RetrogeneDB ID: retro_ggor_269

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:99045872..99046444(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENSG00000085365
• Ensembl ID: ENSGGOG00000015191
• Aliases: None
• Description: None

Sequence

>retro_ggor_269
CCTCCACCAGGCAGTGTGAGGATGCCTAATGTACCCAATACACAACCAGCAATAATGAAACCAACAGAGAAACATCCAGT
TTATACACCGATTGCAAAAAAACATGCATTGGCCCAAGCTGAACTTCTTAAACACCAGGAAGAAGTAGAAAGAAAAGATG
CAGAATTAGTCATCGGGAATGAGAAATGCAAAACCTCACTCAACATGGTAGAAAAAATAATTGGCCACTTCTTCTTAGCA
ATTTTCCTATAGAACCTTGTTTCTATCAGGATTTTTCTGTTGACATTCCTATAGAATTCCAAAAGACAGTAAAGCTTATA
TACTACTTGTGGATGTTCCATGCTGTAACACTGTTTCTAAATATCTTCAGATGCTTGTCTTGGTTTTGTGTTGATTTTGC
AAGAGTGGTTGATTTTAGTTTGAGTATCCTGTGGTTCTTGCTTTTTACTCCTTGTTCATTTGTCTGTTGGTACAGACCAC
TTTATGGAGCTTTCAGGAGTGACAGTTCATTCAGACTCTTTGTATTCTTCTTCGTCTATATTTGTTAGTTTGCTGTACAT
GCATTCCAGGCA

Alignment

ORF - retro_ggor_269 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.42 %
• Parental protein coverage: 56.51 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  PPPGSVKMPNVPNTQPAIMKPTEEHPAYTQIAKEHALAQAELLKRQEELERKAAEL-DRREREMQNLSQH
          PPPGSV.MPNVPNTQPAIMKPTE.HP.YT.IAK.HALAQAELLK.QEE.ERK.AEL...RE.EMQNL.QH
Retrocopy PPPGSVRMPNVPNTQPAIMKPTEKHPVYTPIAKKHALAQAELLKHQEEVERKDAEL<SHRE*EMQNLTQH

Parental  GRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDF
          GRKNNWP.L.SNFP..PCFYQDFSVDIP.EFQKTVKL.YYLWMFHAVTLFLNIF.CL.WFCVD.AR.VDF
Retrocopy GRKNNWPLLLSNFPIEPCFYQDFSVDIPIEFQKTVKLIYYLWMFHAVTLFLNIFRCLSWFCVDFARVVDF

Parental  GLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQA
          .LSILWFLLFTPCSFVCWYRPLYGAFRSDSSFR.FVFFFVYIC.FAVH..QA
Retrocopy SLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRLFVFFFVYIC*FAVHAFQA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	61.24 RPM
SRP007412_cerebellum	0.00 RPM	50.43 RPM
SRP007412_heart	0.00 RPM	3.53 RPM
SRP007412_kidney	0.00 RPM	26.50 RPM
SRP007412_liver	0.00 RPM	14.27 RPM
SRP007412_testis	0.00 RPM	30.98 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_269 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_269 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_189
Macaca mulatta	retro_mmul_396

---

Parental genes homology:

Parental genes homology involve 8 parental genes, and 8 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000032395	1 retrocopy	retro_cfam_227,
Cavia porcellus	ENSCPOG00000008868	1 retrocopy	retro_cpor_174,
Homo sapiens	ENSG00000085365	1 retrocopy	retro_hsap_189,
Gorilla gorilla	ENSGGOG00000015191	1 retrocopy	retro_ggor_269 ,
Macaca mulatta	ENSMMUG00000016398	1 retrocopy	retro_mmul_396,
Monodelphis domestica	ENSMODG00000019731	1 retrocopy	retro_mdom_964,
Nomascus leucogenys	ENSNLEG00000012775	1 retrocopy	retro_nleu_1000,
Tarsius syrichta	ENSTSYG00000014113	1 retrocopy	retro_tsyr_1676,