RetrogeneDB ID: retro_ecab_503

Retrocopy location

• Organism: Horse (Equus caballus)
• Coordinates: 2:98174794..98175215(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SRP19
• Ensembl ID: ENSECAG00000008895
• Aliases: None
• Description: signal recognition particle 19kDa [Source:HGNC Symbol;Acc:11300]

Sequence

>retro_ecab_503
ATGATTTGCACAGCTGTGTGATCCCCAGCTGAGCAGAGCAGCTTCATTTATGTCTATCCTCCATATTTAAATAATAATAA
GACCATAACAGAAGGAGATGGATCCCATAGATAAGGCTGTTGAAAAGTCCTACAGCTACAGAGATCCAAGATAAATGCTC
TGTGGTTGGACTTAATGCATTTCTTGAGAAAAATAAAATATACTCTAGAGAATGCAATTGTGACTTTCAATACAGGGGCA
TAGTTAGGGTCCAGATCAATCAGGATGATGGCATACAGTGTCTCATAAATTTCCTGCTATGTAAATCAGTAATGTATAGA
GCAGAGAGATACATCAACTAAAATAGAATTACACAAAAAATAGAAGATGGGACCAAAGTCTATGGCAAGGAGAGGGAAAT
CACAAAAGGAAGGGGAAAAGA

Alignment

ORF - retro_ecab_503 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 59.03 %
• Parental protein coverage: 98.61 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MACAAARSPAEQDRFFCIYPAYLNNKKTIAEG-RRIPISKAVENPTATEIQDVCSAVGLNVFLERNKMYS
          M.C.A..SPAEQ..F...YP.YLNN.KTI.EG.R.IP.......PTATEIQD.CS.VGLN.FLE.NK.YS
Retrocopy MICTAV*SPAEQSSFIYVYPPYLNNNKTITEG<RWIP*IRLLKSPTATEIQDKCSVVGLNAFLEKNKIYS

Parental  REWNRDAQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYVAEMIPKLKTRTQKTGGG-DQSLQQGEGSKKG
          RE.N.D.QYRG.VRVQ..Q.DG..CL..F...KSVM.Y.AE........TQK...G.DQSL.QGEG..K.
Retrocopy RECNCDFQYRGIVRVQINQDDGIQCLINFLLCKSVM-YRAERYIN*NRITQKIEDG<DQSLWQGEGNHKR

Parental  KGKK
          KGK.
Retrocopy KGKR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP021940_articular_cartilage	0.00 RPM	9.27 RPM
SRP021940_cerebellum	0.00 RPM	9.76 RPM
SRP021940_embryo	0.00 RPM	17.98 RPM
SRP021940_placental_villous	0.00 RPM	11.93 RPM
SRP021940_synovial_membrane	0.00 RPM	16.03 RPM
SRP021940_testis	0.00 RPM	9.85 RPM

ChIP-Seq

Equus caballus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ecab_503 retrocopy.

TSS

Equus caballus was not studied using FANTOM5 data.

Lab

retro_ecab_503 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ecab_503 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 50 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000031549	5 retrocopies	retro_cfam_1207, retro_cfam_1717, retro_cfam_1791, retro_cfam_2174, retro_cfam_848,
Choloepus hoffmanni	ENSCHOG00000013452	2 retrocopies	retro_chof_2525, retro_chof_636,
Callithrix jacchus	ENSCJAG00000016512	4 retrocopies	retro_cjac_1117, retro_cjac_3059, retro_cjac_3144, retro_cjac_886,
Equus caballus	ENSECAG00000008895	1 retrocopy	retro_ecab_503 ,
Erinaceus europaeus	ENSEEUG00000007298	2 retrocopies	retro_eeur_593, retro_eeur_646,
Echinops telfairi	ENSETEG00000017132	4 retrocopies	retro_etel_1016, retro_etel_119, retro_etel_1268, retro_etel_1599,
Felis catus	ENSFCAG00000025895	1 retrocopy	retro_fcat_1732,
Homo sapiens	ENSG00000153037	1 retrocopy	retro_hsap_835,
Macropus eugenii	ENSMEUG00000012529	2 retrocopies	retro_meug_1220, retro_meug_1596,
Microcebus murinus	ENSMICG00000000399	1 retrocopy	retro_mmur_502,
Myotis lucifugus	ENSMLUG00000014793	3 retrocopies	retro_mluc_1097, retro_mluc_350, retro_mluc_710,
Macaca mulatta	ENSMMUG00000000331	2 retrocopies	retro_mmul_1088, retro_mmul_1970,
Monodelphis domestica	ENSMODG00000013278	3 retrocopies	retro_mdom_1366, retro_mdom_1880, retro_mdom_663,
Mustela putorius furo	ENSMPUG00000012695	2 retrocopies	retro_mputfur_602, retro_mputfur_706,
Mus musculus	ENSMUSG00000014504	3 retrocopies	retro_mmus_1680, retro_mmus_3241, retro_mmus_686,
Nomascus leucogenys	ENSNLEG00000011571	1 retrocopy	retro_nleu_3068,
Oryctolagus cuniculus	ENSOCUG00000015639	3 retrocopies	retro_ocun_1003, retro_ocun_1548, retro_ocun_729,
Otolemur garnettii	ENSOGAG00000008579	1 retrocopy	retro_ogar_2070,
Ochotona princeps	ENSOPRG00000010549	3 retrocopies	retro_opri_400, retro_opri_75, retro_opri_793,
Pongo abelii	ENSPPYG00000029584	1 retrocopy	retro_pabe_1569,
Pteropus vampyrus	ENSPVAG00000004895	1 retrocopy	retro_pvam_1465,
Rattus norvegicus	ENSRNOG00000020204	2 retrocopies	retro_rnor_1340, retro_rnor_997,
Ictidomys tridecemlineatus	ENSSTOG00000000348	2 retrocopies	retro_itri_318, retro_itri_831,