RetrogeneDB ID: retro_mmul_1734

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 3:160775046..160775733(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.9780
• Ensembl ID: ENSMMUG00000013157
• Aliases: None
• Description: acyl-protein thioesterase 1 [Source:RefSeq peptide;Acc:NP_001253217]

Sequence

>retro_mmul_1734
ATGTGTGGCAATGCGTGTCTGCTCTGCGGCCCACCATAGGGTCTGCTGCCCTGAAGGCCACAGCAGTGGTGATTTTTCTT
CATGGATGGGGAAATATTGGGCACAGATGGGCAGAGACTTTGCAGGTATCAGAAGTTCATATCAAATGTATCTCCCCACA
TGTGCCAATTGTGCCCATGACATTAAACATGAACATGGCTATGCCTTCTTGGTTTGATGTTATTGGGCTTTCACCAGATT
CCTAGGAGGTGGAAACTGGAATTAAATGGGCAGCAGAAAATGTAAAACCTTTGGTAGATCAAGAGGTGTAGAATGGCATT
CTTTCTGACAGAATTATTTCGGGAGGATTTTCTCAGGGAGGAGCTTTATTTTTATGTACTGCTCTTACCACACAGCAGAA
ACTGGCAGGTGTCACTGCAGGTGACTGCTGGCTTTCACTTTGGGCTTCCTTTCCAAAGGGTCCTATTGGTGGTACTAATA
GAGATATTTATATTCTACAGTGCCATGGAGATTGTGACCCATTCGTACCCCAATGTTTGGTTTCCTTATTTTTTTCTTAT
TGTTTTATATTGGTAAATCTAGCCAATGTAAACTTTAAAACCTGTGAAAGCATAATGCACACTTCATGTCAACAGAAAAT
GATTAGATGTCAAGCAATTCATTGATAAAATTCTACTTCCAATTGAT

Alignment

ORF - retro_mmul_1734 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.67 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MCGNN-MSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNMAM
          MCGN...S...P.I..AA.KATA.VIFLHG.G..GH.WAE........HIK.I.PH.P..P.TLNMNMAM
Retrocopy MCGNA<VSALRPTIGSAALKATAVVIFLHGWGNIGHRWAETLQ-VSEVHIKCISPHVPIVPMTLNMNMAM

Parental  PSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGV
          PSWFD.IGLSPDS.E.E.GIK.AAEN.K.L.DQEV.NGI.S.RII.GGFSQGGAL.L.TALTTQQKLAGV
Retrocopy PSWFDVIGLSPDS*EVETGIKWAAENVKPLVDQEV*NGILSDRIISGGFSQGGALFLCTALTTQQKLAGV

Parental  TALSCWLPLRASFPQGPVGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPVNVTFKTYEGMMHS
          TA..CWL.L.ASFP.GP.GG.NRDI.ILQCHGDCDP.VP....SL.......LVN..NV.FKT.E..MH.
Retrocopy TAGDCWLSLWASFPKGPIGGTNRDIYILQCHGDCDPFVPQCLVSLFFSYCFILVNLANVNFKTCESIMHT

Parental  SCQQEM-MDVKQFIDKLLPPID
          SCQQ.M..DVKQFIDK.L.PID
Retrocopy SCQQKM>LDVKQFIDKILLPID

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	9.86 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	10.71 RPM
SRP007412_cerebellum	0.00 RPM	15.76 RPM
SRP007412_heart	0.00 RPM	15.31 RPM
SRP007412_kidney	0.00 RPM	19.84 RPM
SRP007412_liver	0.00 RPM	16.19 RPM
SRP007412_testis	0.00 RPM	79.57 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_1734 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_1734 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_1734 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3897
Gorilla gorilla	retro_ggor_2626
Pongo abelii	retro_pabe_3177
Callithrix jacchus	retro_cjac_3100

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 53 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000006978	1 retrocopy	retro_cfam_523,
Callithrix jacchus	ENSCJAG00000011562	2 retrocopies	retro_cjac_1260, retro_cjac_3100,
Cavia porcellus	ENSCPOG00000022715	3 retrocopies	retro_cpor_142, retro_cpor_549, retro_cpor_782,
Dipodomys ordii	ENSDORG00000001479	1 retrocopy	retro_dord_88,
Equus caballus	ENSECAG00000016530	1 retrocopy	retro_ecab_238,
Echinops telfairi	ENSETEG00000001727	2 retrocopies	retro_etel_612, retro_etel_791,
Homo sapiens	ENSG00000120992	3 retrocopies	retro_hsap_3078, retro_hsap_3485, retro_hsap_3897,
Myotis lucifugus	ENSMLUG00000008208	1 retrocopy	retro_mluc_1683,
Macaca mulatta	ENSMMUG00000013157	3 retrocopies	retro_mmul_1734 , retro_mmul_2459, retro_mmul_2474,
Mus musculus	ENSMUSG00000025903	1 retrocopy	retro_mmus_3700,
Nomascus leucogenys	ENSNLEG00000001027	4 retrocopies	retro_nleu_1137, retro_nleu_2015, retro_nleu_2817, retro_nleu_2869,
Oryctolagus cuniculus	ENSOCUG00000006751	3 retrocopies	retro_ocun_1510, retro_ocun_1623, retro_ocun_1679,
Otolemur garnettii	ENSOGAG00000003767	3 retrocopies	retro_ogar_1528, retro_ogar_1530, retro_ogar_1532,
Pongo abelii	ENSPPYG00000018590	3 retrocopies	retro_pabe_2550, retro_pabe_3177, retro_pabe_3565,
Pteropus vampyrus	ENSPVAG00000005246	2 retrocopies	retro_pvam_224, retro_pvam_838,
Rattus norvegicus	ENSRNOG00000008320	3 retrocopies	retro_rnor_1747, retro_rnor_2612, retro_rnor_406,
Tupaia belangeri	ENSTBEG00000014207	8 retrocopies	retro_tbel_1839, retro_tbel_2439, retro_tbel_2478, retro_tbel_2907, retro_tbel_3127, retro_tbel_3466, retro_tbel_371, retro_tbel_4145,
Tarsius syrichta	ENSTSYG00000012350	6 retrocopies	retro_tsyr_1287, retro_tsyr_1303, retro_tsyr_1465, retro_tsyr_1901, retro_tsyr_1996, retro_tsyr_2158,
Tursiops truncatus	ENSTTRG00000011836	3 retrocopies	retro_ttru_1643, retro_ttru_169, retro_ttru_291,