RetrogeneDB ID: retro_mmul_2642

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:135556650..135557183(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.4339
• Ensembl ID: ENSMMUG00000021075
• Aliases: None
• Description: None

Sequence

>retro_mmul_2642
GCTGTAGGTAAAACTTGCCTACTGATCAGTTACACAATCAATGCATTTCCTGGAGAATATATCCCTACTGTCTCTGACAA
TTATTCTGCCAATGTTGTGGTAGATGGAAAACCGGTGAATCTGGGCTTATGGGATATAGCTGGACAAGACGATTATGACA
GATTACGCCCCCATCCTATCCGCAAACAGATGTGTTCTTAATTTGCTTTTCGCTTGTGAGTCCTGCATCATTTGAAAATG
TCCGTGCAAAGTGGTATCCTGAGGTGCGGCAGCACTGTCCCAACACTCCCATCATCCTAGTAGGAACTAAACTTGATCTT
AGGGATGATAAAGACACGGTCGAGAAACTGAAGGAGAAGAAGCTGACTCCCATCACCTATCCGCAGGGTCTAGCCATGGC
TAAGGAGATTGGTGCTGCAAAATACCTGGAGTGTTTGGTGCTCACACAGCGAGGCCTCAAGACAGTGTTTGACAAAGCGA
TCCGAGCTGTCCTCTGCCCACATCCCGTGAAGAAGAAGAGAAAATGCCTGCTG

Alignment

ORF - retro_mmul_2642 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.67 %
• Parental protein coverage: 99.44 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPL-SYPQTDVFLIC
          AVGKTCLLISYT.NAFPGEYIPTV.DNYSANV.VDGKPVNLGLWD.AGQ.DYDRLRP..SYPQTDVFLIC
Retrocopy AVGKTCLLISYTINAFPGEYIPTVSDNYSANVVVDGKPVNLGLWDIAGQDDYDRLRPH<SYPQTDVFLIC

Parental  FSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGA
          FSLVSPASFENVRAKWYPEVR.HCPNTPIILVGTKLDLRDDKDT.EKLKEKKLTPITYPQGLAMAKEIGA
Retrocopy FSLVSPASFENVRAKWYPEVRQHCPNTPIILVGTKLDLRDDKDTVEKLKEKKLTPITYPQGLAMAKEIGA

Parental  VKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLL
          .KYLEC..LTQRGLKTVFD.AIRAVLCP.PVKK.KRKCLL
Retrocopy AKYLECLVLTQRGLKTVFDKAIRAVLCPHPVKK-KRKCLL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	1.57 RPM	250.10 RPM
SRP007412_brain_prefrontal_cortex	0.95 RPM	187.62 RPM
SRP007412_cerebellum	0.90 RPM	177.26 RPM
SRP007412_heart	2.12 RPM	88.62 RPM
SRP007412_kidney	0.70 RPM	125.94 RPM
SRP007412_liver	1.43 RPM	73.03 RPM
SRP007412_testis	1.43 RPM	39.58 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2642 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2642 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2642 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4910
Pan troglodytes	retro_ptro_3274
Gorilla gorilla	retro_ggor_217
Pongo abelii	retro_pabe_3818

---

Parental genes homology:

Parental genes homology involve 10 parental genes, and 29 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000009233	2 retrocopies	retro_btau_1601, retro_btau_332,
Canis familiaris	ENSCAFG00000015716	1 retrocopy	retro_cfam_496,
Gorilla gorilla	ENSGGOG00000026733	2 retrocopies	retro_ggor_2110, retro_ggor_217,
Macaca mulatta	ENSMMUG00000018854	2 retrocopies	retro_mmul_1346, retro_mmul_210,
Macaca mulatta	ENSMMUG00000021075	4 retrocopies	retro_mmul_1310, retro_mmul_1964, retro_mmul_2642 , retro_mmul_721,
Macaca mulatta	ENSMMUG00000022009	8 retrocopies	retro_mmul_1449, retro_mmul_1612, retro_mmul_1685, retro_mmul_1900, retro_mmul_1932, retro_mmul_24, retro_mmul_349, retro_mmul_598,
Oryctolagus cuniculus	ENSOCUG00000009956	1 retrocopy	retro_ocun_305,
Pan troglodytes	ENSPTRG00000018910	4 retrocopies	retro_ptro_1288, retro_ptro_3044, retro_ptro_3274, retro_ptro_36,
Tupaia belangeri	ENSTBEG00000007272	4 retrocopies	retro_tbel_1796, retro_tbel_2564, retro_tbel_4296, retro_tbel_9,
Xenopus tropicalis	ENSXETG00000027593	1 retrocopy	retro_xtro_1,