RetrogeneDB ID: retro_cjac_2991

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 7:77575584..77576187(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MKRN1
• Ensembl ID: ENSCJAG00000013474
• Aliases: None
• Description: makorin ring finger protein 1 [Source:HGNC Symbol;Acc:7112]

Sequence

>retro_cjac_2991
AGATATGAACATAGCAAGCCATTGAAATAGGAAGAAGCAACTGCTACAGAGCTAACTACAAAGTCATCCCTTGCTGCTTC
CTCAAGTCTCTCATTGATAGTTGGATCACTTGTTGAAATGAATACAGGAAAGCTGAGTCAAGAAATTCAAACTTTGCAAC
TGTAGGAGCAGGTTCAGAGGACTGGGTGAATGCTATTGAGTTTGTTCTTGGGCAACCCTATTGTGGCTGTACTGGGCCTT
CCTGCACTGAAGCACGTCTGCTGGGCTCAGTGACCAAGGAAGAATCAGAAGGAAAAAACCGCCACGGAAACAAAGAAGCA
GCTGTGCCCCTATGCTGCAATGGGAGAGTGCCTATATTAGGAGAACTGTGTGCTATCTCCATGGAGATTCATGTGACATG
TGTGGGCTGCAGGTCCTGCATCCGATGGATGCTACCCAGAGATCACAGCATGTAAAATTGTGCATTGAGAAGGACATGGC
ACTCTCATTTGCTCTGCAGCGCAGCAAGGACATGGTGTGTAGGATCTGCATGGAGGTAGGTGGTCTCCCAGGAAAGCCAA
CCCCAGCGAGCACTGCTTCAGGATCCTCTCCAACTACAGTCAC

Alignment

ORF - retro_cjac_2991 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.16 %
• Parental protein coverage: 53.7 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  RYEHSKPVKQEEAAATELTTKSSLATSSSLSSVVGPLVEMNTSD-AESRNSNFATVGAGSEDWVNAIEFV
          RYEHSKP.K.EEA.ATELTTKSSLA.SSSLS..VG.LVEMNT...AESRNSNFATVGAGSEDWVNAIEFV
Retrocopy RYEHSKPLK*EEATATELTTKSSLAASSSLSLIVGSLVEMNTGK<AESRNSNFATVGAGSEDWVNAIEFV

Parental  PGQPYCGRTAPSCTEAPLQGSVTKEESE-KEQTTVETKKQLCPYAAVGECRYGENCV-YLHGDSCDMCGL
          .GQPYCG.T.PSCTEA.L.GSVTKEESE.....T...K..LCPYAA.GEC.Y.ENCV.YLHGDSCDMCGL
Retrocopy LGQPYCGCTGPSCTEARLLGSVTKEESE>EKTATETKKQ-LCPYAAMGECLY*ENCV>YLHGDSCDMCGL

Parental  QVLHPMDAAQRSEHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEV--VYEKANPSERRFG-ILSNCNH
          QVLHPMDA.QRS.H.K.CIE...KDM.LSFA.QRSKDMVC.ICMEV.....K..P.....G.ILSN..H
Retrocopy QVLHPMDATQRSQHVKLCIE---KDMALSFALQRSKDMVCRICMEVGGLPGKPTPASTASG<ILSNYSH

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.47 RPM	35.41 RPM
SRP051959_heart	0.40 RPM	25.40 RPM
SRP051959_kidney	0.64 RPM	45.59 RPM
SRP051959_liver	0.26 RPM	25.00 RPM
SRP051959_lung	0.54 RPM	42.44 RPM
SRP051959_lymph_node	0.37 RPM	27.26 RPM
SRP051959_skeletal_muscle	0.52 RPM	31.14 RPM
SRP051959_spleen	0.46 RPM	35.92 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_2991 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_2991 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_2991 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 54 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000008306	2 retrocopies	retro_btau_401, retro_btau_943,
Canis familiaris	ENSCAFG00000003953	2 retrocopies	retro_cfam_2157, retro_cfam_253,
Choloepus hoffmanni	ENSCHOG00000011015	3 retrocopies	retro_chof_173, retro_chof_2357, retro_chof_89,
Callithrix jacchus	ENSCJAG00000013474	2 retrocopies	retro_cjac_210, retro_cjac_2991 ,
Callithrix jacchus	ENSCJAG00000016733	1 retrocopy	retro_cjac_2362,
Cavia porcellus	ENSCPOG00000000948	1 retrocopy	retro_cpor_109,
Dasypus novemcinctus	ENSDNOG00000019564	2 retrocopies	retro_dnov_1011, retro_dnov_388,
Erinaceus europaeus	ENSEEUG00000001133	1 retrocopy	retro_eeur_643,
Felis catus	ENSFCAG00000024942	1 retrocopy	retro_fcat_67,
Homo sapiens	ENSG00000133606	4 retrocopies	retro_hsap_1140, retro_hsap_4197, retro_hsap_4676, retro_hsap_4859,
Gorilla gorilla	ENSGGOG00000023977	4 retrocopies	retro_ggor_119, retro_ggor_2813, retro_ggor_3031, retro_ggor_381,
Macropus eugenii	ENSMEUG00000007399	1 retrocopy	retro_meug_1659,
Microcebus murinus	ENSMICG00000002114	1 retrocopy	retro_mmur_1184,
Macaca mulatta	ENSMMUG00000010420	3 retrocopies	retro_mmul_191, retro_mmul_2597, retro_mmul_76,
Mus musculus	ENSMUSG00000029922	1 retrocopy	retro_mmus_2663,
Nomascus leucogenys	ENSNLEG00000001921	4 retrocopies	retro_nleu_1027, retro_nleu_2167, retro_nleu_33, retro_nleu_939,
Otolemur garnettii	ENSOGAG00000009877	2 retrocopies	retro_ogar_3468, retro_ogar_424,
Ochotona princeps	ENSOPRG00000010353	1 retrocopy	retro_opri_1073,
Procavia capensis	ENSPCAG00000014683	1 retrocopy	retro_pcap_19,
Pongo abelii	ENSPPYG00000018057	3 retrocopies	retro_pabe_3435, retro_pabe_3776, retro_pabe_947,
Pan troglodytes	ENSPTRG00000019766	5 retrocopies	retro_ptro_2849, retro_ptro_3106, retro_ptro_3234, retro_ptro_75, retro_ptro_776,
Sus scrofa	ENSSSCG00000016498	2 retrocopies	retro_sscr_43, retro_sscr_637,
Tupaia belangeri	ENSTBEG00000004564	2 retrocopies	retro_tbel_1410, retro_tbel_71,
Tarsius syrichta	ENSTSYG00000009996	3 retrocopies	retro_tsyr_1256, retro_tsyr_1525, retro_tsyr_508,
Tursiops truncatus	ENSTTRG00000009528	2 retrocopies	retro_ttru_1064, retro_ttru_1128,