RetrogeneDB ID: retro_ggor_1233

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 16:37160022..37161315(+)
• Located in intron of: ENSGGOG00000003010

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000013695
• Aliases: None
• Description: None

Sequence

>retro_ggor_1233
GCAAAAAAGAAGAATAAGAAGGGGAAGACTCTCTCCCTAACAGACTCTCTGGCTGAGGATGGGGGGACTGGTGGAGGAAG
CATCTATGTTTCCAAACCAGTCAGCTGGGCTCATGAAACAGATGACCTGGAAGGAGATATTTCAACAACTTGGAACAGTA
ATGATGAAGATGTGTATAGGGCACCTCCAATTGACCGTTCCATCCTTCCCACTGCTCCAGGGGCTGCTTGGGAACCCAAT
ATCGACTGGAGCCATCTTCCCAAATTGTCACCCTACATTGCTTTTCTAGGGAACCTACCCTATGATGTGACAGAAGAGTG
CATTAAGGAATTCTTTAGAGGACTAAGTATCAGTGCAGTGCTTTTACCACGTGAACCCAGCAATCCAGAGAAGTTGAAAG
GTTTTGGTTATGCTGAATTTGAGGACCTGGATTCCCTGCTCAGTGCCCTGAGTCTCAATGAAGAGTCTCTAGGTAACAGG
AGAATTTGAGTGGACGTTGCTGATCAAGCACAGGATAAAGACAGGAATGATCGTTCTTCTGGCTGTGATAGAAATTGCGA
TTATGACAAAACAGATACAGACTGAAGGGCTCGTCCTGCCACAGACAGCTTTGATGACTACTCACCTAGAAGAGGTGATG
ATAGCTTTGGAGACAAGTATCGAGATCATTATGATTCAGATTGGTATTGTGATGAGTATTGGGATGGCCCACGCACGGAT
ATGGATTGATATGGCGACTGGGATTGCTATGATGACCAAGGCAGCAGAGACTATGATAGAGGCTATGATTCCCAGATAGG
CAATGGCAGAAAAGCATTTGGCAGTGGGTACCACAGGGATGATGACTACAGAGGAGGTGGGGACTGTGATGAAGACTGAT
CCAACAGACGGGATGATCGGTCATAGAGCTCCAGAGATGATTACTCTTGGGATGATTATAGGCGTGATGATAGAGGTCCC
CCACAAAGACCCAAACTGAATCTAAAGCCTCAGAGTACTCCTAAGGAAGATGATTCCTCTGCTAGTACCTCCCAGTCCAG
TCAAGCTGCTTCTATCTTTGGAGGGACAAAGCCCATTGACACAGTTGCTAGAGAAAGAGAAGTAGAACAGCTACAGAAGG
AACAAGAGAAGTTGCAGCATCAGCTGGATGAGCCAAAACTAGAACGATGGCCTCGGGAGAGACACCCAAGCTGGCAAAGT
GAAGAAACTCAGGAACAGGAACGGTTGAGGACAGGAAGTGAGTCATCACAGACCGGGGCCTCTGCCACATCCGGCAGAAA
TGCACGAGGGAGA

Alignment

ORF - retro_ggor_1233 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 84.17 %
• Parental protein coverage: 71.36 %
• Number of stop codons detected: 5
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  AKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILP
          AKKKNKKGKT.SLTD.LAEDGGTGGGS.YVSKPVSWA.ETDDLEGD.STTW.SND.DVYRAPPIDRSILP
Retrocopy AKKKNKKGKTLSLTDSLAEDGGTGGGSIYVSKPVSWAHETDDLEGDISTTWNSNDEDVYRAPPIDRSILP

Parental  TAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEF
          TAP.AA.EPNID.S.LPK..PY.AFLGNLPYDVTEE.IKEFFRGL.ISAV.LPREPSNPE.LKGFGYAEF
Retrocopy TAPGAAWEPNIDWSHLPKLSPYIAFLGNLPYDVTEECIKEFFRGLSISAVLLPREPSNPEKLKGFGYAEF

Parental  EDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDTFDDYPPR
          EDLDSLLSALSLNEESLGNRRI.VDVADQAQDKDR.DRS.G.DRN.D.DKTDTD.RARPATD.FDDY.PR
Retrocopy EDLDSLLSALSLNEESLGNRRI*VDVADQAQDKDRNDRSSGCDRNCDYDKTDTD*RARPATDSFDDYSPR

Parental  RGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSG
          RGDDSFGDKYRD.YDSD.Y.D.Y.DG....PR.DMD.YG..D.YDD.GSRDYDRGYDS.IG.GR.AFGSG
Retrocopy RGDDSFGDKYRDHYDSDWYCDEYWDG----PRTDMD*YGDWDCYDDQGSRDYDRGYDSQIGNGRKAFGSG

Parental  YRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQS
          Y.RDDDYRGGGD..ED...RRDDRS.SSRDDYS.DDYRRDDRGPPQRPKLNLKP.STPKEDDSSASTSQS
Retrocopy YHRDDDYRGGGDCDED*SNRRDDRS*SSRDDYSWDDYRRDDRGPPQRPKLNLKPQSTPKEDDSSASTSQS

Parental  TRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSES
          ..AASIFGG.KP.DT.AREREVE..LQKEQEKLQ.QLDEPKLER.PRERHPSW.SEETQE.ER.RTGSES
Retrocopy SQAASIFGGTKPIDTVAREREVEQ-LQKEQEKLQHQLDEPKLERWPRERHPSWQSEETQEQERLRTGSES

Parental  SQTGTSTTSGRNARRR
          SQTG.S.TSGRNAR.R
Retrocopy SQTGASATSGRNARGR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	105.16 RPM
SRP007412_cerebellum	0.00 RPM	94.32 RPM
SRP007412_heart	0.00 RPM	51.50 RPM
SRP007412_kidney	0.00 RPM	153.86 RPM
SRP007412_liver	0.00 RPM	78.11 RPM
SRP007412_testis	0.00 RPM	171.98 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1233 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1233 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012023	2 retrocopies	retro_amel_1107, retro_amel_559,
Canis familiaris	ENSCAFG00000007117	2 retrocopies	retro_cfam_1447, retro_cfam_936,
Choloepus hoffmanni	ENSCHOG00000001608	2 retrocopies	retro_chof_1310, retro_chof_366,
Callithrix jacchus	ENSCJAG00000018176	2 retrocopies	retro_cjac_1717, retro_cjac_2001,
Cavia porcellus	ENSCPOG00000005595	3 retrocopies	retro_cpor_278, retro_cpor_752, retro_cpor_937,
Homo sapiens	ENSG00000063046	7 retrocopies	retro_hsap_1686, retro_hsap_2639, retro_hsap_2698, retro_hsap_3767, retro_hsap_4196, retro_hsap_4848, retro_hsap_4891,
Gorilla gorilla	ENSGGOG00000005284	1 retrocopy	retro_ggor_1598,
Gorilla gorilla	ENSGGOG00000013695	5 retrocopies	retro_ggor_1233 , retro_ggor_1263, retro_ggor_1882, retro_ggor_1883, retro_ggor_3024,
Loxodonta africana	ENSLAFG00000009534	1 retrocopy	retro_lafr_294,
Macropus eugenii	ENSMEUG00000012341	2 retrocopies	retro_meug_1054, retro_meug_585,
Macaca mulatta	ENSMMUG00000001062	5 retrocopies	retro_mmul_1428, retro_mmul_2384, retro_mmul_2589, retro_mmul_731, retro_mmul_783,
Mus musculus	ENSMUSG00000058655	1 retrocopy	retro_mmus_3686,
Nomascus leucogenys	ENSNLEG00000017727	3 retrocopies	retro_nleu_2371, retro_nleu_2601, retro_nleu_721,
Pongo abelii	ENSPPYG00000025848	7 retrocopies	retro_pabe_1388, retro_pabe_1560, retro_pabe_2283, retro_pabe_260, retro_pabe_3532, retro_pabe_3768, retro_pabe_506,
Rattus norvegicus	ENSRNOG00000010103	2 retrocopies	retro_rnor_2467, retro_rnor_2972,
Ictidomys tridecemlineatus	ENSSTOG00000006800	1 retrocopy	retro_itri_604,
Tupaia belangeri	ENSTBEG00000005423	2 retrocopies	retro_tbel_2363, retro_tbel_4167,
Tarsius syrichta	ENSTSYG00000012880	1 retrocopy	retro_tsyr_452,