RetrogeneDB ID: retro_chof_1719

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_365686:281..1137(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MRPL15
• Ensembl ID: ENSCHOG00000005299
• Aliases: None
• Description: mitochondrial ribosomal protein L15 [Source:HGNC Symbol;Acc:14054]

Sequence

>retro_chof_1719
AGCAATCCCAGCGCGGGCAGTAGGGCTGGGGCGCTTCTTCTGCTCTAGGCTTCACTGTGTGTCAGCCTCACCAACTTAAA
GCTGAACCCCAGTTCGATGAAACTAGAGAGAAGACCAAAGCGTAGGAGAAGAGGTGGGAAATGTGGGAGAGGCTGTGAAA
GAGAAAGGCAAAGGGGCTCCGACTGGGCTTTGAAGGAGGCCAGACTCCATTTTACACCTGAATCCCAAAATATGGGTTTG
ACAAAGGACATAGCTTCAGACACCAGTATTAACCATTAAGTCTCAATAGACTGCAGTATCTTAACGATTTGGGTCAAGTT
ACTCCTACTCAACCTACTAACTTAACCCAGCTTGTCAATGGGAGAGGTGTGATTGTCTAGCCACTTAAAAGGGATTATGG
TGTTCAGATTGTAGAAGAGGGGGCTGACACCTTTCAGGCCAAAGCTAATATTGAAGTACAGTTGGCTTCAAAACTAGCCG
TTGTTGCAACTGAAAAAAATGGTGGCATTGCTAACGACAGCCTTTAATGATCCAAGGAGTCTTGAAATTCTGTGCAAGCC
TGTTCCATTCTTTTTGCATGGAGAACCCTTCCAAAATGTATGCTTCTACCTAAATCCCTGATGCCCTATTATTCTGATGC
AAAGAACTGTGGCTACCAGCAGATCCTGGCGAATTTCCTGAAGCAAGACTCGAGCTTGCCAAGAAGTACAGTTATATTGT
ACCTGGTATCCCCAAACATGAGCTCTTCTGGATGCTAAGCACCTGAAAGGACCCAAGGCAGATATTCTTTGGTTTTGCTC
CAGGATGGGTAGTGAACATGGCTGATAAGAAAATCTTAAAACCCACAGATGAGAAT

Alignment

ORF - retro_chof_1719 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.55 %
• Parental protein coverage: 99.65 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  AGPIRGAGAGALDLLRGLPRVSLGNLKPNPGSRKPARRPRGRRRGRKCGRGHKGERQ-RGTRPRLGFEGG
          ..P..G..AGAL.LL.....VSL.NLK.NP.S.K..RRP...RR.R....G...ER.......RLGFEGG
Retrocopy SNPSAGSRAGALLLL*ASLCVSLTNLKLNPSSMKLERRPK--RRRRGGKCGRGCERE<KAKGLRLGFEGG

Parental  QTPFYLRIPKYGFNEGHSFRRQY-QLSLNRLQYLI-LGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQL
          QTPFY..IPKYGF..GHSFR.QY..LSLNRLQYL..LG.V.PTQP..LTQLVNGRGV...PLKRDYGVQ.
Retrocopy QTPFYT*IPKYGFDKGHSFRHQY*PLSLNRLQYLNDLGQVTPTQPTNLTQLVNGRGVIV*PLKRDYGVQI

Parental  VEEGADTFKAKVNIEVQLASELAIAAIEKNGGV-VTTAFYDPRSLEILCKPVPFFLRGQP-IPKRMLPPE
          VEEGADTF.AK.NIEVQLAS.LA..A.EKNGG...TTAF.DPRSLEILCKPVPFFL.G.P..PK.ML.P.
Retrocopy VEEGADTFQAKANIEVQLASKLAVVATEKNGGI>LTTAFNDPRSLEILCKPVPFFLHGEP<LPKCMLLPK

Parental  SLVPYYTDAKNRGYL-ADPGKFPEARLELARKYGYILPDITKDELFRMLSTRKDPRQIFFGLAPGWVVNM
          SL.PYY.DAKN.GY..ADPG.FPEARLELA.KY.YI.P.I.K.ELF.MLST.KDPRQIFFG.APGWVVNM
Retrocopy SLMPYYSDAKNCGYQ<ADPGEFPEARLELAKKYSYIVPGIPKHELFWMLST*KDPRQIFFGFAPGWVVNM

Parental  ADKKILKPTDEH
          ADKKILKPTDE.
Retrocopy ADKKILKPTDEN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1719 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000001174	1 retrocopy	retro_btau_324,
Canis familiaris	ENSCAFG00000006988	2 retrocopies	retro_cfam_1573, retro_cfam_511,
Choloepus hoffmanni	ENSCHOG00000005299	3 retrocopies	retro_chof_1379, retro_chof_1719 , retro_chof_746,
Callithrix jacchus	ENSCJAG00000016719	1 retrocopy	retro_cjac_2230,
Dasypus novemcinctus	ENSDNOG00000017664	1 retrocopy	retro_dnov_364,
Erinaceus europaeus	ENSEEUG00000001454	2 retrocopies	retro_eeur_128, retro_eeur_707,
Echinops telfairi	ENSETEG00000001724	1 retrocopy	retro_etel_1304,
Mustela putorius furo	ENSMPUG00000010533	1 retrocopy	retro_mputfur_149,
Mus musculus	ENSMUSG00000033845	2 retrocopies	retro_mmus_1709, retro_mmus_3534,
Ornithorhynchus anatinus	ENSOANG00000007286	1 retrocopy	retro_oana_114,
Otolemur garnettii	ENSOGAG00000003768	1 retrocopy	retro_ogar_534,
Ochotona princeps	ENSOPRG00000000921	2 retrocopies	retro_opri_241, retro_opri_364,
Rattus norvegicus	ENSRNOG00000008566	2 retrocopies	retro_rnor_1344, retro_rnor_2785,
Sus scrofa	ENSSSCG00000030578	1 retrocopy	retro_sscr_617,
Tarsius syrichta	ENSTSYG00000014106	1 retrocopy	retro_tsyr_37,
Tursiops truncatus	ENSTTRG00000011844	2 retrocopies	retro_ttru_1139, retro_ttru_733,