RetrogeneDB ID: retro_ogar_2201

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873601.1:4487790..4489506(+)
• Located in intron of: ENSOGAG00000030264

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ANXA6
• Ensembl ID: ENSOGAG00000011321
• Aliases: None
• Description: annexin A6 [Source:HGNC Symbol;Acc:544]

Sequence

>retro_ogar_2201
ATGGCCAAACCAGCACAGGGTGCCAAGTACCAGGATTTCATTCATGACTTCCCAAACTTCGACCTCAGGCAGGATGCTGA
GGCTCTGTACACCATCATGAAGGGCTTAGGCAGTGACAAGGAGGCCATACTGGAGCCAATCACCTCCCGGAGCAACAATC
AGAGGCAGGAGATCTGCCAGAGCTACAAGTCCCTCTATGGTAAGGACCTCATTACTGACTTGAAGTATGAGCTGATGGGG
AAGTTTGAATGGCTGATTGTGGGCCTAATGTAACCACTTGCCTATTTTGATGCCAAGGAGATTAAAGATGCCATCTCAGG
CATTGGTACAGATGAGAAATGCCTCATTGAGATCTTGGCTTCCCGGACCAATGAGCAGATTCACCAGCTGGTAGCAGCAT
ACAAAGATGTGTATGAGCAGGACCTGGAGTCTGATGTCATTGGAGACACCTCTGGCCACTTCTAGAAGATGCTTGTGGTC
CTGCTCCAGGGAACCAGGGAGGAGGACGATGTAGTGAGTAAGGACCAGGTACAACAGGATGTCCAAGACCTGTATGAGGC
AGGGGAACTGAAATGGGGGACAGATGAAGCCCAGTTCATTTACATCTTGGGAAATCGCAGCAAATAGCATCTTCGGTTGG
TGTTTGATGAGTACCTGAAGATGACAGGAAAACCGATTAAAGCCAGCATCCGAGACGAGCTGTCCAGGGACTTTGAGAAG
CTAATGCTGGCTGTGGTGAAATGTATCCAGAGCACTTCAGAGTATTTTACTGAAAGGCTCTTCAAGGCCATGAAGGTCCT
GGGGACTCGGGACAACACCCTGATCTGCATCATGGTCTTCCAGAGCAAGCTGGACATGCTTGACATCCATGAGGTCTTCT
GGACCAAGTATGAGAAGTCTCTCTACAGCAGGATCAAGAATGATACCTCTGGTGAGTACAAGAAGGCTCTGCTGAAGTTG
TGTGGTGGAAATGATGATGCTGCTGGCCAGTTCTTCCTGGAGGCAGCTCAGGTGGCCTATCAGATGTGGGAACTTAGTGC
AGTGTTGTGAGTAAAGCTGAAGGGAACTGTGCGCCCAGCCAATGACTTCAACCCTGATGCAGATGCCAAAGTGCTGCAGA
AAGCCATGAAGGGACTTGGAACTGATGAAGTTACCATCATTGATATCATCACACACTGCAGCAATGCCCAGTGGCAGCAG
ATCCGGTAGACCTTCAAGTCTCACTTTGACCGGGACTTAATGGCTGACCTGAAGTCTGAGCTCTCTGGAGATCTGGCGAG
GCTGATTCTGGGGCTCATGATGTCACCAGCCCACTATGATGCCAAGCAGTGGAAGAAGGACATGGAGGGAGCTGGCACAG
ATGAAAAGGCTCTTATCCAAATCCTGGCCACTCGGACCAATGTCAAAATCCAGGCCATCAATGAAGCCTATAAAGAGGAC
TATCACAAGTCCCTGGAGGATACCTTGAGCTCAGACACATCTGTCCACTTCAGGCGAATCCTCATTTCTCTAGTCACGGG
GAACTGTGAAGAGGGAGGAGAAAACCGGGACCAGGCCCGGGAAGATGCCCAGGTGCCTGCTGAGATCTTGGAGATAGCCG
ACATGCCTAGTAGAGACAAAACTTCCTTAGAGACGCGTTTCATGACGGTTCTGTGCACCCGCAGCTACCTTCACCTCCAG
AGAGTTTTCCAGGAGTTCATCAAGATGACCAATTAT

Alignment

ORF - retro_ogar_2201 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.16 %
• Parental protein coverage: 84.99 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAKPAQGAKYRGSIHDFPNFDPSQDAEALYTAMKGLGSDKEAILELITSRSNSQRQEICQNYKSLYGKDL
          MAKPAQGAKY...IHDFPNFD..QDAEALYT.MKGLGSDKEAILE.ITSRSN.QRQEICQ.YKSLYGKDL
Retrocopy MAKPAQGAKYQDFIHDFPNFDLRQDAEALYTIMKGLGSDKEAILEPITSRSNNQRQEICQSYKSLYGKDL

Parental  IADLKYELMGKFERLIVGLMRPLAYFDAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLVAAYKDAYER
          I.DLKYELMGKFE.LIVGLM.PLAYFDAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLVAAYKD.YE.
Retrocopy ITDLKYELMGKFEWLIVGLM*PLAYFDAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLVAAYKDVYEQ

Parental  DLESDVIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQH
          DLESDVIGDTSGHF.KMLVVLLQGTREEDDVVS.D.VQQDVQDLYEAGELKWGTDEAQFIYILGNRSK.H
Retrocopy DLESDVIGDTSGHF*KMLVVLLQGTREEDDVVSKDQVQQDVQDLYEAGELKWGTDEAQFIYILGNRSK*H

Parental  LRLVFDEYLKKTGKPIEASIRGELSGDFEKLMLAVVKCIRSTSEYFAERLFKAMKGLGTRDNTLIRIMVS
          LRLVFDEYLK.TGKPI.ASIR.ELS.DFEKLMLAVVKCI.STSEYF.ERLFKAMK.LGTRDNTLI.IMV.
Retrocopy LRLVFDEYLKMTGKPIKASIRDELSRDFEKLMLAVVKCIQSTSEYFTERLFKAMKVLGTRDNTLICIMVF

Parental  RSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVSR
          .S.LDMLDI.E.F.TKYEKSLYS.IKNDTSGEYKKALLKLCGG.DDAAGQFF.EAAQVAYQMWELSAV..
Retrocopy QSKLDMLDIHEVFWTKYEKSLYSRIKNDTSGEYKKALLKLCGGNDDAAGQFFLEAAQVAYQMWELSAVL*

Parental  VELKGTVRPANDFNPDADAKALRKAMKGLGTDEGTIIDIITRRSNAQRQQIRQTFKSHFGRDLMADLKSE
          V.LKGTVRPANDFNPDADAK.L.KAMKGLGTDE.TIIDIIT..SNAQ.QQIR.TFKSHF.RDLMADLKSE
Retrocopy VKLKGTVRPANDFNPDADAKVLQKAMKGLGTDEVTIIDIITHCSNAQWQQIR*TFKSHFDRDLMADLKSE

Parental  LSGDLARLILGLMMSPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALS
          LSGDLARLILGLMMSPAHYDAKQ.KK.MEGAGTDEKALI.ILATRTN..I.AINEAYKEDYHKSLED.LS
Retrocopy LSGDLARLILGLMMSPAHYDAKQWKKDMEGAGTDEKALIQILATRTNVKIQAINEAYKEDYHKSLEDTLS

Parental  SDTSGHFRRILISLATGNREEGGEDRDQAREDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLR
          SDTS.HFRRILISL.TGN.EEGGE.RDQAREDAQV.AEILEIAD.PS.DKTSLETRFMTVLCTRSY.HL.
Retrocopy SDTSVHFRRILISLVTGNCEEGGENRDQAREDAQVPAEILEIADMPSRDKTSLETRFMTVLCTRSYLHLQ

Parental  RVFQEFIKMTNY
          RVFQEFIKMTNY
Retrocopy RVFQEFIKMTNY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2201 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Otolemur garnettii	ENSOGAG00000003878	1 retrocopy	retro_ogar_2257,
Otolemur garnettii	ENSOGAG00000009311	1 retrocopy	retro_ogar_108,
Otolemur garnettii	ENSOGAG00000009952	1 retrocopy	retro_ogar_3510,
Otolemur garnettii	ENSOGAG00000011321	1 retrocopy	retro_ogar_2201 ,