RetrogeneDB ID: retro_mmul_2367

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 8:110536185..110536921(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: AURKB
• Ensembl ID: ENSMMUG00000002997
• Aliases: None
• Description: None

Sequence

>retro_mmul_2367
ACCAAAGCTGCGCTTGAGCTCCTGAGCTGCGCAGACGCACAGCCCGCAGCAACCCCTGCCATGAGGTGGTGGAGAACAGC
TGTGGGACAAGCAGCATCTTAACGCGGCCCTTCACGGTCGACGACCTTGAGACTGGGCGTCCCCCGGGCAAAGACAAGTT
TGCACATGTGTACTTAGCTCCAAAGAAGAAAAGCCATTTCATCGTGGCCCTCAAGGCCTTCAAGTCTCAGATAGAGAAGG
AGGGCGTGGGGAGCACCAGCTGCACAGGCAGATAGAAATCCAGGCCCCCGTTCAGCATCCCAAATATACTGAGTTGCTAC
AACTACTTTTATGACCTGAGAAAAATCTACTGAATTATAGAGTACGCCCCCGTCACCTCTACCCGCGAGGAGTTGTACCA
GGAGCTGCGGAAGAGCCGCACCTTTGACAGGAAACGAACAGCCAGCATCATGGGGGAGGTGGCAGGTGCGCTGATGTACT
GCCACGGGAAGAAGGTGACTCCCAGACATAAAGCCAGAGAATCTGCTCTCAGGGCTTGAGAGCGAGCTGAAAGTTGCCGA
CTTCCGCTGCCTTGTGCACGCCCCCTCACTGAGGAGGAAGACAAATGTGTGGCGCCCTGGACTACCTGTTCCCGGAGACA
ATTGAGGGGCGCGCGCACACAGAGAAGGTGGATCTGTGGTACACCGGAGTACTCGGCTATGAGCCGCTGGTGGGGAACCC
CACACACAATGAGGCC

Alignment

ORF - retro_mmul_2367 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 62.7 %
• Parental protein coverage: 70.35 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 6

Retrocopy - Parental Gene Alignment:

Parental  TPSALVLMSRSNVQPTAAPGQK-VVENSSGTPNILMRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIV
          T..AL.L.S....QP.A.P....VVENS.GT..IL.R.FT.DD.E.GRP.GK.KF..VYLA..KKSHFIV
Retrocopy TKAALELLSCADAQPAATPAMR<VVENSCGTSSILTRPFTVDDLETGRPPGKDKFAHVYLAPKKKSHFIV

Parental  ALKV-LFKSQIEKEGVEHQLRREIEIQAHLHHP-NILRLYNYFYDRRRIYLILEYAP----RGELYKELQ
          ALK..L..S..E....EHQL.R.IEIQA...HP.NIL..YNYFYD.R.IY.I.EYAP....R.ELY.EL.
Retrocopy ALKA<LQVSDREGGRGEHQLHRQIEIQAPVQHP>NILSCYNYFYDLRKIY*IIEYAPVTSTREELYQELR

Parental  KSRTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL-LGLK-GELKIADFGWSVHAPSLRRKT-MC
          KSRTFD..RTA.IM.E.A.ALMYCHGKKV..R....E..L..GL...ELK.ADF...VHAPSLRRKT.MC
Retrocopy KSRTFDRKRTASIMGEVAGALMYCHGKKVTPRHKARESAL<QGLR<SELKVADFRCLVHAPSLRRKT>MC

Parental  GTLDYLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESA
          G.LDYL.PE.IEGR.H.EKVDLW..GVL.YE.LVGNP....A
Retrocopy GALDYLFPETIEGRAHTEKVDLWYTGVLGYEPLVGNPTHNEA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.22 RPM
SRP007412_brain_prefrontal_cortex	0.16 RPM	0.08 RPM
SRP007412_cerebellum	0.00 RPM	0.26 RPM
SRP007412_heart	0.00 RPM	0.41 RPM
SRP007412_kidney	0.00 RPM	1.06 RPM
SRP007412_liver	0.00 RPM	1.70 RPM
SRP007412_testis	0.00 RPM	3.73 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2367 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2367 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2367 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Microcebus murinus	ENSMICG00000013775	1 retrocopy	retro_mmur_567,
Myotis lucifugus	ENSMLUG00000003633	2 retrocopies	retro_mluc_764, retro_mluc_798,
Macaca mulatta	ENSMMUG00000000070	1 retrocopy	retro_mmul_431,
Macaca mulatta	ENSMMUG00000002997	1 retrocopy	retro_mmul_2367 ,
Pteropus vampyrus	ENSPVAG00000016378	1 retrocopy	retro_pvam_1045,
Tursiops truncatus	ENSTTRG00000010318	1 retrocopy	retro_ttru_542,