RetrogeneDB ID: retro_fcat_131

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: D2:51736641..51737886(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSFCAG00000028219
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: HNRNPH1
• Ensembl ID: ENSFCAG00000001204
• Aliases: None
• Description: heterogeneous nuclear ribonucleoprotein H1 (H) [Source:HGNC Symbol;Acc:5041]

Sequence

>retro_fcat_131
ATGATGCTGGGCCCCGAGGGAGGTGAAGGCTTTGTGGTCAAGCTCCGTGGCCTGCCCTGGTCCTGCTCTGTTGAGGATGT
GCAGAATTTCCTTTCTGACTGCACAATACATGATGGGGCTGCAGGCGTTCATTTCATCTACACTAGAGAAGGCAGGCAGA
GTGGTGAGGCTTTTGTTGAACTTGAATCAGAAGATGATGTAAAAATGGCCCTTAAAAAAGACAGGGAAAGCATGGGACAC
CGGTACATTGAGGTGTTCAAGTCCCACAGAACCGAGATGGATTGGGTGTTGAAGCACAGTGGTCCAAACAGTGCCGACAC
CGCCAATGATGGCTTCGTGCGGCTTCGAGGACTCCCATTTGGATGCACCAAGGAAGAAATTGTTCAGTTCTTCTCAGGGT
TGGAAATTGTGCCAAACGGGATCACATTGCCTGTGGACCCCGAGGGCAAGATTACAGGGGAAGCCTTTGTGCAGTTTGCC
TCACAGGAGTTAGCTGAGAAGGCCCTAGGGAAGCACAAGGAGAGAATAGGGCACAGGTATATTGAAGTGTTCAAGAGCAG
TCAGGAAGAAGTTAGGTCATACTCGGATCCCCCTCTGAAGTTCATGTCTGTACAGCGGCCAGGGCCCTATGACCGCCCTG
GCACGGCCAGGAGGTATATTGGCATTGTCAAGCAAGCGGGCCTGGAGAGGATGAGGTCTGGTGCTTATAGCGCAGGCTAT
GGGGGCTATGAGGAGTACAGCGGCCTCAGCGATGGCTACGGCTTCACCACTGATCTGTTTGGGAGAGACCTCAGTTACTG
TCTCTCAGGCATGTATGACCACAGATACGGAGACGGCGAGTTCACTGTCCAGAGTACCACTGGACACTGTGTCCACATGA
GAGGGCTACCATACAAAGCCACAGAGAACGACATTTACAACTTCTTCTCTCCACTCAACCCTGTGAGAGTCCATATTGAG
ATTGGCCCTGATGGAAGAGTGACGGGCGAAGCCGATGTTGAGTTCGCCACTCACGAAGAAGCTGTGGCAGCAATGTCCAA
AGACCGGGCCAACATGCAACACAGATACATAGAACTTTTCCTGAATTCCACAACTGGGGCCAGCAATGGGGCGTACAGCA
GCCAGATGATGCAAGGCATGGGGGTGTCGGCCCAGTCCACTTACAGTGGCCTCGAGAGCCAGTCTGTGAGTGGCTGTTAT
GGGGCTGGCTATGGAGGCCAGAACAGCATGGGTGGATATGACTAG

Alignment

ORF - retro_fcat_131 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75. %
• Parental protein coverage: 86.86 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLA
          MMLG.EGGEGFVVK.RGLPWSCS...VQ.F.SDC.I..GA.G..FIYTREGR.SGEAFVELESED.VK.A
Retrocopy MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELESEDDVKMA

Parental  LKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNG
          LKKDRE.MGHRY.EVFKS...EMDWVLKH.GPNS.DTANDGFVRLRGLPFGC.KEEIVQFFSGLEIVPNG
Retrocopy LKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADTANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNG

Parental  ITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPY
          ITLPVD..G..TGEAFVQFASQE.AEKAL.KHKERIGHRYIE.FKSS..EVR...DPP.K.M..QRPGPY
Retrocopy ITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPY

Parental  DRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGG
          DRPG..R.Y..I...AG.ERMR.GAY..GYGGY..Y.G..DGYGF..D.FGRDL.YC.SGM.DHRYGDG.
Retrocopy DRPGTARRYIGIVKQAGLERMRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDGE

Parental  STFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKA
          .T.QSTTGHCVHMRGLPY.ATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHE.AVAAMSKD.A
Retrocopy FTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA

Parental  NMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG--GMGLSNQSSYGG
          NMQHRY.ELFLNST.GAS.GAY..........S......G.......G..G.G...Q.S.GG
Retrocopy NMQHRYIELFLNSTTGASNGAYSSQMMQGMGVSAQSTYSGLESQSVSGCYGAGYGGQNSMGG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	36.50 RPM	186.85 RPM
SRP017611_kidney	162.73 RPM	293.20 RPM
SRP017611_liver	92.09 RPM	215.42 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_131 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_131 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008888	2 retrocopies	retro_amel_57, retro_amel_9,
Bos taurus	ENSBTAG00000009389	1 retrocopy	retro_btau_130,
Choloepus hoffmanni	ENSCHOG00000003841	4 retrocopies	retro_chof_1051, retro_chof_1235, retro_chof_1491, retro_chof_2650,
Callithrix jacchus	ENSCJAG00000009931	1 retrocopy	retro_cjac_127,
Cavia porcellus	ENSCPOG00000001485	5 retrocopies	retro_cpor_1065, retro_cpor_1094, retro_cpor_1095, retro_cpor_121, retro_cpor_711,
Equus caballus	ENSECAG00000014429	1 retrocopy	retro_ecab_94,
Echinops telfairi	ENSETEG00000011303	1 retrocopy	retro_etel_50,
Felis catus	ENSFCAG00000001204	2 retrocopies	retro_fcat_131 , retro_fcat_27,
Homo sapiens	ENSG00000169045	2 retrocopies	retro_hsap_3322, retro_hsap_4911,
Myotis lucifugus	ENSMLUG00000016625	1 retrocopy	retro_mluc_124,
Macaca mulatta	ENSMMUG00000010843	1 retrocopy	retro_mmul_2,
Monodelphis domestica	ENSMODG00000009436	3 retrocopies	retro_mdom_1301, retro_mdom_1302, retro_mdom_333,
Otolemur garnettii	ENSOGAG00000012631	2 retrocopies	retro_ogar_208, retro_ogar_498,
Ochotona princeps	ENSOPRG00000003513	1 retrocopy	retro_opri_11,
Procavia capensis	ENSPCAG00000006715	1 retrocopy	retro_pcap_4,
Pongo abelii	ENSPPYG00000016121	1 retrocopy	retro_pabe_110,
Pteropus vampyrus	ENSPVAG00000007670	1 retrocopy	retro_pvam_23,
Rattus norvegicus	ENSRNOG00000003399	1 retrocopy	retro_rnor_340,
Sorex araneus	ENSSARG00000003024	1 retrocopy	retro_sara_29,
Sarcophilus harrisii	ENSSHAG00000018204	1 retrocopy	retro_shar_674,
Sus scrofa	ENSSSCG00000014022	1 retrocopy	retro_sscr_70,
Vicugna pacos	ENSVPAG00000007485	2 retrocopies	retro_vpac_594, retro_vpac_614,