RetrogeneDB ID: retro_ogar_356

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873520.1:52850112..52850683(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMADHC
• Ensembl ID: ENSOGAG00000034385
• Aliases: None
• Description: methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria [Source:HGNC Symbol;Acc:25221]

Sequence

>retro_ogar_356
GTGCTTTGTAACAGAGCCAGACTGATTTCCTGTCTTCACGATTTTGCTCTTTAGTTAACAGGGTTGTCAGTCTCAGAGCC
CTTTCAGCTGCAGGATCATCGGGTTCTGGTGAGTCTGAGGTGGCCGCTGCATCCCTAGATACCTGATCCTGAACCGTGTG
GCCTGATGAAACTGTGGGACCATTAGGACCTCAAGATCGGAGATGCCGGTTTCCTGGGAACATAGGTTTTGATTTTCACC
TCAGTGGCACCGCTTCACAGAAGAAAAGCCTGGTTCATAAAACTGCCTGTTGTCTGGCAGAACTTTTGTCAAGCTAAAGA
CATGATTTGTGATGACACAATATGTAAACGAATTTCAGAGTAAAGATGCACCTGTCGAACAAGAAATTAACAGTGCAGAA
ACTGACCTTGAAAGTGCCAGAGGAGAGTGTGCAATTCAAATGTGGCCAGAATTGCTGCAAAGGGATTTGAAATCACTATT
TCCAAAAGTAGCAGATAGCAAACTAATGATTCCGAATGTAGCTTGGAACACTGAGAATGACTGGAGGGAAGAGTTGGAAA
CTGAAAGAGAA

Alignment

ORF - retro_ogar_356 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.53 %
• Parental protein coverage: 66.55 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  VFCNRARLVSYLPGF-CSLVKRVVSPKAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRF
          V.CNRARL.S.L..F.CSLV.RVVS..A.S.AGSSGS.ES.VA.A..D..S.TVWPDET.GP.GPQD.R.
Retrocopy VLCNRARLISCLHDF<CSLVNRVVSLRALSAAGSSGSGESEVAAASLDT*S*TVWPDETVGPLGPQDRRC

Parental  QLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHE-FVMAQYVNEFQGNVAPVEQEINSAETYF
          ..PGNIGFD.HL.GTASQKKSLVHKT....LAE.LSS.RH..FVM.QYVNEFQ...APVEQEINSAET..
Retrocopy RFPGNIGFDFHLSGTASQKKSLVHKT-ACCLAELLSS*RHD<FVMTQYVNEFQSKDAPVEQEINSAETDL

Parental  ESARVECAIQTCPELLRRDFESLFPEVVNNKLMILTVTQKTKNDMTVWSEEVETERE
          ESAR.ECAIQ..PELL.RD..SLFP.V...KLMI..V...T.ND...W.EE.ETERE
Retrocopy ESARGECAIQMWPELLQRDLKSLFPKVADSKLMIPNVAWNTEND---WREELETERE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_356 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000003086	2 retrocopies	retro_cjac_4082, retro_cjac_4101,
Cavia porcellus	ENSCPOG00000007690	1 retrocopy	retro_cpor_30,
Homo sapiens	ENSG00000168288	2 retrocopies	retro_hsap_4716, retro_hsap_865,
Gorilla gorilla	ENSGGOG00000027348	1 retrocopy	retro_ggor_704,
Macaca mulatta	ENSMMUG00000005633	1 retrocopy	retro_mmul_1058,
Monodelphis domestica	ENSMODG00000003566	2 retrocopies	retro_mdom_1749, retro_mdom_620,
Mustela putorius furo	ENSMPUG00000000323	1 retrocopy	retro_mputfur_1253,
Nomascus leucogenys	ENSNLEG00000010795	2 retrocopies	retro_nleu_1988, retro_nleu_426,
Otolemur garnettii	ENSOGAG00000034385	4 retrocopies	retro_ogar_3266, retro_ogar_356 , retro_ogar_688, retro_ogar_813,
Pan troglodytes	ENSPTRG00000012525	1 retrocopy	retro_ptro_599,
Ictidomys tridecemlineatus	ENSSTOG00000021576	1 retrocopy	retro_itri_1809,
Tarsius syrichta	ENSTSYG00000009075	1 retrocopy	retro_tsyr_1690,