RetrogeneDB ID: retro_ptro_1635

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 2B:122286577..122286919(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSPTRG00000034506
• Aliases: None
• Description: None

Sequence

>retro_ptro_1635
ATAAAGACTTTTCTGGGATTAAGAGGGCTGTTTCTTCTCCATTACTTTATACGGACCCGTACTGGGGACTTGTCAGCTGT
TCAAGTACAACGCACCCAGTTTTGGTTCTGTACCAGGATTAGGCCTACAATATTTCAGAATTCATATACAAACCCCAATA
AAGTGTTAAAGGAGATGACTGCCCTATAACCTATGTTTTGCTGAATGTTTACCATGAGTTTTTTTTTTACCATCCTCATG
AGTATGGTATTGTAACTGAAACTCTCCAGGAAAATTCCTCTGCTTAAAACTAAAATCAAGTGTATCTCAGGAAACTCTAC
TGTCCCATCTGAAATGCCTCTG

Alignment

ORF - retro_ptro_1635 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 59.48 %
• Parental protein coverage: 92.62 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MKTILGFKGLFYLHSLIWTCAGDWSAIQVHCTQFWFFARIKPTIFYNLYVNPDEVF-LGDGCHVTHVLPN
          .KT.LG..GLF.LH..I.T..GD.SA.QV..TQFWF..RI.PTIF.N.Y.NP..V...GD.C..T.VL.N
Retrocopy IKTFLGLRGLFLLHYFIRTRTGDLSAVQVQRTQFWFCTRIRPTIFQNSYTNPNKVL<KGDDCPITYVLLN

Parental  VYYE-FFYHPHDCGIVTQPLQQ-VLLLKTKIKYISRDSTVRSEMPL
          VY.E....HPH..GIVT..LQ....LLKTKIK.IS..STV.SEMPL
Retrocopy VYHEXXXXHPHEYGIVTETLQE>IPLLKTKIKCISGNSTVPSEMPL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.09 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.03 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_1635 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_1635 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_1635 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Gorilla gorilla	retro_ggor_1709
Pongo abelii	retro_pabe_2101

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 50 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000027348	1 retrocopy	retro_btau_1647,
Homo sapiens	ENSG00000214788	2 retrocopies	retro_hsap_373, retro_hsap_4328,
Gorilla gorilla	ENSGGOG00000016792	6 retrocopies	retro_ggor_1709, retro_ggor_2172, retro_ggor_3079, retro_ggor_3085, retro_ggor_3086, retro_ggor_383,
Nomascus leucogenys	ENSNLEG00000013194	3 retrocopies	retro_nleu_2825, retro_nleu_2997, retro_nleu_3033,
Pongo abelii	ENSPPYG00000003223	20 retrocopies	retro_pabe_1419, retro_pabe_1525, retro_pabe_1707, retro_pabe_1713, retro_pabe_1716, retro_pabe_1720, retro_pabe_1745, retro_pabe_1749, retro_pabe_1761, retro_pabe_2101, retro_pabe_3226, retro_pabe_3227, retro_pabe_3229, retro_pabe_331, retro_pabe_3530, retro_pabe_3539, retro_pabe_3546, retro_pabe_3561, retro_pabe_3580, retro_pabe_3585,
Pan troglodytes	ENSPTRG00000034506	18 retrocopies	retro_ptro_1635 , retro_ptro_2588, retro_ptro_2591, retro_ptro_2593, retro_ptro_292, retro_ptro_3066, retro_ptro_3081, retro_ptro_3082, retro_ptro_3084, retro_ptro_3085, retro_ptro_3087, retro_ptro_3088, retro_ptro_3284, retro_ptro_3289, retro_ptro_3293, retro_ptro_3300, retro_ptro_3305, retro_ptro_3309,