RetrogeneDB ID: retro_chof_926

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_169692:691..1423(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCHOG00000003733
• Aliases: None
• Description: None

Sequence

>retro_chof_926
ATGTCAGGAAAAGACCGAATTGAGATCTTTCCCTTGTGAAGGGCATAGACCACCATGAAGGCTTGATTAAAAGGAGTGCA
GACAGGTCGAAACCTCCTGAAGAAAAATCTGATGCCTTGACTCTTCGATTTCAACCTAAACAAGATAATAGAGACTAAAA
TGTTGGTGGGTGAAGTGATGAGAGAAGCTGCCTTTTCACTTGCTAAGGCCAAGTTCACAGCTGGGGACTTCAGCACCAGT
TATCCAAAATGTGAATAAAGACCAACTGAAGATTCATGCAAAGAATAATAATGTAGCAGGAGTATCTTGCCAGTGTTTGA
ACATTGCCATGAAGGAACTGACAGTTATGAACTAATTGGCTTAGCCAGAGGTGGGGAACAACTGGCTAAGTTAAAGAGAA
ATTATGCCAAAGCAGTGCAGCTACTGGTGGAACTAGCTTCACTGCAGACTTCCTATGTTACTCTGGATGAAGCTATTAAG
ATAACCAACAGGCATGTAAATGCCACTGAACATGTCATCCTTCCTTGGATTGAACAACCCCTTGCTTATATCATCACAGA
GCTGGATGAGAGAGAGCAAGAAGAGTTCTATAGGTTAAAGAAAATACAAGAGAAGAAAAAGATTTTCAAAGAAACATCCG
AGAAGGAATTGGAGAAATGGAGAGCAACTGGGGAGGCGATGGAGCTGGCTAATCCTCTGGTTGAGGAGAAGGATGAAGAG
CTTCTGTTTGAA

Alignment

ORF - retro_chof_926 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.3 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGEVMREAA-FSL
          MSGKDRIEIFP...A.T.MKA.LKG.QTGRNLL..K.......F...L.KIIETKML.GEVMREAA.F.L
Retrocopy MSGKDRIEIFPL*RA*TTMKA*LKGVQTGRNLL--KKNLMP*LFDFNLNKIIETKMLVGEVMREAA>FHL

Parental  AEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVT-LPVFEHYHEGTDSYELTGLARGGEQLAKLKRNY
          .......G..S..VIQNVNK.Q.KI.AK..NVAGV..LPVFEH.HEGTDSYEL.GLARGGEQLAKLKRNY
Retrocopy LRPSSQLGT-SAPVIQNVNKDQLKIHAKNNNVAGVS<LPVFEHCHEGTDSYELIGLARGGEQLAKLKRNY

Parental  AKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDEREREEFYRLKKIQEK
          AKAV.LLVELASLQTS.VTLDEAIKITNR.VNA.EHVI.P.IE..LAYIITELDERE.EEFYRLKKIQEK
Retrocopy AKAVQLLVELASLQTSYVTLDEAIKITNRHVNATEHVILPWIEQPLAYIITELDEREQEEFYRLKKIQEK

Parental  KKILKEKFEKDLEQRRAAGEVMEPANLLAEEKDEDLLFE
          KKI.KE..EK.LE..RA.GE.ME.AN.L.EEKDE.LLFE
Retrocopy KKIFKETSEKELEKWRATGEAMELANPLVEEKDEELLFE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_926 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008240	1 retrocopy	retro_amel_332,
Bos taurus	ENSBTAG00000016309	2 retrocopies	retro_btau_1757, retro_btau_408,
Canis familiaris	ENSCAFG00000016369	2 retrocopies	retro_cfam_1186, retro_cfam_999,
Choloepus hoffmanni	ENSCHOG00000003733	5 retrocopies	retro_chof_1229, retro_chof_2711, retro_chof_54, retro_chof_926 , retro_chof_938,
Cavia porcellus	ENSCPOG00000009085	1 retrocopy	retro_cpor_36,
Felis catus	ENSFCAG00000011078	1 retrocopy	retro_fcat_632,
Myotis lucifugus	ENSMLUG00000006244	5 retrocopies	retro_mluc_2345, retro_mluc_442, retro_mluc_540, retro_mluc_666, retro_mluc_94,
Macaca mulatta	ENSMMUG00000021418	1 retrocopy	retro_mmul_1159,
Monodelphis domestica	ENSMODG00000009896	5 retrocopies	retro_mdom_1196, retro_mdom_1522, retro_mdom_1730, retro_mdom_390, retro_mdom_594,
Mustela putorius furo	ENSMPUG00000007002	2 retrocopies	retro_mputfur_1381, retro_mputfur_748,
Otolemur garnettii	ENSOGAG00000015052	1 retrocopy	retro_ogar_966,
Sus scrofa	ENSSSCG00000002288	1 retrocopy	retro_sscr_357,
Ictidomys tridecemlineatus	ENSSTOG00000027710	1 retrocopy	retro_itri_383,
Vicugna pacos	ENSVPAG00000005696	1 retrocopy	retro_vpac_232,
Drosophila melanogaster	FBgn0040377	1 retrocopy	retro_dmel_70,