RetrogeneDB ID: retro_ocun_331

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: 1:2617674..2618177(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SYPL1
• Ensembl ID: ENSOCUG00000015127
• Aliases: None
• Description: synaptophysin-like 1 [Source:HGNC Symbol;Acc:11507]

Sequence

>retro_ocun_331
TTTCAGGCAGCTCCAAATGTAACTGTGAGTGGTGTGAGTTGGGAAAGTCACGTCCTCACAGGCGATTCCTCTTCTTGGGC
ACAGTTCTATGTTACGTTTGCAGTCTTCATGTTCTTGTACTGCATTGCTGCCCTGCTGTAGGTTGGTTAAAGGAACCTAT
ATCAAGATAGTCGCACACTTCCCATGGTTGATTTTGCTGTTACTCTTGTTGCCATTTTGTTGTGGTTGGTGACCCTTCAG
CCTGGACTAAAGCTCTTATGGATATTAAGGTAGCCGCTGGCCACCATATTGTTCAGGAACTTCTGTCTTGTAGACAGCAG
GAAGTGCATTGATATTTTGGTTCAGTGACTAGTATAGGATTCCTAAATGTATCTGTGAACTTTGAGTCTCTGGACATACT
TTGGGGAGGAATTGTGTGCTTTGTATACCAGGAGGCCAGTTTACACAGTCCATCAAATATTTCTACTGCCCATGGCCAAG
GTGTTCTACCTCTTGCGGGAATA

Alignment

ORF - retro_ocun_331 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.09 %
• Parental protein coverage: 66.02 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  FQAPPNVNVCGVSWDSHVLIGDYSSSAQFYVTFAVFVFLYCIATLLLYVGYTNLYRDSRKLPMVDFVITL
          FQA.PNV.V.GVSW.SHVL.GD.SS.AQFYVTFAVF.FLYCIA..LL.VG..NLY.DSR.LPMVDF..TL
Retrocopy FQAAPNVTVSGVSWESHVLTGDSSSWAQFYVTFAVFMFLYCIAA-LL*VG*RNLYQDSRTLPMVDFAVTL

Parental  VATFLWLVS-TSAWAKALTDIKVSTGHSIVQELLPCQQKDVHCYFGSVTSMGSLNVSVIFGFLNMILWGG
          VA..LWLV...SAW.KAL.DIKV..GH.IVQELL.C.Q..VH.YFGSVTS.G.LNVSV.F..L..ILWGG
Retrocopy VAILLWLVT<PSAWTKALMDIKVAAGHHIVQELLSCRQQEVH*YFGSVTSIGFLNVSVNFESLD-ILWGG

Parental  NAWFVYKETSLHSPSNTSTAHGQGGVPPPAGI
          ...FVY.E.SLHSPSN.STAHGQ.GV.P.AGI
Retrocopy IVCFVYQEASLHSPSNISTAHGQ-GVLPLAGI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	37.25 RPM
SRP017611_kidney	0.00 RPM	130.45 RPM
SRP017611_liver	0.00 RPM	29.98 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_331 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_331 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_331 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000016176	2 retrocopies	retro_cjac_1588, retro_cjac_2483,
Cavia porcellus	ENSCPOG00000009221	1 retrocopy	retro_cpor_239,
Equus caballus	ENSECAG00000009695	1 retrocopy	retro_ecab_340,
Homo sapiens	ENSG00000008282	1 retrocopy	retro_hsap_1817,
Gorilla gorilla	ENSGGOG00000006497	1 retrocopy	retro_ggor_1984,
Myotis lucifugus	ENSMLUG00000014980	3 retrocopies	retro_mluc_1884, retro_mluc_2083, retro_mluc_449,
Macaca mulatta	ENSMMUG00000019593	2 retrocopies	retro_mmul_1251, retro_mmul_1464,
Mus musculus	ENSMUSG00000020570	1 retrocopy	retro_mmus_3470,
Nomascus leucogenys	ENSNLEG00000008861	1 retrocopy	retro_nleu_2720,
Oryctolagus cuniculus	ENSOCUG00000015127	3 retrocopies	retro_ocun_1000, retro_ocun_1569, retro_ocun_331 ,
Otolemur garnettii	ENSOGAG00000008079	2 retrocopies	retro_ogar_1970, retro_ogar_2520,
Ochotona princeps	ENSOPRG00000006755	2 retrocopies	retro_opri_210, retro_opri_448,
Pongo abelii	ENSPPYG00000018292	1 retrocopy	retro_pabe_2370,
Pan troglodytes	ENSPTRG00000019570	2 retrocopies	retro_ptro_1173, retro_ptro_1939,
Rattus norvegicus	ENSRNOG00000009856	2 retrocopies	retro_rnor_2273, retro_rnor_2992,
Sorex araneus	ENSSARG00000013935	1 retrocopy	retro_sara_450,
Ictidomys tridecemlineatus	ENSSTOG00000020871	1 retrocopy	retro_itri_1243,
Tupaia belangeri	ENSTBEG00000009095	2 retrocopies	retro_tbel_2025, retro_tbel_2566,
Tarsius syrichta	ENSTSYG00000013296	2 retrocopies	retro_tsyr_1768, retro_tsyr_775,
Tursiops truncatus	ENSTTRG00000002848	1 retrocopy	retro_ttru_661,