RetrogeneDB ID: retro_fcat_1546

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: D3:42961769..42962092(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PTS
• Ensembl ID: ENSFCAG00000024702
• Aliases: None
• Description: 6-pyruvoyltetrahydropterin synthase [Source:HGNC Symbol;Acc:9689]

Sequence

>retro_fcat_1546
GGTAAATGCCACAATCCCAATGCCATGGACACAAGTATAAAGTTGTGGTGACTGTACATAGAGAGACTGATCCTGTTACA
GGAGTGGTTATGAATTTGACCAACCTCAAAGGGTATATGGAGGAGACAGTTATGAAGCCCCTTGATCATAATAATCTGGA
TTTGGATGTGCCATACTTTGCAGATGTTGTAAACCTGACAGAAAATATAGCTGTAGATATCTGGGAAAACCTCCAGAAAT
CTCTTCCCCTGGGGGGGGGGGGGGTTCTTTATTAAGTAAAAGTATATGAGACTGACAATAATACTGTAGTCTATAAAGAA
GAA

Alignment

ORF - retro_fcat_1546 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.23 %
• Parental protein coverage: 71.43 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GKCNNPNG-HGHNYKVVVTVHGEIDPVTGMVMNMTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTEN
          GKC.NPN..HGH.YKVVVTVH.E.DPVTG.VMN.T.LK.YMEE..MKPLDH.NLDLDVPYFADVV..TEN
Retrocopy GKCHNPNA<HGHKYKVVVTVHRETDPVTGVVMNLTNLKGYMEETVMKPLDHNNLDLDVPYFADVVNLTEN

Parental  VAVYIWENLQKFLP---MGVLYKVKVYETDNNVVVYKGE
          .AV.IWENLQK.LP......LY.VKVYETDNN.VVYK.E
Retrocopy IAVDIWENLQKSLPXXXXXXLY*VKVYETDNNTVVYKEE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	4.36 RPM
SRP017611_kidney	0.00 RPM	8.24 RPM
SRP017611_liver	0.00 RPM	4.14 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_1546 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_1546 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003968	3 retrocopies	retro_amel_1001, retro_amel_1480, retro_amel_691,
Bos taurus	ENSBTAG00000003770	3 retrocopies	retro_btau_1182, retro_btau_1762, retro_btau_682,
Canis familiaris	ENSCAFG00000013915	2 retrocopies	retro_cfam_1386, retro_cfam_1859,
Dasypus novemcinctus	ENSDNOG00000014823	1 retrocopy	retro_dnov_1747,
Echinops telfairi	ENSETEG00000008145	2 retrocopies	retro_etel_1924, retro_etel_2039,
Felis catus	ENSFCAG00000024702	3 retrocopies	retro_fcat_1546 , retro_fcat_212, retro_fcat_564,
Myotis lucifugus	ENSMLUG00000023388	1 retrocopy	retro_mluc_946,
Macaca mulatta	ENSMMUG00000015255	1 retrocopy	retro_mmul_995,
Sorex araneus	ENSSARG00000001975	2 retrocopies	retro_sara_163, retro_sara_72,
Sus scrofa	ENSSSCG00000015040	1 retrocopy	retro_sscr_284,
Tursiops truncatus	ENSTTRG00000010526	1 retrocopy	retro_ttru_1710,
Vicugna pacos	ENSVPAG00000000061	1 retrocopy	retro_vpac_363,