RetrogeneDB ID: retro_ggor_2465

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:116551103..116551679(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024360
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: RPS5
• Ensembl ID: ENSGGOG00000004258
• Aliases: None
• Description: None

Sequence

>retro_ggor_2465
ATGACCGCGTGGGAGACAGCAGCACCAGCAGTGGCAGAGACCCCAGACATCAAGCTCTTTGGAAAGTGGAGCACTGATGA
TGTGCACATCAGTGACATTTCCCTGCAGGATTACATTGCAGTGAAGGAGAAATATGCCAAGTACCTACCTCACAGTGCAG
GGTGGTATGCCGCCAAATGCTTCCGCAAAGCTCAGTGTCCCATTGTGGAACGCCTTACTAACTCCATGATGATGCACGGC
TGCAACAACGGCAAGAAGCTCATGACTGTGTGCATCGTCAAGCATGCCTTTGAGGTCATACACCTGCTCACAGGCGAGAA
CCCTCTGCAGGTCCTGGTGAACGCCATCATCAACAGTGGTCCTCGGGAGGACTCCACACGCATTGGGTGCGCCAGGACTG
TGAGACGACAGGCTGTGGACGTGTCCCCACTTCGCCGTGTGAATCAGGCCATGTGGCTGCTGTGCACAGGTGCTCGTGAG
GCTGCCTTCCGGAACATTAAGACCATTGCTGAGTGCCTGGCAGAGGAGCTCATCAATGCTGCCAAGGGCTCCTCCAACTC
CTATGCCATTAAGAAG

Alignment

ORF - retro_ggor_2465 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.75 %
• Parental protein coverage: 94.12 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MTEWETAAPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVE
          MT.WETAAPAVAETPDIKLFGKWSTDDV.I.DISLQDYIAVKEKYAKYLPHSAG.YAAK.FRKAQCPIVE
Retrocopy MTAWETAAPAVAETPDIKLFGKWSTDDVHISDISLQDYIAVKEKYAKYLPHSAGWYAAKCFRKAQCPIVE

Parental  RLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVD
          RLTNSMMMHG.NNGKKLMTV.IVKHAFE.IHLLTGENPLQVLVNAIINSGPREDSTRIG.A.TVRRQAVD
Retrocopy RLTNSMMMHGCNNGKKLMTVCIVKHAFEVIHLLTGENPLQVLVNAIINSGPREDSTRIGCARTVRRQAVD

Parental  VSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKK
          VSPLRRVNQA.WLLCTGAREAAFRNIKTIAECLA.ELINAAKGSSNSYAIKK
Retrocopy VSPLRRVNQAMWLLCTGAREAAFRNIKTIAECLAEELINAAKGSSNSYAIKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.14 RPM	93.89 RPM
SRP007412_cerebellum	0.47 RPM	103.70 RPM
SRP007412_heart	0.25 RPM	97.75 RPM
SRP007412_kidney	0.94 RPM	190.54 RPM
SRP007412_liver	0.74 RPM	313.82 RPM
SRP007412_testis	2.28 RPM	103.81 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2465 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2465 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3649
Pongo abelii	retro_pabe_2996

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000002366	1 retrocopy	retro_cfam_1355,
Callithrix jacchus	ENSCJAG00000000304	6 retrocopies	retro_cjac_1463, retro_cjac_2049, retro_cjac_2050, retro_cjac_2508, retro_cjac_4105, retro_cjac_599,
Echinops telfairi	ENSETEG00000013543	1 retrocopy	retro_etel_912,
Homo sapiens	ENSG00000083845	5 retrocopies	retro_hsap_2524, retro_hsap_2526, retro_hsap_3649, retro_hsap_3976, retro_hsap_4224,
Gorilla gorilla	ENSGGOG00000004258	4 retrocopies	retro_ggor_1577, retro_ggor_2465 , retro_ggor_2828, retro_ggor_2942,
Macropus eugenii	ENSMEUG00000015400	3 retrocopies	retro_meug_1075, retro_meug_1792, retro_meug_347,
Myotis lucifugus	ENSMLUG00000012641	1 retrocopy	retro_mluc_2266,
Macaca mulatta	ENSMMUG00000008729	3 retrocopies	retro_mmul_1595, retro_mmul_2525, retro_mmul_77,
Mustela putorius furo	ENSMPUG00000008308	1 retrocopy	retro_mputfur_1316,
Ornithorhynchus anatinus	ENSOANG00000011921	1 retrocopy	retro_oana_83,
Otolemur garnettii	ENSOGAG00000013088	2 retrocopies	retro_ogar_1711, retro_ogar_3461,
Procavia capensis	ENSPCAG00000011034	2 retrocopies	retro_pcap_168, retro_pcap_58,
Pongo abelii	ENSPPYG00000010500	7 retrocopies	retro_pabe_1857, retro_pabe_1858, retro_pabe_2996, retro_pabe_3270, retro_pabe_3413, retro_pabe_3683, retro_pabe_375,
Pan troglodytes	ENSPTRG00000011591	6 retrocopies	retro_ptro_1469, retro_ptro_1471, retro_ptro_2474, retro_ptro_2700, retro_ptro_2868, retro_ptro_3152,
Ictidomys tridecemlineatus	ENSSTOG00000005935	1 retrocopy	retro_itri_1742,
Tupaia belangeri	ENSTBEG00000016955	2 retrocopies	retro_tbel_1127, retro_tbel_1169,
Tarsius syrichta	ENSTSYG00000000076	2 retrocopies	retro_tsyr_1258, retro_tsyr_1981,
Tursiops truncatus	ENSTTRG00000001991	1 retrocopy	retro_ttru_106,