RetrogeneDB ID: retro_mmul_133

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:74365381..74366023(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000021206
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: MOSPD1
• Ensembl ID: ENSMMUG00000022505
• Aliases: None
• Description: motile sperm domain-containing protein 1 [Source:RefSeq peptide;Acc:NP_001248549]

Sequence

>retro_mmul_133
ATGCATCAACAAAAAAGACAGCCAGAGTTAGTGGAAGGAAATCTTTCTGTTTTCGTGTTCCCCATGGAGCTCATATTTTA
TGCAGATGATCAGTCAACACATAAGCAAGTGTTGACACTGTACAATCCCTATGAGTTTGCCTTAAAGTTCAAAGTTTTGT
GTACTACCCCAAATAAGTATGTTGTCGTTGATGCTGCAGATGCAGTAAAGCCTCAGTGTTGTGTGGATATTGTGATTCGT
CATAGAGATGTTCGATCCTGTCACTATGGTGTAATAGACAAATTTCGTCTTCAAGTTTCTGAGCAAAGCCAGAGGAAGGC
TTTGGGAAGAAAAGAGGTTGTTGCTACTCTTCTCCCATCAGCAAAAGAACAACAAAAGGAAGAAGAGGAAAAAAGAATAA
AGGAACATTTAACTGAAAGTTTATTTTTTGAGCAGTCATTTCAACCAGAAAACAGAGCTGTCTCCTCAGGACCTAGTTTA
CTAACTGTCTTCCTGGGAGTGGTGTGCATTGCAGCCCTGATGCTGCCTACAATGGGGGATGTGGAATCGCTGGTGCCTCT
CTACCTCCACTTAAGTGTGAATCAAAAATTAGTGGCTGCTTATATCGTAGGTCTTATCACAATGGCCATACTTAGAACAT
GA

Alignment

ORF - retro_mmul_133 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 97.2 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVK
          MHQQKRQPELVEGNL.VFVFP.ELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAA.AVK
Retrocopy MHQQKRQPELVEGNLSVFVFPMELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAADAVK

Parental  PQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRIKEHLTES
          PQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRIKEHLTES
Retrocopy PQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRIKEHLTES

Parental  LFFEQSFQPGKNRAVSSGPSLLTVFLGVVCIAALMLPTMGDVESLVPLYLHLSVNQKLVAAYILGLITMA
          LFFEQSFQP..NRAVSSGPSLLTVFLGVVCIAALMLPTMGDVESLVPLYLHLSVNQKLVAAYI.GLITMA
Retrocopy LFFEQSFQP-ENRAVSSGPSLLTVFLGVVCIAALMLPTMGDVESLVPLYLHLSVNQKLVAAYIVGLITMA

Parental  ILRT
          ILRT
Retrocopy ILRT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.22 RPM	1.12 RPM
SRP007412_brain_prefrontal_cortex	0.08 RPM	1.98 RPM
SRP007412_cerebellum	0.13 RPM	1.23 RPM
SRP007412_heart	0.00 RPM	1.24 RPM
SRP007412_kidney	0.12 RPM	1.17 RPM
SRP007412_liver	0.00 RPM	0.28 RPM
SRP007412_testis	0.00 RPM	0.98 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_133 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_133 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_133 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001304	1 retrocopy	retro_amel_683,
Choloepus hoffmanni	ENSCHOG00000007386	5 retrocopies	retro_chof_1202, retro_chof_1623, retro_chof_201, retro_chof_2295, retro_chof_675,
Dasypus novemcinctus	ENSDNOG00000013117	4 retrocopies	retro_dnov_1825, retro_dnov_2650, retro_dnov_2660, retro_dnov_926,
Macaca mulatta	ENSMMUG00000022505	1 retrocopy	retro_mmul_133 ,
Monodelphis domestica	ENSMODG00000015178	1 retrocopy	retro_mdom_159,
Mus musculus	ENSMUSG00000023074	1 retrocopy	retro_mmus_291,
Otolemur garnettii	ENSOGAG00000005739	2 retrocopies	retro_ogar_2508, retro_ogar_528,
Sarcophilus harrisii	ENSSHAG00000011544	1 retrocopy	retro_shar_21,
Sus scrofa	ENSSSCG00000012686	1 retrocopy	retro_sscr_690,
Ictidomys tridecemlineatus	ENSSTOG00000008152	1 retrocopy	retro_itri_1303,
Tarsius syrichta	ENSTSYG00000006102	1 retrocopy	retro_tsyr_1785,