RetrogeneDB ID: retro_fcat_1423

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: D1:105155399..105156687(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENO2
• Ensembl ID: ENSFCAG00000004282
• Aliases: None
• Description: enolase 2 (gamma, neuronal) [Source:HGNC Symbol;Acc:3353]

Sequence

>retro_fcat_1423
ATGGCCATGCAGAAAATCTTTACCTGGGAAATCCTGGACTCCAGGGACAACCCCATGGTAGATGTGGTCCTACACATGGT
CAGGGGCCAATTCCAAGCAGCTGTGCCCAGAAGAGCTTCCACAGGTATCTATGAAACTCTGAAACTGAGAGATGGAGACA
AATCCTGCTCCCTTAGGAAAGGGATTCTGAAGGCTGTGGGACACATCAATAAGACCCTGGGCCCCACTCTGCTGTAAAAT
AAACTAAGCATTGTGGATCAAGAAAAAGTTGACAAATATATGATTGAGCTGGATGGGACTGAGAATATGTCCATGTTTGG
GGTCACTGCCATCCTGGGTGTATCCTTGGCCGTGTGCAAGGCTGGTGCAGCCAAGAAGGGGGTCATGCTCTACTGGCACA
TCACAGACCTCGCTGGGAACCCAGACTTGGTCCTCCCAGTCCCTGCCTTTGATGTGATCAGTCGGGGCTCCCATGTTGGA
AACAAGCTGGCCACACAGGAGTTCATTTTTCTGCCCATGGGAGCCAGTTCCTTCAAAGAAGCCATGCACATTGGCACTGA
GGTCTACCACCACCTCAAGGCGGTCATCAAGGCGAAGAATGGGAAGGATGCCACCAATCTGGGCAATGAGAGCAGCTTTG
CACCCAACATCCTGGAGAACAGTGAAGCCCTGGAGCTACTGAAGACAGCCATCCAGGAAGCTGGTTACCCAGACAAGGTG
GTGATTGGCATGGATGGGACTGCATCTGAGTTCTATTGCAACAGGAAGTACGATTTTGACTTCAAGTCACCTGATGACTG
CACTGCACACCACTGGGGAGATGCTGGGGGAGCAGTATAAGAGTTTCATCAAGAATCACCCTGTGGTCTTCATCAAGGAC
CCCTTTAGCTAGGGTGACTGGGTCACCTGTATCTCATTCCCCTTGGTGATTGACATCCAGATCATTGGGGATGACCTCAC
AGTCACCAACCCCAAGAGGATTGCCCAAGCCATTGAGAAAAAGGCCTGCAACTGGTGCTGCTGAAGGTCAACCAGATTGG
CTCAGTGACCGAGTCCATCCAGGCCTGCAAACTGGCCTAATCGAATGGCAGGGGTGATGATGAGCCACCACTCCGGGGAG
ACTGAGGATGCATTCATTGTTGACCTCATGGTAGGGCTCTGCATGGGATAGATGAAGACTGATGCCTCCTGCTGCTCAGA
GCACCTGGTCAAATACAACCAGCTCATGTAGATTGAGGAGGCTCTTGGGGACAAGGCTGTCTTTGCTAGACACAAGGCCC
CAAGACCC

Alignment

ORF - retro_fcat_1423 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 63.13 %
• Parental protein coverage: 99.31 %
• Number of stop codons detected: 6
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHIN
          M...KI...EILDSR.NP.V.V.L....G.F.AAVP..ASTGIYE.L.LRDGDK...L.KG.LKAV.HIN
Retrocopy MAMQKIFTWEILDSRDNPMVDVVLHMVRGQFQAAVPRRASTGIYETLKLRDGDKSCSLRKGILKAVGHIN

Parental  TTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGN
          .T..P.L....LS.V.QEK.D..M.ELDGTEN.S.FG..AILGVSLAVCKAGAA.....LY.HI..LAGN
Retrocopy KTLGPTLL*NKLSIVDQEKVDKYMIELDGTENMSMFGVTAILGVSLAVCKAGAAKKGVMLYWHITDLAGN

Parental  SDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDE
          .DL.LPVPAF.VI..GSH.GNKLA.QEF..LP.GA.SF..AM..G.EVYH.LK.VIK.K.GKDATN.G.E
Retrocopy PDLVLPVPAFDVISRGSHVGNKLATQEFIFLPMGASSFKEAMHIGTEVYHHLKAVIKAKNGKDATNLGNE

Parental  GGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFHRDGKYDLDFKSPADPSRYITGDQLGALY
          ..FAPNILENSEALEL.K.AI..AGY..K.VIGMD..ASEF....KYD.DFKSP.D......GD..GA..
Retrocopy SSFAPNILENSEALELLKTAIQEAGYPDKVVIGMDGTASEFYCNRKYDFDFKSPDDCTAHHWGDAGGAV-

Parental  QDFVRDYP-VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACN-CLLLKVNQIG
          ..F....P.VV.I.DPF...DW.....F.....IQI.GDDLTVTNPKRI..A.E.KACN...LLKVNQIG
Retrocopy *EFHQESP>VVFIKDPFS*GDWVTCISFPLVIDIQIIGDDLTVTNPKRIAQAIEKKACN<LVLLKVNQIG

Parental  SVTEAIQACKLAQENGWG-VMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL
          SVTE.IQACKLA..NG.G..M..H.SGETED.FI.DL.VGLC.G..KT.A.C.SE.L.KYNQLM.IEE.L
Retrocopy SVTESIQACKLA*SNGRG>MMSHH-SGETEDAFIVDLMVGLCMG*MKTDASCCSEHLVKYNQLM*IEEAL

Parental  GDEARFAGHNFRNP
          GD.A.FA.H....P
Retrocopy GDKAVFARHKAPRP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	504.54 RPM
SRP017611_kidney	0.00 RPM	5.15 RPM
SRP017611_liver	0.00 RPM	1.21 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_1423 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_1423 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 11 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000014523	1 retrocopy	retro_cfam_320,
Echinops telfairi	ENSETEG00000007582	8 retrocopies	retro_etel_1077, retro_etel_1696, retro_etel_1837, retro_etel_2120, retro_etel_227, retro_etel_286, retro_etel_30, retro_etel_544,
Felis catus	ENSFCAG00000004282	1 retrocopy	retro_fcat_1423 ,
Microcebus murinus	ENSMICG00000001774	1 retrocopy	retro_mmur_362,