RetrogeneDB ID: retro_cjac_822

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 11:9054562..9055536(+)
• Located in intron of: ENSCJAG00000010496

Retrocopy information

• Ensembl ID: ENSCJAG00000010527
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCJAG00000009147
• Aliases: None
• Description: None

Sequence

>retro_cjac_822
ATGGCGGATTTAGACAAACTCAACATCGACAGCATCATCCAACGGCTGCCGGAAGTGAGAGGGTCCAAGCCTGGTAAGAA
TGTCCAGCTTCAGGAGAATGAAATCAGAGGACTGTGCCTAAAGTCTCCTGAGATCTTTCTCAGTCAGCCCATCCTACTAG
AACTTGAAGCACCACTCAAAATATGTGGTGACATCCATGGGCAATACTACGATTTGCTGCGACTTTTCGAGTACGGTGGT
TTCCCGCCAGAAAGCAACTACCTGTTTCTTGGGGACTCTGTGGACAGGGGAAAGCAGTCATTGGAGACAATCTGCCTCTT
CCTGGCCTACAAAATCAAATATCCTGAGAATTGTTTTCTTCTCAGAGGGAACCATGAATGTGCCAGCATCAACAGAATTT
ATGGATTTTATGATGAATGTAAAAGAAGATACAACATTAAACTATGGAAAACTTTCACAGACCGTTTTAACTGTTTACCG
ATAGCAGCCATCGTGGATGAGAAGATATTCTGCTGTGATGGAGAATTATCTTTATCGCCAGATCTTCAATCTATGGAGCA
GATTCGGAGAATTATGCGACCAACTGATGTACCAGGTCAAGGTCTTCTCTGTGATCCTTTGTGGTCTGACCCCAATAAAG
ATCTTAGGCTGGGGTGAAAATGACAGAGGAGTGCCCTTCACATTTGGTGAAGAAGTGGTTGCAAAAATTTCTCCATAAGC
ACGATTTGGATCTTATATGTAGAGTCCATCAGGTGGTTGAAGATGGATATGAATTTTTTGCAAAGAGGCAGTTGGTCACT
CTGTTTTCTGCACACAATGATTGTGGAGAGTTTGACAATGCAGGTGCCATGATGAGTGTGGACAAAACACTAATGTGTTC
TTTTCAGATTTTAAAGCCTGCAGAGAAGAAGAAGCCAAATGCCACGAAACCTGTAACACCTCCAAGGGGTATGATCACAA
AACAAGCAAAGAAA

Alignment

ORF - retro_cjac_822 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.66 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYY
          MADLDKLNIDSIIQRL.EVRGSKPGKNVQLQENEIRGLCLKS.EIFLSQPILLELEAPLKICGDIHGQYY
Retrocopy MADLDKLNIDSIIQRLPEVRGSKPGKNVQLQENEIRGLCLKSPEIFLSQPILLELEAPLKICGDIHGQYY

Parental  DLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDEC
          DLLRLFEYGGFPPESNYLFLGD.VDRGKQSLETICL.LAYKIKYPEN.FLLRGNHECASINRIYGFYDEC
Retrocopy DLLRLFEYGGFPPESNYLFLGDSVDRGKQSLETICLFLAYKIKYPENCFLLRGNHECASINRIYGFYDEC

Parental  KRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHG--GLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD
          KRRYNIKLWKTFTD.FNCLPIAAIVDEKIFCC.G...LSPDLQSMEQIRRIMRPTDVP.QGLLCD.LWSD
Retrocopy KRRYNIKLWKTFTDRFNCLPIAAIVDEKIFCCDGELSLSPDLQSMEQIRRIMRPTDVPGQGLLCDPLWSD

Parental  -PDKDVLGWGENDRGVSFTFGAEVVAK-FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEF
          .P.K..LGWGENDRGV.FTFG.EVVAK.FLHKHDLDLICR.HQVVEDGYEFFAKRQLVTLFSA.N.CGEF
Retrocopy >PIK-ILGWGENDRGVPFTFGEEVVAK>FLHKHDLDLICRVHQVVEDGYEFFAKRQLVTLFSAHNDCGEF

Parental  DNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
          DNAGAMMSVD.TLMCSFQILKPAEKKKPNAT.PVTPPRGMITKQAKK
Retrocopy DNAGAMMSVDKTLMCSFQILKPAEKKKPNATKPVTPPRGMITKQAKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.40 RPM	63.72 RPM
SRP051959_heart	0.74 RPM	62.29 RPM
SRP051959_kidney	0.27 RPM	51.38 RPM
SRP051959_liver	0.26 RPM	41.91 RPM
SRP051959_lung	0.75 RPM	67.66 RPM
SRP051959_lymph_node	0.59 RPM	105.75 RPM
SRP051959_skeletal_muscle	0.22 RPM	62.13 RPM
SRP051959_spleen	0.65 RPM	93.21 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_822 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_822 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_822 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000013861	1 retrocopy	retro_amel_1721,
Bos taurus	ENSBTAG00000011198	2 retrocopies	retro_btau_6, retro_btau_960,
Ciona intestinalis	ENSCING00000004542	1 retrocopy	retro_cint_3,
Callithrix jacchus	ENSCJAG00000000983	1 retrocopy	retro_cjac_923,
Callithrix jacchus	ENSCJAG00000009147	7 retrocopies	retro_cjac_1062, retro_cjac_1165, retro_cjac_1408, retro_cjac_2304, retro_cjac_2535, retro_cjac_3288, retro_cjac_822 ,
Dipodomys ordii	ENSDORG00000010484	2 retrocopies	retro_dord_260, retro_dord_261,
Equus caballus	ENSECAG00000017228	1 retrocopy	retro_ecab_853,
Echinops telfairi	ENSETEG00000015721	1 retrocopy	retro_etel_2065,
Myotis lucifugus	ENSMLUG00000010661	2 retrocopies	retro_mluc_15, retro_mluc_2217,
Mus musculus	ENSMUSG00000004455	5 retrocopies	retro_mmus_2274, retro_mmus_2968, retro_mmus_3418, retro_mmus_851, retro_mmus_925,
Oryctolagus cuniculus	ENSOCUG00000009275	2 retrocopies	retro_ocun_1232, retro_ocun_665,
Pan troglodytes	ENSPTRG00000005448	1 retrocopy	retro_ptro_2435,
Sorex araneus	ENSSARG00000000571	1 retrocopy	retro_sara_700,
Tupaia belangeri	ENSTBEG00000013852	4 retrocopies	retro_tbel_1710, retro_tbel_2116, retro_tbel_2311, retro_tbel_4450,
Vicugna pacos	ENSVPAG00000008411	1 retrocopy	retro_vpac_540,
Drosophila melanogaster	FBgn0003134	5 retrocopies	retro_dmel_21, retro_dmel_37, retro_dmel_42, retro_dmel_48, retro_dmel_81,