1099, retro_nleu_1332, retro_nleu_1871, retro_nleu_1977, retro_nleu_2028, retro_nleu_2180, retro_nleu_2294, retro_nleu_2715, retro_nleu_272, retro_nleu_290,
Oryctolagus cuniculus	ENSOCUG00000000014	6 retrocopies	retro_ocun_1090, retro_ocun_1627, retro_ocun_223, retro_ocun_357, retro_ocun_530, retro_ocun_982,
Pongo abelii	ENSPPYG00000003173	12 retrocopies	retro_pabe_1034, retro_pabe_1186, retro_pabe_2410, retro_pabe_2483, retro_pabe_2484, retro_pabe_249, retro_pabe_3351, retro_pabe_3406, retro_pabe_35, retro_pabe_3713, retro_pabe_47, retro_pabe_479,
Pongo abelii	ENSPPYG00000010223	11 retrocopies	retro_pabe_1362, retro_pabe_1615, retro_pabe_1690, retro_pabe_1814 , retro_pabe_2514, retro_pabe_291, retro_pabe_3056, retro_pabe_3463, retro_pabe_3626, retro_pabe_3734, retro_pabe_800,
Pan troglodytes	ENSPTRG00000011268	11 retrocopies	retro_ptro_1118, retro_ptro_1307, retro_ptro_1437, retro_ptro_2055, retro_ptro_2619, retro_ptro_2818, retro_ptro_3101, retro_ptro_3195, retro_ptro_328, retro_ptro_645, retro_ptro_98,
Rattus norvegicus	ENSRNOG00000020843	7 retrocopies	retro_rnor_109, retro_rnor_168, retro_rnor_263, retro_rnor_306, retro_rnor_362, retro_rnor_373, retro_rnor_4,
Sus scrofa	ENSSSCG00000003153	33 retrocopies	retro_sscr_1040, retro_sscr_1095, retro_sscr_1101, retro_sscr_1142, retro_sscr_1189, retro_sscr_1214, retro_sscr_1215, retro_sscr_124, retro_sscr_197, retro_sscr_212, retro_sscr_224, retro_sscr_305, retro_sscr_331, retro_sscr_400, retro_sscr_531, retro_sscr_532, retro_sscr_533, retro_sscr_534, retro_sscr_535, retro_sscr_536, retro_sscr_559, retro_sscr_589, retro_sscr_605, retro_sscr_74, retro_sscr_747, retro_sscr_799, retro_sscr_817, retro_sscr_830, retro_sscr_833, retro_sscr_839, retro_sscr_840, retro_sscr_862, retro_sscr_898,
Ictidomys tridecemlineatus	ENSSTOG00000020639	7 retrocopies	retro_itri_1606, retro_itri_1701, retro_itri_1857, retro_itri_24, retro_itri_355, retro_itri_719, retro_itri_741,