RetrogeneDB ID: retro_ecab_1130

Retrocopy location

• Organism: Horse (Equus caballus)
• Coordinates: X:105343875..105344150(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HMGN1
• Ensembl ID: ENSECAG00000019029
• Aliases: None
• Description: high mobility group nucleosome binding domain 1 [Source:HGNC Symbol;Acc:4984]

Sequence

>retro_ecab_1130
AAGGTCAATTCAGTCGAAGGGGTGGTGAAGGGAGAGCCCAAGAGACTTGTGAGGTTGTCAGCTAAATCTACTCCTGCAAA
GGTGGAAACAATGCCCAAAAAGGCAGCAAGAAAGGATAAACTCTCAGATCAAAAAGTGCGAACAAAAGGGAAAAGGAGAA
GAAGGGGCAAACAGGCAGAAATGGTTAACTAAGAAACTAAAGATTGGCATGCAGAAAACAGAGAACTGAAAATGAGCAGA
ATCCAGCCTCTAATGAAGCAGGAGTGAAAGAAGCT

Alignment

ORF - retro_ecab_1130 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 64.21 %
• Parental protein coverage: 94. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  QVSSAEGAAKEEPKRRSARLSAKPAPAKVETKPKKVAGKDKSSDKKVQTKGKRGAKGKQAEVANQETKED
          .V.S.EG..K.EPKR...RLSAK..PAKVET.PKK.A.KDK.SD.KV.TKGKR...GKQAE..N.ETK.D
Retrocopy KVNSVEGVVKGEPKRL-VRLSAKSTPAKVETMPKKAARKDKLSDQKVRTKGKRRRRGKQAEMVN*ETK-D

Parental  LPAENGE-TKNEESAASDEAGEKEA
          ..AEN.E.T.NE...AS.EAG.KEA
Retrocopy WHAENRE<TENEQNPASNEAGVKEA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP021940_articular_cartilage	0.00 RPM	11.81 RPM
SRP021940_cerebellum	0.00 RPM	13.29 RPM
SRP021940_embryo	0.00 RPM	92.42 RPM
SRP021940_placental_villous	0.00 RPM	22.66 RPM
SRP021940_synovial_membrane	0.00 RPM	18.72 RPM
SRP021940_testis	0.00 RPM	24.04 RPM

ChIP-Seq

Equus caballus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ecab_1130 retrocopy.

TSS

Equus caballus was not studied using FANTOM5 data.

Lab

retro_ecab_1130 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ecab_1130 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Bos taurus	retro_btau_1801
Canis familiaris	retro_cfam_2202

---

Parental genes homology:

Parental genes homology involve 9 parental genes, and 129 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000014100	11 retrocopies	retro_amel_1103, retro_amel_1157, retro_amel_1307, retro_amel_1378, retro_amel_1580, retro_amel_1839, retro_amel_349, retro_amel_352, retro_amel_408, retro_amel_439, retro_amel_670,
Bos taurus	ENSBTAG00000018768	12 retrocopies	retro_btau_1178, retro_btau_1475, retro_btau_1560, retro_btau_1746, retro_btau_1801, retro_btau_388, retro_btau_504, retro_btau_572, retro_btau_607, retro_btau_617, retro_btau_897, retro_btau_928,
Cavia porcellus	ENSCPOG00000002336	7 retrocopies	retro_cpor_1129, retro_cpor_1389, retro_cpor_334, retro_cpor_349, retro_cpor_4, retro_cpor_884, retro_cpor_949,
Equus caballus	ENSECAG00000019029	5 retrocopies	retro_ecab_1130 , retro_ecab_285, retro_ecab_362, retro_ecab_800, retro_ecab_848,
Homo sapiens	ENSG00000205581	7 retrocopies	retro_hsap_1097, retro_hsap_1418, retro_hsap_1581, retro_hsap_1758, retro_hsap_1874, retro_hsap_3370, retro_hsap_762,
Monodelphis domestica	ENSMODG00000020972	5 retrocopies	retro_mdom_1085, retro_mdom_109, retro_mdom_284, retro_mdom_755, retro_mdom_88,
Otolemur garnettii	ENSOGAG00000010329	35 retrocopies	retro_ogar_1062, retro_ogar_1186, retro_ogar_1245, retro_ogar_1304, retro_ogar_1355, retro_ogar_1437, retro_ogar_1527, retro_ogar_1529, retro_ogar_175, retro_ogar_1812, retro_ogar_1901, retro_ogar_1932, retro_ogar_2057, retro_ogar_2311, retro_ogar_2325, retro_ogar_2522, retro_ogar_2523, retro_ogar_266, retro_ogar_2712, retro_ogar_2729, retro_ogar_278, retro_ogar_2913, retro_ogar_2964, retro_ogar_3095, retro_ogar_3133, retro_ogar_3138, retro_ogar_3155, retro_ogar_333, retro_ogar_3354, retro_ogar_370, retro_ogar_393, retro_ogar_657, retro_ogar_699, retro_ogar_723, retro_ogar_958,
Pongo abelii	ENSPPYG00000011426	25 retrocopies	retro_pabe_1066, retro_pabe_1149, retro_pabe_1172, retro_pabe_1190, retro_pabe_123, retro_pabe_1264, retro_pabe_1302, retro_pabe_1504, retro_pabe_1604, retro_pabe_1842, retro_pabe_2152, retro_pabe_2211, retro_pabe_2284, retro_pabe_2380, retro_pabe_251, retro_pabe_2518, retro_pabe_2771, retro_pabe_3086, retro_pabe_3648, retro_pabe_3825, retro_pabe_504, retro_pabe_698, retro_pabe_699, retro_pabe_702, retro_pabe_760,
Pan troglodytes	ENSPTRG00000031426	22 retrocopies	retro_ptro_1256, retro_ptro_1299, retro_ptro_1301, retro_ptro_1454, retro_ptro_1556, retro_ptro_1740, retro_ptro_1821, retro_ptro_1830, retro_ptro_2058, retro_ptro_2290, retro_ptro_2559, retro_ptro_2716, retro_ptro_3119, retro_ptro_3278, retro_ptro_363, retro_ptro_463, retro_ptro_586, retro_ptro_61, retro_ptro_637, retro_ptro_696, retro_ptro_970, retro_ptro_980,