RetrogeneDB ID: retro_fcat_445

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: A3:104743644..104744290(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: UNG
• Ensembl ID: ENSFCAG00000008349
• Aliases: None
• Description: uracil-DNA glycosylase [Source:HGNC Symbol;Acc:12572]

Sequence

>retro_fcat_445
AAGAAGCACCTTAGCACAGAGTTTGGGAAACCATATTTTATAAAGCTCATGGTGTCTGTTGCAGAAAAAAGAAAACATTA
CACTATTTACCCACTCCCACATCAAATCTTCAGTTGGACCCAAATGTGTGACATAAGACATGTGAAGGTTGTCATCCTGG
GACAAGACCAGTATCATGGACCCAATCAAGCACACAGGCTCTGCTTTGGTGTTCAAAGACCCATCCCACCGCCACCCAGT
TTGGAAAACATATATAAAGAGCTGTCTACAGACATAGATGGTTTTGTTCATCCTGCTCACAGAGATTTATCCGGGTGGGC
CAGACAAGGTGCTGTTCTCTTACTCTAAGCTGTCCTCACATTCTGGGCACATCAGGCTAATTCTCATAAAGAGAGAGGAT
GGGAGCAATTTACTGGTGTTTTGTGTCCTGGCTAAATCAGAACTCTGGAGGCTTGTCTTCCTGCTCTGGGGCTCTTAGGC
TCAGAAGAGAGGCAGTGCCATCCATAGGAAAGGCCACCATGTGCTGCAGACTGCTCACCCCACACCGCTGTCGGTATACA
GAGGGTTCTTTGGATATAGACATTTCTCTAAAACCAATGAGTTGCTGCAAAAGTCTGGCAAGGAGCCCATCAACTGGAAA
AGTCTG

Alignment

ORF - retro_fcat_445 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 84.86 %
• Parental protein coverage: 69.81 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  KKHLSAEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIRHVKVVILGQDPYHGPNQAHGLCFS
          KKHLS.EFGKPYFIKLM..VAE.RKHYT.YP.PHQ.F.WTQMCDIRHVKVVILGQD.YHGPNQAH.LCF.
Retrocopy KKHLSTEFGKPYFIKLMVSVAEKRKHYTIYPLPHQIFSWTQMCDIRHVKVVILGQDQYHGPNQAHRLCFG

Parental  VQRPIPPPPSLENIYKELSTDIDGFVHPGHGDLSGWAKQG-VLLLNAVLTVRAHQANSHKERGWEEFTDA
          VQRPIPPPPSLENIYKELSTDIDGFVHP.H.DLSGWA.QG.VLLL.AVLT..AHQANSHKERGWE.FT..
Retrocopy VQRPIPPPPSLENIYKELSTDIDGFVHPAHRDLSGWARQGAVLLL*AVLTFWAHQANSHKERGWEQFTGV

Parental  V-VSWLNHNSSG-LVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGK
          ..VSWLN.NS.G.LVFLLWGS.AQK.GSAI.RK.HHVLQTAHP.PLSVYRGFFG.RHFSKTNELLQKSGK
Retrocopy L<VSWLNQNSGG<LVFLLWGS*AQKRGSAIHRKGHHVLQTAHPTPLSVYRGFFGYRHFSKTNELLQKSGK

Parental  EPINWKDL
          EPINWK.L
Retrocopy EPINWKSL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	5.16 RPM
SRP017611_kidney	0.00 RPM	11.23 RPM
SRP017611_liver	0.00 RPM	3.44 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_445 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_445 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 18 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016525	1 retrocopy	retro_amel_153,
Canis familiaris	ENSCAFG00000011144	1 retrocopy	retro_cfam_1567,
Callithrix jacchus	ENSCJAG00000010134	2 retrocopies	retro_cjac_1467, retro_cjac_520,
Cavia porcellus	ENSCPOG00000004634	3 retrocopies	retro_cpor_1339, retro_cpor_6, retro_cpor_863,
Dasypus novemcinctus	ENSDNOG00000005335	2 retrocopies	retro_dnov_1001, retro_dnov_627,
Equus caballus	ENSECAG00000008080	1 retrocopy	retro_ecab_747,
Felis catus	ENSFCAG00000008349	1 retrocopy	retro_fcat_445 ,
Macropus eugenii	ENSMEUG00000015792	3 retrocopies	retro_meug_1594, retro_meug_1877, retro_meug_2077,
Myotis lucifugus	ENSMLUG00000010755	3 retrocopies	retro_mluc_1305, retro_mluc_2060, retro_mluc_989,
Macaca mulatta	ENSMMUG00000006957	2 retrocopies	retro_mmul_1564, retro_mmul_2115,
Mustela putorius furo	ENSMPUG00000003463	1 retrocopy	retro_mputfur_1592,
Nomascus leucogenys	ENSNLEG00000001442	3 retrocopies	retro_nleu_1325, retro_nleu_1950, retro_nleu_2802,
Oryctolagus cuniculus	ENSOCUG00000003145	1 retrocopy	retro_ocun_1767,
Otolemur garnettii	ENSOGAG00000007441	2 retrocopies	retro_ogar_1593, retro_ogar_2716,
Pongo abelii	ENSPPYG00000004929	3 retrocopies	retro_pabe_1354, retro_pabe_1355, retro_pabe_2792,
Pan troglodytes	ENSPTRG00000005419	1 retrocopy	retro_ptro_1108,
Sus scrofa	ENSSSCG00000009938	1 retrocopy	retro_sscr_1202,
Ictidomys tridecemlineatus	ENSSTOG00000006894	1 retrocopy	retro_itri_661,